pdCas9-DNMT3A-EGFP (ANV) Citations (7)
Originally described in: Repurposing the CRISPR-Cas9 system for targeted DNA methylation.Vojta A, Dobrinic P, Tadic V, Bockor L, Korac P, Julg B, Klasic M, Zoldos V Nucleic Acids Res. 2016 Mar 11. pii: gkw159. PubMed Journal
Articles Citing pdCas9-DNMT3A-EGFP (ANV)
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Targeted DNA methylation in human cells using engineered dCas9-methyltransferases.
Xiong T, Meister GE, Workman RE, Kato NC, Spellberg MJ, Turker F, Timp W, Ostermeier M, Novina CD.
Sci Rep. 2017 Jul 27;7(1):6732. doi: 10.1038/s41598-017-06757-0.
PubMed
Associated Plasmids |
| Genome-wide tracking of dCas9-methyltransferase footprints. Galonska C, Charlton J, Mattei AL, Donaghey J, Clement K, Gu H, Mohammad AW, Stamenova EK, Cacchiarelli D, Klages S, Timmermann B, Cantz T, Scholer HR, Gnirke A, Ziller MJ, Meissner A. Nat Commun. 2018 Feb 9;9(1):597. doi: 10.1038/s41467-017-02708-5. PubMed |
| Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis. Qian P, De Kumar B, He XC, Nolte C, Gogol M, Ahn Y, Chen S, Li Z, Xu H, Perry JM, Hu D, Tao F, Zhao M, Han Y, Hall K, Peak A, Paulson A, Zhao C, Venkatraman A, Box A, Perera A, Haug JS, Parmely T, Li H, Krumlauf R, Li L. Cell Stem Cell. 2018 May 3;22(5):740-754.e7. doi: 10.1016/j.stem.2018.04.012. PubMed |
| Regulation of MYB by distal enhancer elements in human myeloid leukemia. Li M, Jiang P, Cheng K, Zhang Z, Lan S, Li X, Zhao L, Wang Y, Wang X, Chen J, Ji T, Han B, Zhang J. Cell Death Dis. 2021 Feb 26;12(2):223. doi: 10.1038/s41419-021-03515-z. PubMed |
| Bi-directional gene activation and repression promote ASC differentiation and enhance bone healing in osteoporotic rats. Truong VA, Lin YH, Nguyen NTK, Hsu MN, Pham NN, Chang YH, Chang CW, Shen CC, Lee HS, Lai PL, Parfyonova YV, Menshikov M, Wu JC, Chang YH, Hu YC. Mol Ther. 2022 Jan 5;30(1):92-104. doi: 10.1016/j.ymthe.2021.08.024. Epub 2021 Aug 25. PubMed |
| Genome-wide DNA hypermethylation opposes healing in patients with chronic wounds by impairing epithelial-mesenchymal transition. Singh K, Rustagi Y, Abouhashem AS, Tabasum S, Verma P, Hernandez E, Pal D, Khona DK, Mohanty SK, Kumar M, Srivastava R, Guda PR, Verma SS, Mahajan S, Killian JA, Walker LA, Ghatak S, Mathew-Steiner SS, Wanczyk KE, Liu S, Wan J, Yan P, Bundschuh R, Khanna S, Gordillo GM, Murphy MP, Roy S, Sen CK. J Clin Invest. 2022 Sep 1;132(17):e157279. doi: 10.1172/JCI157279. PubMed |
| Independent osteoarthritis risk-conferring alleles mediate the same epigenetic and transcriptional effect on a shared target gene, COLGALT2. Kehayova YS, Wilkinson JM, Rice SJ, Loughlin J. Arthritis Rheumatol. 2022 Dec 20. doi: 10.1002/art.42427. PubMed |
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