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pX603-AAV-CMV::NLS-dSaCas9(D10A,N580A)-NLS-3xHA-bGHpA Citations (13)

Originally described in: In vivo genome editing using Staphylococcus aureus Cas9.
Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F Nature. 2015 Apr 1. doi: 10.1038/nature14299. PubMed Journal

Articles Citing pX603-AAV-CMV::NLS-dSaCas9(D10A,N580A)-NLS-3xHA-bGHpA

Articles
Complex transcriptional modulation with orthogonal and inducible dCas9 regulators. Gao Y, Xiong X, Wong S, Charles EJ, Lim WA, Qi LS. Nat Methods. 2016 Oct 24. doi: 10.1038/nmeth.4042. PubMed

Associated Plasmids
ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Abeta Secretion. Huang YA, Zhou B, Wernig M, Sudhof TC. Cell. 2017 Jan 26;168(3):427-441.e21. doi: 10.1016/j.cell.2016.12.044. Epub 2017 Jan 19. PubMed
Drug-tunable multidimensional synthetic gene control using inducible degron-tagged dCas9 effectors. Kleinjan DA, Wardrope C, Nga Sou S, Rosser SJ. Nat Commun. 2017 Oct 30;8(1):1191. doi: 10.1038/s41467-017-01222-y. PubMed
Multimode drug inducible CRISPR/Cas9 devices for transcriptional activation and genome editing. Lu J, Zhao C, Zhao Y, Zhang J, Zhang Y, Chen L, Han Q, Ying Y, Peng S, Ai R, Wang Y. Nucleic Acids Res. 2018 Mar 16;46(5):e25. doi: 10.1093/nar/gkx1222. PubMed

Associated Plasmids
Feasibility of a Conditional Knockout System for Chlamydia Based on CRISPR Interference. Ouellette SP. Front Cell Infect Microbiol. 2018 Feb 27;8:59. doi: 10.3389/fcimb.2018.00059. eCollection 2018. PubMed
Targeted Transgene Activation in the Brain Tissue by Systemic Delivery of Engineered AAV1 Expressing CRISPRa. Lau CH, Ho JW, Lo PK, Tin C. Mol Ther Nucleic Acids. 2019 Jun 7;16:637-649. doi: 10.1016/j.omtn.2019.04.015. Epub 2019 Apr 23. PubMed

Associated Plasmids
Active fusions of Cas9 orthologs. Josipovic G, Zoldos V, Vojta A. J Biotechnol. 2019 Aug 10;301:18-23. doi: 10.1016/j.jbiotec.2019.05.306. Epub 2019 May 31. PubMed
The ClpX and ClpP2 Orthologs of Chlamydia trachomatis Perform Discrete and Essential Functions in Organism Growth and Development. Wood NA, Blocker AM, Seleem MA, Conda-Sheridan M, Fisher DJ, Ouellette SP. mBio. 2020 Sep 1;11(5). pii: mBio.02016-20. doi: 10.1128/mBio.02016-20. PubMed
AAV-Mediated CRISPRi and RNAi Based Gene Silencing in Mouse Hippocampal Neurons. Deutsch M, Gunther A, Lerchundi R, Rose CR, Balfanz S, Baumann A. Cells. 2021 Feb 4;10(2). pii: cells10020324. doi: 10.3390/cells10020324. PubMed
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS. Cell. 2021 Apr 7. pii: S0092-8674(21)00353-6. doi: 10.1016/j.cell.2021.03.025. PubMed

Associated Plasmids
CRISPR Interference To Inducibly Repress Gene Expression in Chlamydia trachomatis. Ouellette SP, Blay EA, Hatch ND, Fisher-Marvin LA. Infect Immun. 2021 Jun 16;89(7):e0010821. doi: 10.1128/IAI.00108-21. Epub 2021 Jun 16. PubMed
A Dynamic, Ring-Forming Bactofilin Critical for Maintaining Cell Size in the Obligate Intracellular Bacterium Chlamydia trachomatis. Brockett MR, Lee J, Cox JV, Liechti GW, Ouellette SP. Infect Immun. 2021 Jul 15;89(8):e0020321. doi: 10.1128/IAI.00203-21. Epub 2021 Jul 15. PubMed
How chromosomal translocations arise to cause cancer: Gene proximity, trans-splicing, and DNA end joining. Streb P, Kowarz E, Benz T, Reis J, Marschalek R. iScience. 2023 May 19;26(6):106900. doi: 10.1016/j.isci.2023.106900. eCollection 2023 Jun 16. PubMed

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