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Addgene

MSCB-hDot1Lwt Citations (4)

Originally described in: hDOT1L links histone methylation to leukemogenesis.
Okada Y, Feng Q, Lin Y, Jiang Q, Li Y, Coffield VM, Su L, Xu G, Zhang Y Cell. 2005 Apr 22;121(2):167-78.
PubMed Journal

Articles Citing MSCB-hDot1Lwt

Articles
Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L. Worden EJ, Hoffmann NA, Hicks CW, Wolberger C. Cell. 2019 Feb 8. pii: S0092-8674(19)30151-5. doi: 10.1016/j.cell.2019.02.002. PubMed

Associated Plasmids

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer. Vatapalli R, Sagar V, Rodriguez Y, Zhao JC, Unno K, Pamarthy S, Lysy B, Anker J, Han H, Yoo YA, Truica M, Chalmers ZR, Giles F, Yu J, Chakravarti D, Carneiro B, Abdulkadir SA. Nat Commun. 2020 Aug 19;11(1):4153. doi: 10.1038/s41467-020-18013-7. PubMed
SUMOylation inhibition enhances multiple myeloma sensitivity to lenalidomide. Du L, Liu W, Pichiorri F, Rosen ST. Cancer Gene Ther. 2022 Mar 25. pii: 10.1038/s41417-022-00450-9. doi: 10.1038/s41417-022-00450-9. PubMed
The DNA damage-independent ATM signalling maintains CBP/DOT1L axis in MLL rearranged acute myeloid leukaemia. Wang G, Zhang W, Ren J, Zeng Y, Dang X, Tian X, Yu W, Li Z, Ma Y, Yang P, Lu J, Zheng J, Lu B, Xu J, Liang A. Oncogene. 2024 Jun;43(25):1900-1916. doi: 10.1038/s41388-024-02998-2. Epub 2024 Apr 26. PubMed

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