pMIG-FLAG-MLL-AF9 Citations (16)

Originally described in: AMPK Protects Leukemia-Initiating Cells in Myeloid Leukemias from Metabolic Stress in the Bone Marrow.
Saito Y, Chapple RH, Lin A, Kitano A, Nakada D Cell Stem Cell. 2015 Sep 29. pii: S1934-5909(15)00374-4. doi: 10.1016/j.stem.2015.08.019. PubMed Journal

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Articles Citing pMIG-FLAG-MLL-AF9

Articles
Murine Retrovirally-Transduced Bone Marrow Engraftment Models of MLL-Fusion-Driven Acute Myelogenous Leukemias (AML). Stubbs MC, Krivtsov AV. Curr Protoc Pharmacol. 2017 Sep 11;78:14.42.1-14.42.19. doi: 10.1002/cpph.28. PubMed
Honokiol is a FOXM1 antagonist. Halasi M, Hitchinson B, Shah BN, Varaljai R, Khan I, Benevolenskaya EV, Gaponenko V, Arbiser JL, Gartel AL. Cell Death Dis. 2018 Jan 24;9(2):84. doi: 10.1038/s41419-017-0156-7. PubMed
CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis. Greenblatt SM, Man N, Hamard PJ, Asai T, Karl D, Martinez C, Bilbao D, Stathias V, Jermakowicz AM, Duffort S, Tadi M, Blumenthal E, Newman S, Vu L, Xu Y, Liu F, Schurer SC, McCabe MT, Kruger RG, Xu M, Yang FC, Tenen DG, Watts J, Vega F, Nimer SD. Cancer Cell. 2018 Jun 11;33(6):1111-1127.e5. doi: 10.1016/j.ccell.2018.05.007. PubMed
EVI1 triggers metabolic reprogramming associated with leukemogenesis and increases sensitivity to L-asparaginase. Saito Y, Sawa D, Kinoshita M, Yamada A, Kamimura S, Suekane A, Ogoh H, Matsuo H, Adachi S, Taga T, Tomizawa D, Osato M, Soga T, Morishita K, Moritake H. Haematologica. 2020 Aug;105(8):2118-2129. doi: 10.3324/haematol.2019.225953. Epub 2019 Oct 24. PubMed
Integrated transcriptomic and epigenetic data analysis identifiesaberrant expression of genes in acute myeloid leukemia with MLLAF9 translocation. Wang F, Li Z, Wang G, Tian X, Zhou J, Yu W, Fan Z, Dong L, Lu J, Xu J, Zhang W, Liang A. Mol Med Rep. 2020 Feb;21(2):883-893. doi: 10.3892/mmr.2019.10849. Epub 2019 Nov 26. PubMed
Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia. Gu Z, Liu Y, Zhang Y, Cao H, Lyu J, Wang X, Wylie A, Newkirk SJ, Jones AE, Lee M Jr, Botten GA, Deng M, Dickerson KE, Zhang CC, An W, Abrams JM, Xu J. Nat Genet. 2021 May;53(5):672-682. doi: 10.1038/s41588-021-00829-8. Epub 2021 Apr 8. PubMed
Nuclear NAD(+) homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells. Shi X, Jiang Y, Kitano A, Hu T, Murdaugh RL, Li Y, Hoegenauer KA, Chen R, Takahashi K, Nakada D. Sci Adv. 2021 Jul 21;7(30). pii: 7/30/eabf3895. doi: 10.1126/sciadv.abf3895. Print 2021 Jul. PubMed
Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications. Lopes M, Duarte TL, Teles MJ, Mosteo L, Chacim S, Aguiar E, Pereira-Reis J, Oliveira M, Silva AMN, Goncalves N, Martins G, Kong IY, Zethoven M, Vervoort S, Martins S, Quintela M, Hawkins ED, Trigo F, Guimaraes JT, Mariz JM, Porto G, Duarte D. Blood Adv. 2021 Aug 24;5(16):3102-3112. doi: 10.1182/bloodadvances.2021004373. PubMed
Mannose and phosphomannose isomerase regulate energy metabolism under glucose starvation in leukemia. Saito Y, Kinoshita M, Yamada A, Kawano S, Liu HS, Kamimura S, Nakagawa M, Nagasawa S, Taguchi T, Yamada S, Moritake H. Cancer Sci. 2021 Dec;112(12):4944-4956. doi: 10.1111/cas.15138. Epub 2021 Oct 12. PubMed
Histone H3K36me2-Specific Methyltransferase ASH1L Promotes MLL-AF9-Induced Leukemogenesis. Aljazi MB, Gao Y, Wu Y, Mias GI, He J. Front Oncol. 2021 Oct 8;11:754093. doi: 10.3389/fonc.2021.754093. eCollection 2021. PubMed
High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in MLL/AF9 Acute Myeloid Leukemia. Liu L, Patnana PK, Xie X, Frank D, Nimmagadda SC, Rosemann A, Liebmann M, Klotz L, Opalka B, Khandanpour C. Cancers (Basel). 2022 Jan 19;14(3). pii: cancers14030486. doi: 10.3390/cancers14030486. PubMed
Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia. Brabson JP, Leesang T, Yap YS, Wang J, Lam MQ, Fang B, Dolgalev I, Barbieri DA, Strippoli V, Banuelos CP, Mohammad S, Lyon P, Chaudhry S, Donich D, Swirski A, Roberts E, Diaz I, Karl D, Dos Santos HG, Shiekhattar R, Neel BG, Nimer SD, Verdun RE, Bilbao D, Figueroa ME, Cimmino L. Cell Rep. 2023 Jan 31;42(1):112027. doi: 10.1016/j.celrep.2023.112027. Epub 2023 Jan 23. PubMed
ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m(6)A modification-mediated RNA stability control. Gao Y, Zimmer JT, Vasic R, Liu C, Gbyli R, Zheng SJ, Patel A, Liu W, Qi Z, Li Y, Nelakanti R, Song Y, Biancon G, Xiao AZ, Slavoff S, Kibbey RG, Flavell RA, Simon MD, Tebaldi T, Li HB, Halene S. Cell Rep. 2023 Oct 31;42(10):113163. doi: 10.1016/j.celrep.2023.113163. Epub 2023 Sep 23. PubMed
The DNA damage-independent ATM signalling maintains CBP/DOT1L axis in MLL rearranged acute myeloid leukaemia. Wang G, Zhang W, Ren J, Zeng Y, Dang X, Tian X, Yu W, Li Z, Ma Y, Yang P, Lu J, Zheng J, Lu B, Xu J, Liang A. Oncogene. 2024 Jun;43(25):1900-1916. doi: 10.1038/s41388-024-02998-2. Epub 2024 Apr 26. PubMed
SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis. Yu PC, Hou D, Chang B, Liu N, Xu CH, Chen X, Hu CL, Liu T, Wang X, Zhang Q, Liu P, Jiang Y, Fei MY, Zong LJ, Zhang JY, Liu H, Chen BY, Chen SB, Wang Y, Li ZJ, Li X, Deng CH, Ren YY, Zhao M, Jiang S, Wang R, Jin J, Yang S, Xue K, Shi J, Chang CK, Shen S, Wang Z, He PC, Chen Z, Chen SJ, Sun XJ, Wang L. Dev Cell. 2024 May 17:S1534-5807(24)00296-X. doi: 10.1016/j.devcel.2024.04.023. PubMed
Myeloid Targeted Human MLL-ENL and MLL-AF9 Induces cdk9 and bcl2 Expression in Zebrafish Embryos. Belt AJ, Grant S, Tombes RM, Rothschild SC. PLoS Genet. 2024 Jun 3;20(6):e1011308. doi: 10.1371/journal.pgen.1011308. eCollection 2024 Jun. PubMed

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