pICE-HA-MRE11-WT Citations (5)
Originally described in: Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks.Chanut P, Britton S, Coates J, Jackson SP, Calsou P Nat Commun. 2016 Sep 19;7:12889. doi: 10.1038/ncomms12889. PubMed Journal
Articles Citing pICE-HA-MRE11-WT
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Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency. Mariggio G, Koch S, Zhang G, Weidner-Glunde M, Ruckert J, Kati S, Santag S, Schulz TF. PLoS Pathog. 2017 Apr 21;13(4):e1006335. doi: 10.1371/journal.ppat.1006335. eCollection 2017 Apr. PubMed |
MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends. Sharma S, Anand R, Zhang X, Francia S, Michelini F, Galbiati A, Williams H, Ronato DA, Masson JY, Rothenberg E, Cejka P, d'Adda di Fagagna F. Cell Rep. 2021 Jan 5;34(1):108565. doi: 10.1016/j.celrep.2020.108565. PubMed |
Yeast-based screening of cancer mutations in the DNA damage response protein Mre11 demonstrates importance of conserved capping domain residues. Harris C, Savas J, Ray S, Shanle EK. Mol Biol Rep. 2021 May;48(5):4107-4119. doi: 10.1007/s11033-021-06424-8. Epub 2021 Jun 1. PubMed |
Requirements for MRN endonuclease processing of topoisomerase II-mediated DNA damage in mammalian cells. Sun Y, Soans E, Mishina M, Petricci E, Pommier Y, Nitiss KC, Nitiss JL. Front Mol Biosci. 2022 Sep 23;9:1007064. doi: 10.3389/fmolb.2022.1007064. eCollection 2022. PubMed |
TRIM24 is critical for the cellular response to DNA double-strand breaks through regulating the recruitment of MRN complex. Wang Y, Yao Y, Wei Q, Long S, Chen Y, Xie J, Tan R, Jiang W, Zhang Q, Wu D, Xiao S, Wan F, Fu K. Oncogene. 2023 Feb;42(8):586-600. doi: 10.1038/s41388-022-02580-8. Epub 2022 Dec 22. PubMed |
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