rtTA-N144 Citations (18)

Originally described in: MicroRNA-based conversion of human fibroblasts into striatal medium spiny neurons.
Richner M, Victor MB, Liu Y, Abernathy D, Yoo AS Nat Protoc. 2015 Oct;10(10):1543-55. doi: 10.1038/nprot.2015.102. Epub 2015 Sep 17. PubMed Journal

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Articles Citing rtTA-N144

Articles
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery. Gaj T, Staahl BT, Rodrigues GM, Limsirichai P, Ekman FK, Doudna JA, Schaffer DV. Nucleic Acids Res. 2017 Mar 2. doi: 10.1093/nar/gkx154. PubMed
MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts. Abernathy DG, Kim WK, McCoy MJ, Lake AM, Ouwenga R, Lee SW, Xing X, Li D, Lee HJ, Heuckeroth RO, Dougherty JD, Wang T, Yoo AS. Cell Stem Cell. 2017 Sep 7;21(3):332-348.e9. doi: 10.1016/j.stem.2017.08.002. PubMed
Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C, Huh CJ, Zhang B, Davidson BL, Yang XW, Yoo AS. Nat Neurosci. 2018 Mar;21(3):341-352. doi: 10.1038/s41593-018-0075-7. Epub 2018 Feb 5. PubMed
MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts. Lee SW, Oh YM, Lu YL, Kim WK, Yoo AS. Dev Cell. 2018 Jul 2;46(1):73-84.e7. doi: 10.1016/j.devcel.2018.06.007. PubMed
A versatile lentiviral delivery toolkit for proximity-dependent biotinylation in diverse cell types. Samavarchi-Tehrani P, Abdouni H, Samson R, Gingras AC. Mol Cell Proteomics. 2018 Jul 10. pii: TIR118.000902. doi: 10.1074/mcp.TIR118.000902. PubMed
De Novo PITX1 Expression Controls Bi-Stable Transcriptional Circuits to Govern Self-Renewal and Differentiation in Squamous Cell Carcinoma. Sastre-Perona A, Hoang-Phou S, Leitner MC, Okuniewska M, Meehan S, Schober M. Cell Stem Cell. 2019 Mar 7;24(3):390-404.e8. doi: 10.1016/j.stem.2019.01.003. Epub 2019 Jan 31. PubMed
Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP. Kim B, Arcos S, Rothamel K, Jian J, Rose KL, McDonald WH, Bian Y, Reasoner S, Barrows NJ, Bradrick S, Garcia-Blanco MA, Ascano M. Mol Cell. 2020 May 21;78(4):624-640.e7. doi: 10.1016/j.molcel.2020.04.013. Epub 2020 May 6. PubMed
High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down. Li X, Pritykin Y, Concepcion CP, Lu Y, La Rocca G, Zhang M, King B, Cook PJ, Au YW, Popow O, Paulo JA, Otis HG, Mastroleo C, Ogrodowski P, Schreiner R, Haigis KM, Betel D, Leslie CS, Ventura A. Mol Cell. 2020 Jul 2;79(1):167-179.e11. doi: 10.1016/j.molcel.2020.05.009. Epub 2020 Jun 3. PubMed
Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production. Chen H, Victor AK, Klein J, Tacer KF, Tai DJ, de Esch C, Nuttle A, Temirov J, Burnett LC, Rosenbaum M, Zhang Y, Ding L, Moresco JJ, Diedrich JK, Yates JR 3rd, Tillman HS, Leibel RL, Talkowski ME, Billadeau DD, Reiter LT, Potts PR. JCI Insight. 2020 Sep 3;5(17). pii: 138576. doi: 10.1172/jci.insight.138576. PubMed
Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs. Cates K, McCoy MJ, Kwon JS, Liu Y, Abernathy DG, Zhang B, Liu S, Gontarz P, Kim WK, Chen S, Kong W, Ho JN, Burbach KF, Gabel HW, Morris SA, Yoo AS. Cell Stem Cell. 2021 Jan 7;28(1):127-140.e9. doi: 10.1016/j.stem.2020.08.015. Epub 2020 Sep 21. PubMed
Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A. Franco A, Dang X, Walton EK, Ho JN, Zablocka B, Ly C, Miller TM, Baloh RH, Shy ME, Yoo AS, Dorn GW 2nd. Elife. 2020 Oct 19;9. pii: 61119. doi: 10.7554/eLife.61119. PubMed
Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells. Dermit M, Dodel M, Lee FCY, Azman MS, Schwenzer H, Jones JL, Blagden SP, Ule J, Mardakheh FK. Dev Cell. 2020 Nov 9;55(3):298-313.e10. doi: 10.1016/j.devcel.2020.10.006. PubMed
Generation of Human Neurons by microRNA-Mediated Direct Conversion of Dermal Fibroblasts. Church VA, Cates K, Capano L, Aryal S, Kim WK, Yoo AS. Methods Mol Biol. 2021;2239:77-100. doi: 10.1007/978-1-0716-1084-8_6. PubMed
A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics. Steenkiste EM, Berndt JD, Pilling C, Simpkins C, Cooper JA. Elife. 2021 Jun 25;10. pii: 67078. doi: 10.7554/eLife.67078. PubMed
IPSC-Derived Human Neurons with GCaMP6s Expression Allow In Vitro Study of Neurophysiological Responses to Neurochemicals. Galiakberova AA, Surin AM, Bakaeva ZV, Sharipov RR, Zhang D, Dorovskoy DA, Shakirova KM, Fisenko AP, Dashinimaev EB. Neurochem Res. 2022 Apr;47(4):952-966. doi: 10.1007/s11064-021-03497-6. Epub 2021 Dec 2. PubMed
Nuclease-dead S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in patient-derived stem cell model of Parkinson's disease. Sastre D, Zafar F, Torres CAM, Piper D, Kirik D, Sanders LH, Qi S, Schule B. bioRxiv. 2023 Jan 24:2023.01.24.525105. doi: 10.1101/2023.01.24.525105. Preprint. PubMed
Protocol Optimization for Direct Reprogramming of Primary Human Fibroblast into Induced Striatal Neurons. Kraskovskaya N, Bolshakova A, Khotin M, Bezprozvanny I, Mikhailova N. Int J Mol Sci. 2023 Apr 5;24(7):6799. doi: 10.3390/ijms24076799. PubMed
Longitudinal modeling of human neuronal aging identifies RCAN1-TFEB pathway contributing to neurodegeneration of Huntington's disease. Yoo A, Lee SW, Oh YM, Victor M, Strunilin I, Chen S, Dahiya S, Dolle R, Pak S, Silverman G, Perlmutter D. Res Sq. 2023 May 9:rs.3.rs-2815300. doi: 10.21203/rs.3.rs-2815300/v1. Preprint. PubMed

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