pZT-C13-L1 Citations (15)
Originally described in: Transcription activator-like effector nuclease (TALEN)-mediated CLYBL targeting enables enhanced transgene expression and one-step generation of dual reporter human induced pluripotent stem cell (iPSC) and neural stem cell (NSC) lines.Cerbini T, Funahashi R, Luo Y, Liu C, Park K, Rao M, Malik N, Zou J PLoS One. 2015 Jan 14;10(1):e0116032. doi: 10.1371/journal.pone.0116032. eCollection 2015. PubMed Journal
Articles Citing pZT-C13-L1
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Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons.
Fernandopulle MS, Prestil R, Grunseich C, Wang C, Gan L, Ward ME.
Curr Protoc Cell Biol. 2018 Jun;79(1):e51. doi: 10.1002/cpcb.51. Epub 2018 May 18.
PubMed
Associated Plasmids |
| CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10. Huang X, Wu BP, Nguyen D, Liu YT, Marani M, Hench J, Benit P, Kozjak-Pavlovic V, Rustin P, Frank S, Narendra DP. Hum Mol Genet. 2018 Nov 15;27(22):3881-3900. doi: 10.1093/hmg/ddy270. PubMed |
CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons.
Tian R, Gachechiladze MA, Ludwig CH, Laurie MT, Hong JY, Nathaniel D, Prabhu AV, Fernandopulle MS, Patel R, Abshari M, Ward ME, Kampmann M.
Neuron. 2019 Aug 5. pii: S0896-6273(19)30640-3. doi: 10.1016/j.neuron.2019.07.014.
PubMed
Associated Plasmids |
| Generation of human endothelium in pig embryos deficient in ETV2. Das S, Koyano-Nakagawa N, Gafni O, Maeng G, Singh BN, Rasmussen T, Pan X, Choi KD, Mickelson D, Gong W, Pota P, Weaver CV, Kren S, Hanna JH, Yannopoulos D, Garry MG, Garry DJ. Nat Biotechnol. 2020 Mar;38(3):297-302. doi: 10.1038/s41587-019-0373-y. Epub 2020 Feb 24. PubMed |
Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.
Guo X, Aviles G, Liu Y, Tian R, Unger BA, Lin YT, Wiita AP, Xu K, Correia MA, Kampmann M.
Nature. 2020 Mar;579(7799):427-432. doi: 10.1038/s41586-020-2078-2. Epub 2020 Mar 4.
PubMed
Associated Plasmids |
| Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes. Kanfer G, Sarraf SA, Maman Y, Baldwin H, Dominguez-Martin E, Johnson KR, Ward ME, Kampmann M, Lippincott-Schwartz J, Youle RJ. J Cell Biol. 2021 Feb 1;220(2). pii: 211694. doi: 10.1083/jcb.202006180. PubMed |
| Bioengineered optogenetic model of human neuromuscular junction. Vila OF, Chavez M, Ma SP, Yeager K, Zholudeva LV, Colon-Mercado JM, Qu Y, Nash TR, Lai C, Feliciano CM, Carter M, Kamm RD, Judge LM, Conklin BR, Ward ME, McDevitt TC, Vunjak-Novakovic G. Biomaterials. 2021 Sep;276:121033. doi: 10.1016/j.biomaterials.2021.121033. Epub 2021 Jul 30. PubMed |
| Allele-Specific Gene Editing Rescues Pathology in a Human Model of Charcot-Marie-Tooth Disease Type 2E. Feliciano CM, Wu K, Watry HL, Marley CBE, Ramadoss GN, Ghanim HY, Liu AZ, Zholudeva LV, McDevitt TC, Saporta MA, Conklin BR, Judge LM. Front Cell Dev Biol. 2021 Aug 16;9:723023. doi: 10.3389/fcell.2021.723023. eCollection 2021. PubMed |
| Assessing Gq-GPCR-induced human astrocyte reactivity using bioengineered neural organoids. Cvetkovic C, Patel R, Shetty A, Hogan MK, Anderson M, Basu N, Aghlara-Fotovat S, Ramesh S, Sardar D, Veiseh O, Ward ME, Deneen B, Horner PJ, Krencik R. J Cell Biol. 2022 Feb 9;221(4):e202107135. doi: 10.1083/jcb.202107135. Epub 2022 Feb 9. PubMed |
| Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons. Chua JP, Bedi K, Paulsen MT, Ljungman M, Tank EMH, Kim ES, McBride JP, Colon-Mercado JM, Ward ME, Weisman LS, Barmada SJ. Curr Biol. 2022 Jun 20;32(12):2581-2595.e6. doi: 10.1016/j.cub.2022.04.053. Epub 2022 May 16. PubMed |
| CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis. Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Parra Bravo C, Goodness D, Tian R, Grosjean P, Abskharon R, Eisenberg D, Kanaan NM, Gan L, Condello C, Swaney DL, Kampmann M. bioRxiv. 2023 Jun 26:2023.06.16.545386. doi: 10.1101/2023.06.16.545386. Preprint. PubMed |
| Regulation potential of transcribed simple repeated sequences in developing neurons. Chung TH, Zhuravskaya A, Makeyev EV. Hum Genet. 2023 Dec 28. doi: 10.1007/s00439-023-02626-1. PubMed |
| Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening. Li X, Sun S, Zhang W, Liang Z, Fang Y, Sun T, Wan Y, Ma X, Zhang S, Xu Y, Tian R. J Exp Clin Cancer Res. 2024 Apr 1;43(1):95. doi: 10.1186/s13046-024-03027-6. PubMed |
| Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded beta-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease. Williams D, Glasstetter LM, Jong TT, Kapoor A, Zhu S, Zhu Y, Gehrlein A, Vocadlo DJ, Jagasia R, Marugan JJ, Sidransky E, Henderson MJ, Chen Y. bioRxiv [Preprint]. 2024 Mar 27:2024.03.22.586364. doi: 10.1101/2024.03.22.586364. PubMed |
| Therapeutic validation of MMR-associated genetic modifiers in a human ex vivo model of Huntington disease. Ferguson R, Goold R, Coupland L, Flower M, Tabrizi SJ. Am J Hum Genet. 2024 Jun 6;111(6):1165-1183. doi: 10.1016/j.ajhg.2024.04.015. Epub 2024 May 14. PubMed |
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