AbVec1.1-IGKC Citations (19)
Originally described in: Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning.Tiller T, Meffre E, Yurasov S, Tsuiji M, Nussenzweig MC, Wardemann H J Immunol Methods. 2008 Jan 1;329(1-2):112-24. Epub 2007 Oct 31. PubMed Journal
Articles Citing AbVec1.1-IGKC
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Naive B Cells with High-Avidity Germline-Encoded Antigen Receptors Produce Persistent IgM(+) and Transient IgG(+) Memory B Cells. Pape KA, Maul RW, Dileepan T, Paustian AS, Gearhart PJ, Jenkins MK. Immunity. 2018 Jun 19;48(6):1135-1143.e4. doi: 10.1016/j.immuni.2018.04.019. Epub 2018 Jun 5. PubMed |
Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. Wong R, Belk JA, Govero J, Uhrlaub JL, Reinartz D, Zhao H, Errico JM, D'Souza L, Ripperger TJ, Nikolich-Zugich J, Shlomchik MJ, Satpathy AT, Fremont DH, Diamond MS, Bhattacharya D. Immunity. 2020 Nov 17;53(5):1078-1094.e7. doi: 10.1016/j.immuni.2020.09.001. Epub 2020 Oct 2. PubMed |
Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies. Doepker LE, Danon S, Harkins E, Ralph DK, Yaffe Z, Garrett ME, Dhar A, Wagner C, Stumpf MM, Arenz D, Williams JA, Jaoko W, Mandaliya K, Lee KK, Matsen FA 4th, Overbaugh JM. Elife. 2021 Jan 11;10. pii: 63444. doi: 10.7554/eLife.63444. PubMed |
Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies. Zhou D, Chan JF, Zhou B, Zhou R, Li S, Shan S, Liu L, Zhang AJ, Chen SJ, Chan CC, Xu H, Poon VK, Yuan S, Li C, Chik KK, Chan CC, Cao J, Chan CY, Kwan KY, Du Z, Lau TT, Zhang Q, Zhou J, To KK, Zhang L, Ho DD, Yuen KY, Chen Z. Cell Host Microbe. 2021 Apr 14;29(4):551-563.e5. doi: 10.1016/j.chom.2021.02.019. Epub 2021 Feb 25. PubMed |
Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms. Song E, Bartley CM, Chow RD, Ngo TT, Jiang R, Zamecnik CR, Dandekar R, Loudermilk RP, Dai Y, Liu F, Sunshine S, Liu J, Wu W, Hawes IA, Alvarenga BD, Huynh T, McAlpine L, Rahman NT, Geng B, Chiarella J, Goldman-Israelow B, Vogels CBF, Grubaugh ND, Casanovas-Massana A, Phinney BS, Salemi M, Alexander JR, Gallego JA, Lencz T, Walsh H, Wapniarski AE, Mohanty S, Lucas C, Klein J, Mao T, Oh J, Ring A, Spudich S, Ko AI, Kleinstein SH, Pak J, DeRisi JL, Iwasaki A, Pleasure SJ, Wilson MR, Farhadian SF. Cell Rep Med. 2021 May 18;2(5):100288. doi: 10.1016/j.xcrm.2021.100288. Epub 2021 May 3. PubMed |
A diverse collection of B cells responded to HIV infection in infant BG505. Simonich C, Shipley MM, Doepker L, Gobillot T, Garrett M, Cale EM, Hennessy B, Itell H, Chohan V, Doria-Rose N, Nduati R, Overbaugh J. Cell Rep Med. 2021 Jun 15;2(6):100314. doi: 10.1016/j.xcrm.2021.100314. eCollection 2021 Jun 15. PubMed |
Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection. Shipley MM, Mangala Prasad V, Doepker LE, Dingens A, Ralph DK, Harkins E, Dhar A, Arenz D, Chohan V, Weight H, Mandaliya K, Bloom JD, Matsen FA 4th, Lee KK, Overbaugh JM. Elife. 2021 Jul 15;10. pii: 68110. doi: 10.7554/eLife.68110. PubMed |
Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells. Song S, Manook M, Kwun J, Jackson AM, Knechtle SJ, Kelsoe G. Front Immunol. 2021 Jul 13;12:705140. doi: 10.3389/fimmu.2021.705140. eCollection 2021. PubMed |
Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Weber T, Potthoff J, Bizu S, Labuhn M, Dold L, Schoofs T, Horning M, Ercanoglu MS, Kreer C, Gieselmann L, Vanshylla K, Langhans B, Janicki H, Stroh LJ, Knops E, Nierhoff D, Spengler U, Kaiser R, Bjorkman PJ, Krey T, Bankwitz D, Pfeifer N, Pietschmann T, Flyak AI, Klein F. Immunity. 2022 Feb 8;55(2):341-354.e7. doi: 10.1016/j.immuni.2021.12.003. Epub 2022 Jan 5. PubMed |
SpySwitch enables pH- or heat-responsive capture and release for plug-and-display nanoassembly.
Vester SK, Rahikainen R, Khairil Anuar INA, Hills RA, Tan TK, Howarth M.
Nat Commun. 2022 Jun 28;13(1):3714. doi: 10.1038/s41467-022-31193-8.
PubMed
Associated Plasmids |
Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Pushparaj P, Nicoletto A, Sheward DJ, Das H, Castro Dopico X, Perez Vidakovics L, Hanke L, Chernyshev M, Narang S, Kim S, Fischbach J, Ekstrom S, McInerney G, Hallberg BM, Murrell B, Corcoran M, Karlsson Hedestam GB. Immunity. 2023 Jan 10;56(1):193-206.e7. doi: 10.1016/j.immuni.2022.12.005. Epub 2022 Dec 12. PubMed |
Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies. Oludada OE, Costa G, Burn Aschner C, Obraztsova AS, Prieto K, Canetta C, Hoffman SL, Kremsner PG, Mordmuller B, Murugan R, Julien JP, Levashina EA, Wardemann H. EMBO Mol Med. 2023 Jun 7;15(6):e17454. doi: 10.15252/emmm.202317454. Epub 2023 Apr 21. PubMed |
Reconstruction of a polyclonal ADCC antibody repertoire from an HIV-1 non-transmitting mother. Yaffe ZA, Ding S, Sung K, Chohan V, Marchitto L, Doepker L, Ralph D, Nduati R, Matsen FA 4th, Finzi A, Overbaugh J. iScience. 2023 Apr 26;26(5):106762. doi: 10.1016/j.isci.2023.106762. eCollection 2023 May 19. PubMed |
Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy. Marone R, Landmann E, Devaux A, Lepore R, Seyres D, Zuin J, Burgold T, Engdahl C, Capoferri G, Dell'Aglio A, Larrue C, Simonetta F, Rositzka J, Rhiel M, Andrieux G, Gallagher DN, Schroder MS, Wiederkehr A, Sinopoli A, Do Sacramento V, Haydn A, Garcia-Prat L, Divsalar C, Camus A, Xu L, Bordoli L, Schwede T, Porteus M, Tamburini J, Corn JE, Cathomen T, Cornu TI, Urlinger S, Jeker LT. J Exp Med. 2023 Dec 4;220(12):e20231235. doi: 10.1084/jem.20231235. Epub 2023 Sep 29. PubMed |
Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted. Acar DD, Witkowski W, Wejda M, Wei R, Desmet T, Schepens B, De Cae S, Sedeyn K, Eeckhaut H, Fijalkowska D, Roose K, Vanmarcke S, Poupon A, Jochmans D, Zhang X, Abdelnabi R, Foo CS, Weynand B, Reiter D, Callewaert N, Remaut H, Neyts J, Saelens X, Gerlo S, Vandekerckhove L. EBioMedicine. 2024 Feb;100:104960. doi: 10.1016/j.ebiom.2023.104960. Epub 2024 Jan 16. PubMed |
Physics-driven structural docking and protein language models accelerate antibody screening and design for broad-spectrum antiviral therapy. Almubarak HF, Tan W, Hoffmann AD, Wei J, El-Shennawy L, Squires JR, Sun Y, Dashzeveg NK, Simonton B, Jia Y, Iyer R, Xu Y, Nicolaescu V, Elli D, Randall GC, Schipma MJ, Swaminathan S, Ison MG, Liu H, Fang D, Shen Y. bioRxiv [Preprint]. 2024 Mar 4:2024.03.01.582176. doi: 10.1101/2024.03.01.582176. PubMed |
Rapid generation of human recombinant monoclonal antibodies from antibody-secreting cells using ferrofluid-based technology. Strazza V, Rossi M, Avati A, Tiseo G, Falcone M, Cusi MG, Menichetti F, Ricciardi-Castagnoli P, Tinti C, Pileri P. Front Immunol. 2024 Apr 18;15:1341389. doi: 10.3389/fimmu.2024.1341389. eCollection 2024. PubMed |
Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers. Verma S, Dufort MJ, Olsen TM, Kimmel S, Labuda JC, Scharffenberger S, McGuire AT, Harrison OJ. Immunity. 2024 Jun 11;57(6):1428-1441.e8. doi: 10.1016/j.immuni.2024.04.014. Epub 2024 May 8. PubMed |
Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies. Sheward DJ, Pushparaj P, Das H, Greaney AJ, Kim C, Kim S, Hanke L, Hyllner E, Dyrdak R, Lee J, Dopico XC, Dosenovic P, Peacock TP, McInerney GM, Albert J, Corcoran M, Bloom JD, Murrell B, Karlsson Hedestam GB, Hallberg BM. Cell Rep Med. 2024 Jun 18;5(6):101577. doi: 10.1016/j.xcrm.2024.101577. Epub 2024 May 17. PubMed |
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