Skip to main content
Addgene

pcDNA3.1_pCMV-nCas-PmCDA1-ugi pH1-gRNA(HPRT) Citations (15)

Originally described in: Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems.
Nishida K, Arazoe T, Yachie N, Banno S, Kakimoto M, Tabata M, Mochizuki M, Miyabe A, Araki M, Hara KY, Shimatani Z, Kondo A Science. 2016 Aug 4. pii: aaf8729. PubMed Journal

Articles Citing pcDNA3.1_pCMV-nCas-PmCDA1-ugi pH1-gRNA(HPRT)

Articles
Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity. Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR. Sci Adv. 2017 Aug 30;3(8):eaao4774. doi: 10.1126/sciadv.aao4774. eCollection 2017 Aug. PubMed

Associated Plasmids
Development of a genetic sensor that eliminates p53 deficient cells. Mircetic J, Dietrich A, Paszkowski-Rogacz M, Krause M, Buchholz F. Nat Commun. 2017 Nov 13;8(1):1463. doi: 10.1038/s41467-017-01688-w. PubMed
Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID. Sasaguri H, Nagata K, Sekiguchi M, Fujioka R, Matsuba Y, Hashimoto S, Sato K, Kurup D, Yokota T, Saido TC. Nat Commun. 2018 Jul 24;9(1):2892. doi: 10.1038/s41467-018-05262-w. PubMed
Intrinsic Nucleotide Preference of Diversifying Base Editors Guides Antibody Ex Vivo Affinity Maturation. Liu LD, Huang M, Dai P, Liu T, Fan S, Cheng X, Zhao Y, Yeap LS, Meng FL. Cell Rep. 2018 Oct 23;25(4):884-892.e3. doi: 10.1016/j.celrep.2018.09.090. PubMed

Associated Plasmids
Screening of CRISPR/Cas base editors to target the AMD high-risk Y402H complement factor H variant. Tran MTN, Khalid MKNM, Pebay A, Cook AL, Liang HH, Wong RCB, Craig JE, Liu GS, Hung SS, Hewitt AW. Mol Vis. 2019 Mar 16;25:174-182. eCollection 2019. PubMed
CRISPR DNA base editors with reduced RNA off-target and self-editing activities. Grunewald J, Zhou R, Iyer S, Lareau CA, Garcia SP, Aryee MJ, Joung JK. Nat Biotechnol. 2019 Sep 2. pii: 10.1038/s41587-019-0236-6. doi: 10.1038/s41587-019-0236-6. PubMed

Associated Plasmids
Base editors for simultaneous introduction of C-to-T and A-to-G mutations. Sakata RC, Ishiguro S, Mori H, Tanaka M, Tatsuno K, Ueda H, Yamamoto S, Seki M, Masuyama N, Nishida K, Nishimasu H, Arakawa K, Kondo A, Nureki O, Tomita M, Aburatani H, Yachie N. Nat Biotechnol. 2020 Jun 1. pii: 10.1038/s41587-020-0509-0. doi: 10.1038/s41587-020-0509-0. PubMed

Associated Plasmids
Gene-specific mutagenesis enables rapid continuous evolution of enzymes in vivo. Park H, Kim S. Nucleic Acids Res. 2021 Apr 6;49(6):e32. doi: 10.1093/nar/gkaa1231. PubMed

Associated Plasmids
The integrity of the U12 snRNA 3' stem-loop is necessary for its overall stability. Norppa AJ, Frilander MJ. Nucleic Acids Res. 2021 Mar 18;49(5):2835-2847. doi: 10.1093/nar/gkab048. PubMed
The efficacy of CRISPR-mediated cytosine base editing with the RPS5a promoter in Arabidopsis thaliana. Choi M, Yun JY, Kim JH, Kim JS, Kim ST. Sci Rep. 2021 Apr 13;11(1):8087. doi: 10.1038/s41598-021-87669-y. PubMed
Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope. Villiger L, Schmidheini L, Mathis N, Rothgangl T, Marquart K, Schwank G. Mol Ther Nucleic Acids. 2021 Aug 26;26:502-510. doi: 10.1016/j.omtn.2021.08.025. eCollection 2021 Dec 3. PubMed

Associated Plasmids
Target-AID-Mediated Multiplex Base Editing in Porcine Fibroblasts. Yum SY, Jang G, Koo O. Animals (Basel). 2021 Dec 16;11(12). pii: ani11123570. doi: 10.3390/ani11123570. PubMed
In Vivo Rapid Investigation of CRISPR-Based Base Editing Components in Escherichia coli (IRI-CCE): A Platform for Evaluating Base Editing Tools and Their Components. Shelake RM, Pramanik D, Kim JY. Int J Mol Sci. 2022 Jan 20;23(3). pii: ijms23031145. doi: 10.3390/ijms23031145. PubMed
A framework to efficiently describe and share reproducible DNA materials and construction protocols. Mori H, Yachie N. Nat Commun. 2022 May 24;13(1):2894. doi: 10.1038/s41467-022-30588-x. PubMed
Improved Dual Base Editor Systems (iACBEs) for Simultaneous Conversion of Adenine and Cytosine in the Bacterium Escherichia coli. Shelake RM, Pramanik D, Kim JY. mBio. 2023 Feb 28;14(1):e0229622. doi: 10.1128/mbio.02296-22. Epub 2023 Jan 10. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.