pGEX-4T1 SHP2 WT Citations (3)

Originally described in: Activated mutants of SHP-2 preferentially induce elongation of Xenopus animal caps.
O'Reilly AM, Pluskey S, Shoelson SE, Neel BG Mol Cell Biol 2000 Jan;20(1):299-311. PubMed Journal

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Articles Citing pGEX-4T1 SHP2 WT

Articles
Molecular mechanism of interleukin-2-induced mucosal homeostasis. Mishra J, Waters CM, Kumar N. Am J Physiol Cell Physiol. 2012 Mar 1;302(5):C735-47. doi: 10.1152/ajpcell.00316.2011. Epub 2011 Nov 23. PubMed
Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis. Guo W, Liu W, Chen Z, Gu Y, Peng S, Shen L, Shen Y, Wang X, Feng GS, Sun Y, Xu Q. Nat Commun. 2017 Dec 18;8(1):2168. doi: 10.1038/s41467-017-02351-0. PubMed
The pathogenic T42A mutation in SHP2 rewires interaction specificity and enhances signaling. van Vlimmeren AE, Voleti R, Chartier CA, Jiang Z, Karandur D, Shah NH. bioRxiv. 2023 Jul 30:2023.07.10.548257. doi: 10.1101/2023.07.10.548257. Preprint. PubMed

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