pKLV2-U6gRNA5(gGFP)-PGKBFP2AGFP-W Citations (15)

Originally described in: A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M, Ohnishi S, Cooper J, Patel M, McKerrell T, Chen B, Domingues AF, Gallipoli P, Teichmann S, Ponstingl H, McDermott U, Saez-Rodriguez J, Huntly BJ, Iorio F, Pina C, Vassiliou GS, Yusa K Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079. PubMed Journal

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Articles Citing pKLV2-U6gRNA5(gGFP)-PGKBFP2AGFP-W

Articles
Genome-scale identification of cellular pathways required for cell surface recognition. Sharma S, Bartholdson SJ, Couch ACM, Yusa K, Wright GJ. Genome Res. 2018 Sep;28(9):1372-1382. doi: 10.1101/gr.231183.117. Epub 2018 Jun 18. PubMed
CRISPR Screening in Single Cells. Henriksson J. Methods Mol Biol. 2019;1979:395-406. doi: 10.1007/978-1-4939-9240-9_23. PubMed
Establishment of a system for screening autophagic flux regulators using a modified fluorescent reporter and CRISPR/Cas9. Yazawa R, Nishida Y, Aoyama S, Tanida I, Miyatsuka T, Suzuki L, Himuro M, Haruna H, Takubo N, Shimizu T, Watada H. Biochem Biophys Res Commun. 2019 Aug 27;516(3):686-692. doi: 10.1016/j.bbrc.2019.06.129. Epub 2019 Jun 26. PubMed
Generation of Monoclonal iPSC Lines with Stable Cas9 Expression and High Cas9 Activity. Liao JQ, Zhou G, Zhou Y. Methods Mol Biol. 2020 Jun 22. doi: 10.1007/7651_2020_304. PubMed
Cell Surface Receptor Identification Using Genome-Scale CRISPR/Cas9 Genetic Screens. Sharma S, Wright GJ. J Vis Exp. 2020 Jun 6;(160). doi: 10.3791/60803. PubMed
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD. Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, Schneider-Luftman D, Herbert E, Stamp G, Brough R, Pettitt S, Lord CJ, West SC, Ahel I, Ahel D, Chapman JR, Deindl S, Boulton SJ. Mol Cell. 2021 Feb 18;81(4):767-783.e11. doi: 10.1016/j.molcel.2020.12.006. Epub 2020 Dec 16. PubMed
Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia. Thomas LW, Esposito C, Morgan RE, Price S, Young J, Williams SP, Maddalena LA, McDermott U, Ashcroft M. Commun Biol. 2021 May 21;4(1):615. doi: 10.1038/s42003-021-02098-x. PubMed
Nuclear NAD(+) homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells. Shi X, Jiang Y, Kitano A, Hu T, Murdaugh RL, Li Y, Hoegenauer KA, Chen R, Takahashi K, Nakada D. Sci Adv. 2021 Jul 21;7(30). pii: 7/30/eabf3895. doi: 10.1126/sciadv.abf3895. Print 2021 Jul. PubMed
A loss-of-adhesion CRISPR-Cas9 screening platform to identify cell adhesion-regulatory proteins and signaling pathways. de Rooij MFM, Thus YJ, Swier N, Beijersbergen RL, Pals ST, Spaargaren M. Nat Commun. 2022 Apr 19;13(1):2136. doi: 10.1038/s41467-022-29835-y. PubMed
Optimized Guide RNA Selection Improves Streptococcus pyogenes Cas9 Gene Editing of Human Hematopoietic Stem and Progenitor Cells. Verhagen HJMP, Kuijk C, Rutgers L, Kokke AM, van der Meulen SA, van Mierlo G, Voermans C, van den Akker E. CRISPR J. 2022 Oct;5(5):702-716. doi: 10.1089/crispr.2021.0112. Epub 2022 Sep 28. PubMed
Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation. Thus YJ, De Rooij MFM, Swier N, Beijersbergen RL, Guikema JEJ, Kersten MJ, Eldering E, Pals ST, Kater AP, Spaargaren M. Haematologica. 2023 Mar 1;108(3):797-810. doi: 10.3324/haematol.2022.281668. PubMed
HIRA loss transforms FH-deficient cells. Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, Harle V, Offord V, Wong K, Mora A, Speed A, Caraffini V, Tran MGB, Maher ER, Stewart GD, Vanharanta S, Adams DJ, Frezza C. Sci Adv. 2022 Oct 21;8(42):eabq8297. doi: 10.1126/sciadv.abq8297. Epub 2022 Oct 21. PubMed
SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells. Zhang L, Hsu JI, Braekeleer ED, Chen CW, Patel TD, Martell AG, Guzman AG, Wohlan K, Waldvogel SM, Urya H, Tovy A, Callen E, Murdaugh R, Richard R, Jansen S, Vissers L, de Vries BBA, Nussenzweig A, Huang S, Coarfa C, Anastas JN, Takahashi K, Vassiliou G, Goodell MA. bioRxiv [Preprint]. 2024 Jan 17:2023.08.31.555634. doi: 10.1101/2023.08.31.555634. PubMed
Genetic determinants of micronucleus formation in vivo. Adams DJ, Barlas B, McIntyre RE, Salguero I, van der Weyden L, Barros A, Vicente JR, Karimpour N, Haider A, Ranzani M, Turner G, Thompson NA, Harle V, Olvera-Leon R, Robles-Espinoza CD, Speak AO, Geisler N, Weninger WJ, Geyer SH, Hewinson J, Karp NA, Fu B, Yang F, Kozik Z, Choudhary J, Yu L, van Ruiten MS, Rowland BD, Lelliott CJ, Del Castillo Velasco-Herrera M, Verstraten R, Bruckner L, Henssen AG, Rooimans MA, de Lange J, Mohun TJ, Arends MJ, Kentistou KA, Coelho PA, Zhao Y, Zecchini H, Perry JRB, Jackson SP, Balmus G. Nature. 2024 Mar;627(8002):130-136. doi: 10.1038/s41586-023-07009-0. Epub 2024 Feb 14. PubMed
Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer. Pfeifer M, Brammeld JS, Price S, Pilling J, Bhavsar D, Farcas A, Bateson J, Sundarrajan A, Miragaia RJ, Guan N, Arnold S, Tariq L, Grondine M, Talbot S, Guerriero ML, O'Neill DJ, Young J, Company C, Dunn S, Thorpe H, Martin MJ, Maratea K, Barrell D, Ahdesmaki M, Mettetal JT, Brownell J, McDermott U. Commun Biol. 2024 Apr 24;7(1):497. doi: 10.1038/s42003-024-06190-w. PubMed

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