pcDNA3-N-HA-NEK7 Citations (5)

Originally described in: NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, Su L, Pratt D, Bu CH, Hildebrand S, Lyon S, Scott L, Quan J, Sun Q, Russell J, Arnett S, Jurek P, Chen D, Kravchenko VV, Mathison JC, Moresco EM, Monson NL, Ulevitch RJ, Beutler B Nat Immunol. 2016 Mar;17(3):250-8. doi: 10.1038/ni.3333. Epub 2015 Dec 7. PubMed Journal

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Articles Citing pcDNA3-N-HA-NEK7

Articles
Reconstruction of the Mouse Inflammasome System in HEK293T Cells. Shi H, Murray A, Beutler B. Bio Protoc. 2016 Nov 5;6(21). pii: e1986. doi: 10.21769/BioProtoc.1986. PubMed
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway. Hafner-Bratkovic I, Susjan P, Lainscek D, Tapia-Abellan A, Cerovic K, Kadunc L, Angosto-Bazarra D, Pelegrin P, Jerala R. Nat Commun. 2018 Dec 5;9(1):5182. doi: 10.1038/s41467-018-07573-4. PubMed
Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation. Hughes MM, Hooftman A, Angiari S, Tummala P, Zaslona Z, Runtsch MC, McGettrick AF, Sutton CE, Diskin C, Rooke M, Takahashi S, Sundararaj S, Casarotto MG, Dahlstrom JE, Palsson-McDermott EM, Corr SC, Mills KHG, Preston RJS, Neamati N, Xie Y, Baell JB, Board PG, O'Neill LAJ. Cell Rep. 2019 Oct 1;29(1):151-161.e5. doi: 10.1016/j.celrep.2019.08.072. PubMed
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation. Hooftman A, Angiari S, Hester S, Corcoran SE, Runtsch MC, Ling C, Ruzek MC, Slivka PF, McGettrick AF, Banahan K, Hughes MM, Irvine AD, Fischer R, O'Neill LAJ. Cell Metab. 2020 Sep 1;32(3):468-478.e7. doi: 10.1016/j.cmet.2020.07.016. Epub 2020 Aug 12. PubMed
The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis. Hsu CG, Chavez CL, Zhang C, Sowden M, Yan C, Berk BC. Cell Death Differ. 2022 Sep;29(9):1790-1803. doi: 10.1038/s41418-022-00966-5. Epub 2022 Mar 9. PubMed

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