pLV-dCas9-KRAB-PGK-HygR Citations (6)

Originally described in: CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.
Klann TS, Black JB, Chellappan M, Safi A, Song L, Hilton IB, Crawford GE, Reddy TE, Gersbach CA Nat Biotechnol. 2017 Apr 3. doi: 10.1038/nbt.3853. PubMed Journal

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Articles Citing pLV-dCas9-KRAB-PGK-HygR

Articles
Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing. Klann TS, Crawford GE, Reddy TE, Gersbach CA. Methods Mol Biol. 2018;1767:447-480. doi: 10.1007/978-1-4939-7774-1_25. PubMed
HoxA9 transforms murine myeloid cells by a feedback loop driving expression of key oncogenes and cell cycle control genes. Zhong X, Prinz A, Steger J, Garcia-Cuellar MP, Radsak M, Bentaher A, Slany RK. Blood Adv. 2018 Nov 27;2(22):3137-3148. doi: 10.1182/bloodadvances.2018025866. PubMed
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML. Duy C, Teater M, Garrett-Bakelman FE, Lee TC, Meydan C, Glass JL, Li M, Hellmuth JC, Mohammad HP, Smitheman KN, Shih AH, Abdel-Wahab O, Tallman MS, Guzman ML, Muench D, Grimes HL, Roboz GJ, Kruger RG, Creasy CL, Paietta EM, Levine RL, Carroll M, Melnick AM. Cancer Discov. 2019 Jul;9(7):872-889. doi: 10.1158/2159-8290.CD-19-0106. Epub 2019 May 10. PubMed
Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation and is altered with age. Maybury-Lewis SY, Brown AK, Yeary M, Sloutskin A, Dhakal S, Juven-Gershon T, Webb AE. Aging Cell. 2021 Nov;20(11):e13499. doi: 10.1111/acel.13499. Epub 2021 Oct 23. PubMed
Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure. Bohnsack JP, Zhang H, Wandling GM, He D, Kyzar EJ, Lasek AW, Pandey SC. Sci Adv. 2022 May 6;8(18):eabn2748. doi: 10.1126/sciadv.abn2748. Epub 2022 May 4. PubMed
Integrated enhancer regulatory network by enhancer-promoter looping in gastric cancer. Zhu T, Okabe A, Usui G, Fujiki R, Komiyama D, Huang KK, Seki M, Fukuyo M, Abe H, Ning M, Okada T, Minami M, Matsumoto M, Fan Q, Rahmutulla B, Hoshii T, Tan P, Morikawa T, Ushiku T, Kaneda A. NAR Cancer. 2024 May 8;6(2):zcae020. doi: 10.1093/narcan/zcae020. eCollection 2024 Jun. PubMed

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