pcDNA3-N-Flag-NLRP3 Citations (12)

Originally described in: NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, Su L, Pratt D, Bu CH, Hildebrand S, Lyon S, Scott L, Quan J, Sun Q, Russell J, Arnett S, Jurek P, Chen D, Kravchenko VV, Mathison JC, Moresco EM, Monson NL, Ulevitch RJ, Beutler B Nat Immunol. 2016 Mar;17(3):250-8. doi: 10.1038/ni.3333. Epub 2015 Dec 7. PubMed Journal

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Articles Citing pcDNA3-N-Flag-NLRP3

Articles
Reconstruction of the Mouse Inflammasome System in HEK293T Cells. Shi H, Murray A, Beutler B. Bio Protoc. 2016 Nov 5;6(21). pii: e1986. doi: 10.21769/BioProtoc.1986. PubMed
The pore-forming subunit Kir6.1 of the K-ATP channel negatively regulates the NLRP3 inflammasome to control insulin resistance by interacting with NLRP3. Du RH, Lu M, Wang C, Ding JH, Wu G, Hu G. Exp Mol Med. 2019 Aug 6;51(8):92. doi: 10.1038/s12276-019-0291-6. PubMed
Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation. Hughes MM, Hooftman A, Angiari S, Tummala P, Zaslona Z, Runtsch MC, McGettrick AF, Sutton CE, Diskin C, Rooke M, Takahashi S, Sundararaj S, Casarotto MG, Dahlstrom JE, Palsson-McDermott EM, Corr SC, Mills KHG, Preston RJS, Neamati N, Xie Y, Baell JB, Board PG, O'Neill LAJ. Cell Rep. 2019 Oct 1;29(1):151-161.e5. doi: 10.1016/j.celrep.2019.08.072. PubMed
Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis). Christgen S, Zheng M, Kesavardhana S, Karki R, Malireddi RKS, Banoth B, Place DE, Briard B, Sharma BR, Tuladhar S, Samir P, Burton A, Kanneganti TD. Front Cell Infect Microbiol. 2020 May 29;10:237. doi: 10.3389/fcimb.2020.00237. eCollection 2020. PubMed
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation. Hooftman A, Angiari S, Hester S, Corcoran SE, Runtsch MC, Ling C, Ruzek MC, Slivka PF, McGettrick AF, Banahan K, Hughes MM, Irvine AD, Fischer R, O'Neill LAJ. Cell Metab. 2020 Sep 1;32(3):468-478.e7. doi: 10.1016/j.cmet.2020.07.016. Epub 2020 Aug 12. PubMed
NLRP3 Blockade Suppresses Pro-Inflammatory and Pro-Angiogenic Cytokine Secretion in Diabetic Retinopathy. Chai G, Liu S, Yang H, Du G, Chen X. Diabetes Metab Syndr Obes. 2020 Aug 25;13:3047-3058. doi: 10.2147/DMSO.S264215. eCollection 2020. PubMed
The Human-Specific STING Agonist G10 Activates Type I Interferon and the NLRP3 Inflammasome in Porcine Cells. Ming SL, Zeng L, Guo YK, Zhang S, Li GL, Ma YX, Zhai YY, Chang WR, Yang L, Wang J, Yang GY, Chu BB. Front Immunol. 2020 Sep 24;11:575818. doi: 10.3389/fimmu.2020.575818. eCollection 2020. PubMed
The lipid peroxidation product 4-hydroxynonenal inhibits NLRP3 inflammasome activation and macrophage pyroptosis. Hsu CG, Chavez CL, Zhang C, Sowden M, Yan C, Berk BC. Cell Death Differ. 2022 Sep;29(9):1790-1803. doi: 10.1038/s41418-022-00966-5. Epub 2022 Mar 9. PubMed
Toxoplasma gondii Rhoptry Protein 7 (ROP7) Interacts with NLRP3 and Promotes Inflammasome Hyperactivation in THP-1-Derived Macrophages. Zhu L, Qi W, Yang G, Yang Y, Wang Y, Zheng L, Fu Y, Cheng X. Cells. 2022 May 12;11(10). pii: cells11101630. doi: 10.3390/cells11101630. PubMed
SARS-COV-2 viroporins activate the NLRP3-inflammasome by the mitochondrial permeability transition pore. Guarnieri JW, Angelin A, Murdock DG, Schaefer P, Portluri P, Lie T, Huang J, Wallace DC. Front Immunol. 2023 Feb 20;14:1064293. doi: 10.3389/fimmu.2023.1064293. eCollection 2023. PubMed
Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. Xu Y, Xu Y, Biby S, Kaur B, Liu Y, Bagdasarian FA, Wey HY, Tanzi R, Zhang C, Wang C, Zhang S. J Med Chem. 2024 Jan 11;67(1):555-571. doi: 10.1021/acs.jmedchem.3c01782. Epub 2023 Dec 27. PubMed
NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation. Yu T, Hou D, Zhao J, Lu X, Greentree WK, Zhao Q, Yang M, Conde DG, Linder ME, Lin H. Cell Rep. 2024 Apr 23;43(4):114070. doi: 10.1016/j.celrep.2024.114070. Epub 2024 Apr 6. PubMed

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