pLVX-EF1alpha-2xGFP:NES-IRES-2xRFP:NLS Citations (8)

Originally described in: Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.
Mertens J, Paquola AC, Ku M, Hatch E, Bohnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Goncalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH Cell Stem Cell. 2015 Oct 6. pii: S1934-5909(15)00408-7. doi: 10.1016/j.stem.2015.09.001. PubMed Journal

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Articles Citing pLVX-EF1alpha-2xGFP:NES-IRES-2xRFP:NLS

Articles
Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia. Paonessa F, Evans LD, Solanki R, Larrieu D, Wray S, Hardy J, Jackson SP, Livesey FJ. Cell Rep. 2019 Jan 15;26(3):582-593.e5. doi: 10.1016/j.celrep.2018.12.085. PubMed
Protocol to image and quantify nucleocytoplasmic transport in cultured cells using fluorescent in situ hybridization and a dual reporter system. Cui H, Sepehrimanesh M, Coutee CA, Akter M, Hosain MA, Ding B. STAR Protoc. 2022 Nov 3;3(4):101813. doi: 10.1016/j.xpro.2022.101813. eCollection 2022 Dec 16. PubMed
Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin beta-1 granules. McGoldrick P, Lau A, You Z, Durcan TM, Robertson J. Cell Rep. 2023 Mar 28;42(3):112134. doi: 10.1016/j.celrep.2023.112134. Epub 2023 Feb 22. PubMed
Chemically induced reprogramming to reverse cellular aging. Yang JH, Petty CA, Dixon-McDougall T, Lopez MV, Tyshkovskiy A, Maybury-Lewis S, Tian X, Ibrahim N, Chen Z, Griffin PT, Arnold M, Li J, Martinez OA, Behn A, Rogers-Hammond R, Angeli S, Gladyshev VN, Sinclair DA. Aging (Albany NY). 2023 Jul 12;15(13):5966-5989. doi: 10.18632/aging.204896. Epub 2023 Jul 12. PubMed
Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination. Li L, Li D, Sun D, Zhang X, Lei W, Wu M, Huang Q, Nian X, Dai W, Lu X, Zhou Z, Zhu Y, Xiao Y, Zhang L, Mo W, Liu Z, Zhang L. Dev Cell. 2023 Nov 6;58(21):2275-2291.e6. doi: 10.1016/j.devcel.2023.09.002. Epub 2023 Oct 20. PubMed
KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury. Lai JD, Berlind JE, Fricklas G, Lie C, Urenda JP, Lam K, Sta Maria N, Jacobs R, Yu V, Zhao Z, Ichida JK. Cell Stem Cell. 2024 Apr 4;31(4):519-536.e8. doi: 10.1016/j.stem.2024.03.004. PubMed
Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-RanGAP1, the E2 Ubc9, Crm1 and the Ran GTPase. Baytshtok V, DiMattia MA, Lima CD. Nat Commun. 2025 Jul 11;16(1):6403. doi: 10.1038/s41467-025-61694-1. PubMed
The leader proteins of Theiler's virus and Boone cardiovirus use a combination of short linear motifs (SLiMs) to target RSK kinases to the nuclear pore complex. Lizcano-Perret B, Wavreil F, Veinstein M, Duflos C, Milcamps R, Sorgeloos F, Michiels T. J Virol. 2025 Oct 23;99(10):e0127525. doi: 10.1128/jvi.01275-25. Epub 2025 Sep 10. PubMed

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