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pLV-TetO-hNGN2-eGFP-Puro Citations (17)

Originally described in: Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells.
Ho SM, Hartley BJ, Tcw J, Beaumont M, Stafford K, Slesinger PA, Brennand KJ Methods. 2015 Nov 25. pii: S1046-2023(15)30159-6. doi: 10.1016/j.ymeth.2015.11.019. PubMed Journal

Articles Citing pLV-TetO-hNGN2-eGFP-Puro

Articles
Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes. Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ. Stem Cell Reports. 2017 Aug 8;9(2):615-628. doi: 10.1016/j.stemcr.2017.06.012. Epub 2017 Jul 27. PubMed

Associated Plasmids
mTOR and autophagy pathways are dysregulated in murine and human models of Schaaf-Yang syndrome. Crutcher E, Pal R, Naini F, Zhang P, Laugsch M, Kim J, Bajic A, Schaaf CP. Sci Rep. 2019 Nov 4;9(1):15935. doi: 10.1038/s41598-019-52287-2. PubMed
Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models. Gregory JA, Hoelzli E, Abdelaal R, Braine C, Cuevas M, Halpern M, Barretto N, Schrode N, Akbalik G, Kang K, Cheng E, Bowles K, Lotz S, Goderie S, Karch CM, Temple S, Goate A, Brennand KJ, Phatnani H. Cells. 2020 Jun 5;9(6). pii: cells9061406. doi: 10.3390/cells9061406. PubMed

Associated Plasmids
Rapid generation of regionally specified CNS neurons by sequential patterning and conversion of human induced pluripotent stem cells. Chen M, Maimaitili M, Habekost M, Gill KP, Mermet-Joret N, Nabavi S, Febbraro F, Denham M. Stem Cell Res. 2020 Oct;48:101945. doi: 10.1016/j.scr.2020.101945. Epub 2020 Aug 3. PubMed
Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production. Chen H, Victor AK, Klein J, Tacer KF, Tai DJ, de Esch C, Nuttle A, Temirov J, Burnett LC, Rosenbaum M, Zhang Y, Ding L, Moresco JJ, Diedrich JK, Yates JR 3rd, Tillman HS, Leibel RL, Talkowski ME, Billadeau DD, Reiter LT, Potts PR. JCI Insight. 2020 Sep 3;5(17). pii: 138576. doi: 10.1172/jci.insight.138576. PubMed
Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons. Hulme AJ, McArthur JR, Maksour S, Miellet S, Ooi L, Adams DJ, Finol-Urdaneta RK, Dottori M. Front Cell Neurosci. 2020 Dec 4;14:600895. doi: 10.3389/fncel.2020.600895. eCollection 2020. PubMed
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk. Powell SK, O'Shea C, Townsley K, Prytkova I, Dobrindt K, Elahi R, Iskhakova M, Lambert T, Valada A, Liao W, Ho SM, Slesinger PA, Huckins LM, Akbarian S, Brennand KJ. Mol Psychiatry. 2021 Sep 7. pii: 10.1038/s41380-021-01273-0. doi: 10.1038/s41380-021-01273-0. PubMed

Associated Plasmids
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE varepsilon2 for Alzheimer's disease. Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W, Bennett DA, Foroud TM, Wang LS, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Au R, Lunetta KL, Ikezu T, Stein TD, Farrer LA. Alzheimers Dement. 2022 Nov;18(11):2042-2054. doi: 10.1002/alz.12607. Epub 2022 Feb 9. PubMed
Selective ferroptosis vulnerability due to familial Alzheimer's disease presenilin mutations. Greenough MA, Lane DJR, Balez R, Anastacio HTD, Zeng Z, Ganio K, McDevitt CA, Acevedo K, Belaidi AA, Koistinaho J, Ooi L, Ayton S, Bush AI. Cell Death Differ. 2022 Apr 21. pii: 10.1038/s41418-022-01003-1. doi: 10.1038/s41418-022-01003-1. PubMed
The mitochondrial RNA granule modulates manganese-dependent cell toxicity. Werner E, Gokhale A, Ackert M, Xu C, Wen Z, Roberts AM, Roberts BR, Vrailas-Mortimer A, Crocker A, Faundez V. Mol Biol Cell. 2022 Oct 1;33(12):ar108. doi: 10.1091/mbc.E22-03-0096. Epub 2022 Aug 3. PubMed
Comparative chromatin accessibility upon BDNF stimulation delineates neuronal regulatory elements. Ibarra IL, Ratnu VS, Gordillo L, Hwang IY, Mariani L, Weinand K, Hammaren HM, Heck J, Bulyk ML, Savitski MM, Zaugg JB, Noh KM. Mol Syst Biol. 2022 Aug;18(8):e10473. doi: 10.15252/msb.202110473. PubMed
A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility. Voloudakis G, Vicari JM, Venkatesh S, Hoffman GE, Dobrindt K, Zhang W, Beckmann ND, Higgins CA, Argyriou S, Jiang S, Hoagland D, Gao L, Corvelo A, Cho K, Lee KM, Bian J, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Lynch JA, Merad M, tenOever BR, Charney AW, Brennand KJ, Fullard JF, Roussos P. NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038/s41525-022-00324-x. PubMed
Hominoid SVA-lncRNA AK057321 targets human-specific SVA retrotransposons in SCN8A and CDK5RAP2 to initiate neuronal maturation. Nadler MJS, Chang W, Ozkaynak E, Huo Y, Nong Y, Boillot M, Johnson M, Moreno A, Matthew P Anderson. Commun Biol. 2023 Mar 30;6(1):347. doi: 10.1038/s42003-023-04683-8. PubMed

Associated Plasmids
Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes. Powell SK, Liao W, O'Shea C, Kammourh S, Ghorbani S, Rigat R, Elahi R, Deans PM, Le DJ, Agarwal P, Seow WQ, Wang KC, Akbarian S, Brennand KJ. bioRxiv. 2023 Jul 19:2023.07.17.549339. doi: 10.1101/2023.07.17.549339. Preprint. PubMed
Defined co-cultures of glutamatergic and GABAergic neurons with a mutation in DISC1 reveal aberrant phenotypes in GABAergic neurons. Heider J, Stahl A, Sperlich D, Hartmann SM, Vogel S, Breitmeyer R, Templin M, Volkmer H. BMC Neurosci. 2024 Mar 4;25(1):12. doi: 10.1186/s12868-024-00858-z. PubMed
Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons. Hees JT, Wanderoy S, Lindner J, Helms M, Murali Mahadevan H, Harbauer AB. Nat Metab. 2024 Mar;6(3):514-530. doi: 10.1038/s42255-024-01007-w. Epub 2024 Mar 19. PubMed
CRISPR-Cas9 editing of synaptic genes in human embryonic stem cells for functional analysis in induced human neurons. Houcek A, Ma ZZ, Trauterman B, Uzay B, Monteggia LM, Kavalali ET. STAR Protoc. 2024 Jun 21;5(2):103089. doi: 10.1016/j.xpro.2024.103089. Epub 2024 May 24. PubMed

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