pCI SMN2 Citations (6)
Originally described in: A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy.Lorson CL, Hahnen E, Androphy EJ, Wirth B Proc Natl Acad Sci U S A. 1999 May 25;96(11):6307-11. PubMed
Articles Citing pCI SMN2
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| Mechanistic studies of a small-molecule modulator of SMN2 splicing. Wang J, Schultz PG, Johnson KA. Proc Natl Acad Sci U S A. 2018 May 15;115(20):E4604-E4612. doi: 10.1073/pnas.1800260115. Epub 2018 Apr 30. PubMed |
| Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes. Wang J, Hammond J, Johnson KA. J Vis Exp. 2019 Jan 30;(143). doi: 10.3791/59021. PubMed |
| Short antisense oligonucleotides alleviate the pleiotropic toxicity of RNA harboring expanded CGG repeats. Derbis M, Kul E, Niewiadomska D, Sekrecki M, Piasecka A, Taylor K, Hukema RK, Stork O, Sobczak K. Nat Commun. 2021 Feb 24;12(1):1265. doi: 10.1038/s41467-021-21021-w. PubMed |
| Recognition of single-stranded nucleic acids by small-molecule splicing modulators. Tang Z, Akhter S, Ramprasad A, Wang X, Reibarkh M, Wang J, Aryal S, Thota SS, Zhao J, Douglas JT, Gao P, Holmstrom ED, Miao Y, Wang J. Nucleic Acids Res. 2021 Aug 20;49(14):7870-7883. doi: 10.1093/nar/gkab602. PubMed |
CRISPR-Mediated Enzyme Fragment Complementation Assay for Quantification of the Stability of Splice Isoforms.
Tang Z, Hegde S, Zhao J, Zhu S, Johnson KA, Lorson CL, Wang J.
Chembiochem. 2022 May 4;23(9):e202200012. doi: 10.1002/cbic.202200012. Epub 2022 Mar 14.
PubMed
Associated Plasmids |
| Simultaneous multifunctional transcriptome engineering by CRISPR RNA scaffold. Liu Z, Jillette N, Robson P, Cheng AW. Nucleic Acids Res. 2023 Aug 11;51(14):e77. doi: 10.1093/nar/gkad547. PubMed |
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