pCDNA3.1-FLAG-hSF3B1-K700E Citations (6)

Originally described in: Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3' splice sites within RNA secondary structures.
Kesarwani AK, Ramirez O, Gupta AK, Yang X, Murthy T, Minella AC, Pillai MM Oncogene. 2016 Aug 15. doi: 10.1038/onc.2016.279. PubMed Journal

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Articles Citing pCDNA3.1-FLAG-hSF3B1-K700E

Articles
Degenerate minigene library analysis enables identification of altered branch point utilization by mutant splicing factor 3B1 (SF3B1). Gupta AK, Murthy T, Paul KV, Ramirez O, Fisher JB, Rao S, Rosenberg AB, Seelig G, Minella AC, Pillai MM. Nucleic Acids Res. 2018 Nov 20. pii: 5193340. doi: 10.1093/nar/gky1161. PubMed Associated Plasmids sgSf3b1(T1) pL452-Sf3b1-K700E pL452(hygro)-Sf3b1-K700K
SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer. Simmler P, Cortijo C, Koch LM, Galliker P, Angori S, Bolck HA, Mueller C, Vukolic A, Mirtschink P, Christinat Y, Davidson NR, Lehmann KV, Pellegrini G, Pauli C, Lenggenhager D, Guccini I, Ringel T, Hirt C, Marquart KF, Schaefer M, Ratsch G, Peter M, Moch H, Stoffel M, Schwank G. Cell Rep. 2022 Aug 23;40(8):111266. doi: 10.1016/j.celrep.2022.111266. PubMed
Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in myelodysplastic syndrome. Ochi T, Fujiwara T, Ono K, Suzuki C, Nikaido M, Inoue D, Kato H, Onodera K, Ichikawa S, Fukuhara N, Onishi Y, Yokoyama H, Nakamura Y, Harigae H. Sci Rep. 2022 Aug 26;12(1):14562. doi: 10.1038/s41598-022-18921-2. PubMed
The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts. Choi IY, Ling J, Zhang J, Helmenstine E, Walter W, Bergman R, Philippe C, Manley J, Rouault-Pierre K, Li B, Wiseman D, Ouseph M, Bernard E, Li X, Haferlach T, Fazal S, Jain T, Gocke C, DeZern A, Dalton WB. Res Sq. 2023 Apr 14:rs.3.rs-2802265. doi: 10.21203/rs.3.rs-2802265/v1. Preprint. PubMed
Mutant SF3B1 promotes malignancy in PDAC. Simmler P, Ioannidi EI, Mengis T, Marquart KF, Asawa S, Van-Lehmann K, Kahles A, Thomas T, Schwerdel C, Aceto N, Ratsch G, Stoffel M, Schwank G. Elife. 2023 Oct 12;12:e80683. doi: 10.7554/eLife.80683. PubMed
Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape. Boddu PC, Gupta AK, Roy R, De La Pena Avalos B, Olazabal-Herrero A, Neuenkirchen N, Zimmer JT, Chandhok NS, King D, Nannya Y, Ogawa S, Lin H, Simon MD, Dray E, Kupfer GM, Verma A, Neugebauer KM, Pillai MM. Mol Cell. 2024 Apr 18;84(8):1475-1495.e18. doi: 10.1016/j.molcel.2024.02.032. Epub 2024 Mar 22. PubMed

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