pEGFP-hGal3 Citations (23)
Originally described in: Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury.Maejima I, Takahashi A, Omori H, Kimura T, Takabatake Y, Saitoh T, Yamamoto A, Hamasaki M, Noda T, Isaka Y, Yoshimori T EMBO J. 2013 Aug 28;32(17):2336-47. doi: 10.1038/emboj.2013.171. Epub 2013 Aug 6. PubMed Journal
Articles Citing pEGFP-hGal3
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| Lysophagy: A Method for Monitoring Lysosomal Rupture Followed by Autophagy-Dependent Recovery. Otomo T, Yoshimori T. Methods Mol Biol. 2017;1594:141-149. doi: 10.1007/978-1-4939-6934-0_8. PubMed |
| A genome-wide CRISPR screen reconciles the role of N-linked glycosylation in galectin-3 transport to the cell surface. Stewart SE, Menzies SA, Popa SJ, Savinykh N, Petrunkina Harrison A, Lehner PJ, Moreau K. J Cell Sci. 2017 Oct 1;130(19):3234-3247. doi: 10.1242/jcs.206425. Epub 2017 Aug 3. PubMed |
| Lysosomotropism depends on glucose: a chloroquine resistance mechanism. Gallagher LE, Radhi OA, Abdullah MO, McCluskey AG, Boyd M, Chan EYW. Cell Death Dis. 2017 Aug 24;8(8):e3014. doi: 10.1038/cddis.2017.416. PubMed |
| The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Gaidt MM, Ebert TS, Chauhan D, Ramshorn K, Pinci F, Zuber S, O'Duill F, Schmid-Burgk JL, Hoss F, Buhmann R, Wittmann G, Latz E, Subklewe M, Hornung V. Cell. 2017 Nov 16;171(5):1110-1124.e18. doi: 10.1016/j.cell.2017.09.039. Epub 2017 Oct 12. PubMed |
| Distinct cargo-specific response landscapes underpin the complex and nuanced role of galectin-glycan interactions in clathrin-independent endocytosis. Mathew MP, Donaldson JG. J Biol Chem. 2018 May 11;293(19):7222-7237. doi: 10.1074/jbc.RA118.001802. Epub 2018 Mar 26. PubMed |
| Activation of the macroautophagy pathway by Yersinia enterocolitica promotes intracellular multiplication and egress of yersiniae from epithelial cells. Valencia Lopez MJ, Schimmeck H, Gropengiesser J, Middendorf L, Quitmann M, Schneider C, Holstermann B, Wacker R, Heussler V, Reimer R, Aepfelbacher M, Ruckdeschel K. Cell Microbiol. 2019 May 17:e13046. doi: 10.1111/cmi.13046. PubMed |
| Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death. Radhi OA, Davidson S, Scott F, Zeng RX, Jones DH, Tomkinson NCO, Yu J, Chan EYW. J Biol Chem. 2019 Sep 27;294(39):14289-14307. doi: 10.1074/jbc.RA119.008923. Epub 2019 Aug 6. PubMed |
Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation.
Chen JJ, Nathaniel DL, Raghavan P, Nelson M, Tian R, Tse E, Hong JY, See SK, Mok SA, Hein MY, Southworth DR, Grinberg LT, Gestwicki JE, Leonetti MD, Kampmann M.
J Biol Chem. 2019 Oct 2. pii: RA119.009432. doi: 10.1074/jbc.RA119.009432.
PubMed
Associated Plasmids |
| LRRK2 activation controls the repair of damaged endomembranes in macrophages. Herbst S, Campbell P, Harvey J, Bernard EM, Papayannopoulos V, Wood NW, Morris HR, Gutierrez MG. EMBO J. 2020 Sep 15;39(18):e104494. doi: 10.15252/embj.2020104494. Epub 2020 Jul 9. PubMed |
| LZ-106, a potent lysosomotropic agent, causing TFEB-dependent cytoplasmic vacuolization. Zou X, Meng F, Fu C, Zhou J, Zhang Y, Wang R, Zhang C, Li Z, Guo Q, Yang L. Gene. 2020 Nov 15;760:145017. doi: 10.1016/j.gene.2020.145017. Epub 2020 Aug 2. PubMed |
LRRK2 mediates tubulation and vesicle sorting from lysosomes.
Bonet-Ponce L, Beilina A, Williamson CD, Lindberg E, Kluss JH, Saez-Atienzar S, Landeck N, Kumaran R, Mamais A, Bleck CKE, Li Y, Cookson MR.
Sci Adv. 2020 Nov 11;6(46). pii: 6/46/eabb2454. doi: 10.1126/sciadv.abb2454. Print 2020 Nov.
PubMed
Associated Plasmids |
| Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth. Gupta S, Yano J, Mercier V, Htwe HH, Shin HR, Rademaker G, Cakir Z, Ituarte T, Wen KW, Kim GE, Zoncu R, Roux A, Dawson DW, Perera RM. Nat Cell Biol. 2021 Mar;23(3):232-242. doi: 10.1038/s41556-021-00644-7. Epub 2021 Mar 8. PubMed |
| A Vaspin-HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease. Nakatsuka A, Yamaguchi S, Eguchi J, Kakuta S, Iwakura Y, Sugiyama H, Wada J. Commun Biol. 2021 Mar 19;4(1):373. doi: 10.1038/s42003-021-01902-y. PubMed |
| SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance. Liu K, Kong L, Graham DB, Carey KL, Xavier RJ. Cell Rep. 2021 Jul 27;36(4):109434. doi: 10.1016/j.celrep.2021.109434. PubMed |
| Leucine retention in lysosomes is regulated by starvation. Bandyopadhyay U, Todorova P, Pavlova NN, Tada Y, Thompson CB, Finley LWS, Overholtzer M. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6). pii: 2114912119. doi: 10.1073/pnas.2114912119. PubMed |
| Nutrient-responsive O-GlcNAcylation dynamically modulates the secretion of glycan-binding protein galectin 3. Mathew MP, Abramowitz LK, Donaldson JG, Hanover JA. J Biol Chem. 2022 Mar;298(3):101743. doi: 10.1016/j.jbc.2022.101743. Epub 2022 Feb 17. PubMed |
| Live imaging of Yersinia translocon formation and immune recognition in host cells. Rudolph M, Carsten A, Kulnik S, Aepfelbacher M, Wolters M. PLoS Pathog. 2022 May 23;18(5):e1010251. doi: 10.1371/journal.ppat.1010251. eCollection 2022 May. PubMed |
| Therapeutic advantage of targeting lysosomal membrane integrity supported by lysophagy in malignant glioma. Jing Y, Kobayashi M, Vu HT, Kasahara A, Chen X, Pham LT, Kurayoshi K, Tadokoro Y, Ueno M, Todo T, Nakada M, Hirao A. Cancer Sci. 2022 Aug;113(8):2716-2726. doi: 10.1111/cas.15451. Epub 2022 Jun 27. PubMed |
| Lysosomal lipid peroxidation regulates tumor immunity. Bhardwaj M, Lee JJ, Versace AM, Harper SL, Goldman AR, Crissey MAS, Jain V, Singh MP, Vernon M, Aplin AE, Lee S, Morita M, Winkler JD, Liu Q, Speicher DW, Amaravadi RK. J Clin Invest. 2023 Apr 17;133(8):e164596. doi: 10.1172/JCI164596. PubMed |
| An ATG12-ATG5-TECPR1 E3-like complex regulates unconventional LC3 lipidation at damaged lysosomes. Corkery DP, Castro-Gonzalez S, Knyazeva A, Herzog LK, Wu YW. EMBO Rep. 2023 Sep 6;24(9):e56841. doi: 10.15252/embr.202356841. Epub 2023 Jun 29. PubMed |
| Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence. Soha SA, Santhireswaran A, Huq S, Casimir-Powell J, Jenkins N, Hodgson GK, Sugiyama M, Antonescu CN, Impellizzeri S, Botelho RJ. Mol Biol Cell. 2023 Sep 1;34(10):ar96. doi: 10.1091/mbc.E22-06-0200. Epub 2023 Jul 5. PubMed |
| Mechano-dependent sorbitol accumulation supports biomolecular condensate. Torrino S, Oldham WM, Tejedor AR, Burgos IS, Rachedi N, Fraissard K, Chauvet C, Sbai C, O'Hara BP, Abelanet S, Brau F, Clavel S, Collepardo-Guevara R, Espinosa JR, Ben-Sahra I, Bertero T. bioRxiv [Preprint]. 2023 Jul 25:2023.07.24.550444. doi: 10.1101/2023.07.24.550444. PubMed |
| Co-expression of galectin-3 and vimentin in triple negative breast cancer cells promotes tumor progression, metastasis and survival. Jeethy Ram T, Lekshmi A, Darvin P, Rajappan P, Jagathnath Krishna KM, Anoop TM, Augustine P, Mathew AP, Cherian K, Bhargavan RV, Somanathan T, Radhakrishna Pillai M, Santhosh Kumar TR, Sujathan K. Tumour Biol. 2023;45(1):31-54. doi: 10.3233/TUB-230002. PubMed |
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