pCW-Cas9-Blast Citations (21)
Originally described in: CRISPR/Cas9-based system for loss-of-function screeningHabashy et al Unpublished
Articles Citing pCW-Cas9-Blast
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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling. Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohee L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G, de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K. Cell. 2021 Feb 4;184(3):655-674.e27. doi: 10.1016/j.cell.2020.12.024. Epub 2021 Jan 25. PubMed |
Myogenin suppresses apoptosis induced by angiotensin II in human induced pluripotent stem cell-derived cardiomyocytes. Gao Q, Wang P, Qiu H, Qiu B, Yi W, Tu W, Lin B, Sun D, Zeng R, Huang M, Chen J, Cen J, Zhuang J. Biochem Biophys Res Commun. 2021 May 7;552:84-90. doi: 10.1016/j.bbrc.2021.03.031. Epub 2021 Mar 17. PubMed |
Neuronal enhancers are hotspots for DNA single-strand break repair. Wu W, Hill SE, Nathan WJ, Paiano J, Callen E, Wang D, Shinoda K, van Wietmarschen N, Colon-Mercado JM, Zong D, De Pace R, Shih HY, Coon S, Parsadanian M, Pavani R, Hanzlikova H, Park S, Jung SK, McHugh PJ, Canela A, Chen C, Casellas R, Caldecott KW, Ward ME, Nussenzweig A. Nature. 2021 May;593(7859):440-444. doi: 10.1038/s41586-021-03468-5. Epub 2021 Mar 25. PubMed |
B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition. Chen Y, Fachko DN, Ivanov NS, Skalsky RL. mSphere. 2021 Apr 14;6(2). pii: 6/2/e00093-21. doi: 10.1128/mSphere.00093-21. PubMed |
Viral tegument proteins restrict cGAS-DNA phase separation to mediate immune evasion. Xu G, Liu C, Zhou S, Li Q, Feng Y, Sun P, Feng H, Gao Y, Zhu J, Luo X, Zhan Q, Liu S, Zhu S, Deng H, Li D, Gao P. Mol Cell. 2021 Jul 1;81(13):2823-2837.e9. doi: 10.1016/j.molcel.2021.05.002. Epub 2021 May 19. PubMed |
LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components. Fan Y, Koberlin MS, Ratnayeke N, Liu C, Deshpande M, Gerhardt J, Meyer T. J Cell Biol. 2021 Aug 2;220(8). pii: 212186. doi: 10.1083/jcb.202009147. Epub 2021 May 26. PubMed |
Molecular control of cell density-mediated exit to quiescence. Fan Y, Meyer T. Cell Rep. 2021 Jul 27;36(4):109436. doi: 10.1016/j.celrep.2021.109436. PubMed |
piggyPrime: High-Efficacy Prime Editing in Human Cells Using piggyBac-Based DNA Transposition.
Wolff JH, Haldrup J, Thomsen EA, Andersen S, Mikkelsen JG.
Front Genome Ed. 2021 Nov 12;3:786893. doi: 10.3389/fgeed.2021.786893. eCollection 2021.
PubMed
Associated Plasmids |
Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factor.
Danziger O, Patel RS, DeGrace EJ, Rosen MR, Rosenberg BR.
PLoS Pathog. 2022 Apr 14;18(4):e1010464. doi: 10.1371/journal.ppat.1010464. eCollection 2022 Apr.
PubMed
Associated Plasmids |
SETD2 Haploinsufficiency Enhances Germinal Center-Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis. Leung W, Teater M, Durmaz C, Meydan C, Chivu AG, Chadburn A, Rice EJ, Muley A, Camarillo JM, Arivalagan J, Li Z, Flowers CR, Kelleher NL, Danko CG, Imielinski M, Dave SS, Armstrong SA, Mason CE, Melnick AM. Cancer Discov. 2022 Jul 6;12(7):1782-1803. doi: 10.1158/2159-8290.CD-21-1514. PubMed |
A non-canonical vitamin K cycle is a potent ferroptosis suppressor. Mishima E, Ito J, Wu Z, Nakamura T, Wahida A, Doll S, Tonnus W, Nepachalovich P, Eggenhofer E, Aldrovandi M, Henkelmann B, Yamada KI, Wanninger J, Zilka O, Sato E, Feederle R, Hass D, Maida A, Mourao ASD, Linkermann A, Geissler EK, Nakagawa K, Abe T, Fedorova M, Proneth B, Pratt DA, Conrad M. Nature. 2022 Aug;608(7924):778-783. doi: 10.1038/s41586-022-05022-3. Epub 2022 Aug 3. PubMed |
Programmable eukaryotic protein synthesis with RNA sensors by harnessing ADAR.
Jiang K, Koob J, Chen XD, Krajeski RN, Zhang Y, Volf V, Zhou W, Sgrizzi SR, Villiger L, Gootenberg JS, Chen F, Abudayyeh OO.
Nat Biotechnol. 2022 Oct 27. pii: 10.1038/s41587-022-01534-5. doi: 10.1038/s41587-022-01534-5.
PubMed
Associated Plasmids |
ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis. Wang R, Bhatt AB, Minden-Birkenmaier BA, Travis OK, Tiwari S, Jia H, Rosikiewicz W, Martinot O, Childs E, Loesch R, Tossou G, Jamieson S, Finkelstein D, Xu B, Labelle M. Sci Adv. 2023 Jan 6;9(1):eabq3951. doi: 10.1126/sciadv.abq3951. Epub 2023 Jan 6. PubMed |
Systematic elucidation of genetic mechanisms underlying cholesterol uptake.
Hamilton MC, Fife JD, Akinci E, Yu T, Khowpinitchai B, Cha M, Barkal S, Thi TT, Yeo GHT, Barroso JPR, Francoeur MJ, Velimirovic M, Gifford DK, Lettre G, Yu H, Cassa CA, Sherwood RI.
bioRxiv. 2023 Jan 10:2023.01.09.500804. doi: 10.1101/2023.01.09.500804. Preprint.
PubMed
Associated Plasmids |
Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B. Muys BR, Shrestha RL, Anastasakis DG, Pongor L, Li XL, Grammatikakis I, Polash A, Chari R, Gorospe M, Harris CC, Aladjem MI, Basrai MA, Hafner M, Lal A. Cell Rep. 2023 Mar 28;42(3):112260. doi: 10.1016/j.celrep.2023.112260. Epub 2023 Mar 15. PubMed |
Phase separation of FSP1 promotes ferroptosis. Nakamura T, Hipp C, Santos Dias Mourao A, Borggrafe J, Aldrovandi M, Henkelmann B, Wanninger J, Mishima E, Lytton E, Emler D, Proneth B, Sattler M, Conrad M. Nature. 2023 Jul;619(7969):371-377. doi: 10.1038/s41586-023-06255-6. Epub 2023 Jun 28. PubMed |
DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition. Mishima E, Nakamura T, Zheng J, Zhang W, Mourao ASD, Sennhenn P, Conrad M. Nature. 2023 Jul;619(7968):E9-E18. doi: 10.1038/s41586-023-06269-0. Epub 2023 Jul 5. PubMed |
GiRAFR improves gRNA detection and annotation in single-cell CRISPR screens. Yu Q, Van Minsel P, Galle E, Thienpont B. Commun Biol. 2023 Sep 23;6(1):975. doi: 10.1038/s42003-023-05351-7. PubMed |
Patient-derived response estimates from zero-passage organoids of luminal breast cancer. Przanowska RK, Labban N, Przanowski P, Hawes RB, Atkins KA, Showalter SL, Janes KA. bioRxiv [Preprint]. 2024 Mar 27:2024.03.24.586432. doi: 10.1101/2024.03.24.586432. PubMed |
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains. Balachandra V, Shrestha RL, Hammond CM, Lin S, Hendriks IA, Sethi SC, Chen L, Sevilla S, Caplen NJ, Chari R, Karpova TS, McKinnon K, Todd MA, Koparde V, Cheng KC, Nielsen ML, Groth A, Basrai MA. EMBO J. 2024 Jun;43(11):2166-2197. doi: 10.1038/s44318-024-00093-6. Epub 2024 Apr 10. PubMed |
SETDB1 modulates the TGFbeta response in Duchenne muscular dystrophy myotubes. Granados A, Zamperoni M, Rapone R, Moulin M, Boyarchuk E, Bouyioukos C, Del Maestro L, Joliot V, Negroni E, Mohamed M, Piquet S, Bigot A, Le Grand F, Albini S, Ait-Si-Ali S. Sci Adv. 2024 May 3;10(18):eadj8042. doi: 10.1126/sciadv.adj8042. Epub 2024 May 1. PubMed |
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