plentiCRISPR-sgGOT1 Citations (2)
Originally described in: An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.Birsoy K, Wang T, Chen WW, Freinkman E, Abu-Remaileh M, Sabatini DM Cell. 2015 Jul 30;162(3):540-51. doi: 10.1016/j.cell.2015.07.016. PubMed Journal
Articles Citing plentiCRISPR-sgGOT1
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Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. Kang YP, Torrente L, Falzone A, Elkins CM, Liu M, Asara JM, Dibble CC, DeNicola GM. Elife. 2019 May 20;8. pii: 45572. doi: 10.7554/eLife.45572. PubMed |
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA. Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2. PubMed |
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