pCAG-dCas9-5xPlat2AflD Citations (13)
Originally described in: Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions.Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I Nat Biotechnol. 2016 Aug 29. doi: 10.1038/nbt.3658. PubMed Journal
Articles Citing pCAG-dCas9-5xPlat2AflD
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| Editing of DNA Methylation Using dCas9-Peptide Repeat and scFv-TET1 Catalytic Domain Fusions. Morita S, Horii T, Hatada I. Methods Mol Biol. 2018;1767:419-428. doi: 10.1007/978-1-4939-7774-1_23. PubMed |
| CRISPR-Based Targeted Epigenetic Editing Enables Gene Expression Modulation of the Silenced Beta-Galactoside Alpha-2,6-Sialyltransferase 1 in CHO Cells. Marx N, Grunwald-Gruber C, Bydlinski N, Dhiman H, Ngoc Nguyen L, Klanert G, Borth N. Biotechnol J. 2018 Oct;13(10):e1700217. doi: 10.1002/biot.201700217. Epub 2018 Jun 11. PubMed |
| MICMIC: identification of DNA methylation of distal regulatory regions with causal effects on tumorigenesis. Tong Y, Sun J, Wong CF, Kang Q, Ru B, Wong CN, Chan AS, Leung SY, Zhang J. Genome Biol. 2018 Jun 5;19(1):73. doi: 10.1186/s13059-018-1442-0. PubMed |
| Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding. Le Berre G, Hossard V, Riou JF, Guieysse-Peugeot AL. Int J Mol Sci. 2019 Jun 7;20(11). pii: ijms20112791. doi: 10.3390/ijms20112791. PubMed |
| Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways. Taghbalout A, Du M, Jillette N, Rosikiewicz W, Rath A, Heinen CD, Li S, Cheng AW. Nat Commun. 2019 Sep 20;10(1):4296. doi: 10.1038/s41467-019-12339-7. PubMed |
| Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome. Horii T, Morita S, Hino S, Kimura M, Hino Y, Kogo H, Nakao M, Hatada I. Genome Biol. 2020 Apr 1;21(1):77. doi: 10.1186/s13059-020-01991-8. PubMed |
| TALE.Sense: A Versatile DNA Sensor Platform for Live Mammalian Cells. Taghbalout A, Jillette N, Cheng AW. ACS Synth Biol. 2022 Jan 21;11(1):116-124. doi: 10.1021/acssynbio.1c00212. Epub 2021 Dec 21. PubMed |
| Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain. Kojima S, Shiochi N, Sato K, Yamaura M, Ito T, Yamamura N, Goto N, Odamoto M, Kobayashi S, Kimura T, Sekita Y. Nucleic Acids Res. 2022 May 20;50(9):5080-5094. doi: 10.1093/nar/gkac344. PubMed |
| The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells. Kobayashi N, Okae H, Hiura H, Kubota N, Kobayashi EH, Shibata S, Oike A, Hori T, Kikutake C, Hamada H, Kaji H, Suyama M, Bortolin-Cavaille ML, Cavaille J, Arima T. Nat Commun. 2022 Jun 2;13(1):3071. doi: 10.1038/s41467-022-30775-w. PubMed |
| Genome-wide DNA hypermethylation opposes healing in patients with chronic wounds by impairing epithelial-mesenchymal transition. Singh K, Rustagi Y, Abouhashem AS, Tabasum S, Verma P, Hernandez E, Pal D, Khona DK, Mohanty SK, Kumar M, Srivastava R, Guda PR, Verma SS, Mahajan S, Killian JA, Walker LA, Ghatak S, Mathew-Steiner SS, Wanczyk KE, Liu S, Wan J, Yan P, Bundschuh R, Khanna S, Gordillo GM, Murphy MP, Roy S, Sen CK. J Clin Invest. 2022 Sep 1;132(17):e157279. doi: 10.1172/JCI157279. PubMed |
Activation of stably silenced genes by recruitment of a synthetic de-methylating module.
Chan WF, Coughlan HD, Chen Y, Keenan CR, Smyth GK, Perkins AC, Johanson TM, Allan RS.
Nat Commun. 2022 Sep 23;13(1):5582. doi: 10.1038/s41467-022-33181-4.
PubMed
Associated Plasmids |
A modular dCas9-based recruitment platform for combinatorial epigenome editing.
Swain T, Pflueger C, Freytag S, Poppe D, Pflueger J, Nguyen TV, Li JK, Lister R.
Nucleic Acids Res. 2023 Nov 24:gkad1108. doi: 10.1093/nar/gkad1108.
PubMed
Associated Plasmids |
Modular dual-color BiAD sensors for locus-specific readout of epigenome modifications in single cells.
Kohler AR, Hausser J, Harsch A, Bernhardt S, Haussermann L, Brenner LM, Lungu C, Olayioye MA, Bashtrykov P, Jeltsch A.
Cell Rep Methods. 2024 Mar 26:100739. doi: 10.1016/j.crmeth.2024.100739.
PubMed
Associated Plasmids |
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