pU6-As-crRNA Citations (5)

Originally described in: Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells.
Kim D, Kim J, Hur JK, Been KW, Yoon SH, Kim JS Nat Biotechnol. 2016 Jun 6. doi: 10.1038/nbt.3609. PubMed Journal

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Articles Citing pU6-As-crRNA

Articles
Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1. Kweon J, Jang AH, Kim DE, Yang JW, Yoon M, Rim Shin H, Kim JS, Kim Y. Nat Commun. 2017 Nov 23;8(1):1723. doi: 10.1038/s41467-017-01650-w. PubMed
The Acidaminococcus sp. Cas12a nuclease recognizes GTTV and GCTV as non-canonical PAMs. Jacobsen T, Liao C, Beisel CL. FEMS Microbiol Lett. 2019 Apr 1;366(8). pii: 5475644. doi: 10.1093/femsle/fnz085. PubMed
Specificity profiling of CRISPR system reveals greatly enhanced off-target gene editing. Wang Y, Wang M, Zheng T, Hou Y, Zhang P, Tang T, Wei J, Du Q. Sci Rep. 2020 Feb 10;10(1):2269. doi: 10.1038/s41598-020-58627-x. PubMed
Characterization of Cas12a nucleases reveals diverse PAM profiles between closely-related orthologs. Jacobsen T, Ttofali F, Liao C, Manchalu S, Gray BN, Beisel CL. Nucleic Acids Res. 2020 Jun 4;48(10):5624-5638. doi: 10.1093/nar/gkaa272. PubMed
Engineering of Cas12a nuclease variants with enhanced genome-editing specificity. Chen P, Zhou J, Liu H, Zhou E, He B, Wu Y, Wang H, Sun Z, Paek C, Lei J, Chen Y, Zhang X, Yin L. PLoS Biol. 2024 Mar 14;22(3):e3002514. doi: 10.1371/journal.pbio.3002514. eCollection 2024 Mar. PubMed

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