pTight-9-124-BclxL Citations (9)
Originally described in: Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts.Victor MB, Richner M, Hermanstyne TO, Ransdell JL, Sobieski C, Deng PY, Klyachko VA, Nerbonne JM, Yoo AS Neuron. 2014 Oct 22;84(2):311-23. doi: 10.1016/j.neuron.2014.10.016. Epub 2014 Oct 22. PubMed Journal
Articles Citing pTight-9-124-BclxL
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MicroRNA-based conversion of human fibroblasts into striatal medium spiny neurons.
Richner M, Victor MB, Liu Y, Abernathy D, Yoo AS.
Nat Protoc. 2015 Oct;10(10):1543-55. doi: 10.1038/nprot.2015.102. Epub 2015 Sep 17.
PubMed
Associated Plasmids |
| Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery. Gaj T, Staahl BT, Rodrigues GM, Limsirichai P, Ekman FK, Doudna JA, Schaffer DV. Nucleic Acids Res. 2017 Mar 2. doi: 10.1093/nar/gkx154. PubMed |
| Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C, Huh CJ, Zhang B, Davidson BL, Yang XW, Yoo AS. Nat Neurosci. 2018 Mar;21(3):341-352. doi: 10.1038/s41593-018-0075-7. Epub 2018 Feb 5. PubMed |
| MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts. Lee SW, Oh YM, Lu YL, Kim WK, Yoo AS. Dev Cell. 2018 Jul 2;46(1):73-84.e7. doi: 10.1016/j.devcel.2018.06.007. PubMed |
| Generation of Human Neurons by microRNA-Mediated Direct Conversion of Dermal Fibroblasts. Church VA, Cates K, Capano L, Aryal S, Kim WK, Yoo AS. Methods Mol Biol. 2021;2239:77-100. doi: 10.1007/978-1-0716-1084-8_6. PubMed |
| Protocol Optimization for Direct Reprogramming of Primary Human Fibroblast into Induced Striatal Neurons. Kraskovskaya N, Bolshakova A, Khotin M, Bezprozvanny I, Mikhailova N. Int J Mol Sci. 2023 Apr 5;24(7):6799. doi: 10.3390/ijms24076799. PubMed |
| Longitudinal modeling of human neuronal aging identifies RCAN1-TFEB pathway contributing to neurodegeneration of Huntington's disease. Yoo A, Lee SW, Oh YM, Victor M, Strunilin I, Chen S, Dahiya S, Dolle R, Pak S, Silverman G, Perlmutter D. Res Sq. 2023 May 9:rs.3.rs-2815300. doi: 10.21203/rs.3.rs-2815300/v1. Preprint. PubMed |
| PTBP2 attenuation facilitates fibroblast to neuron conversion by promoting alternative splicing of neuronal genes. Zhu B, Fisher E, Li L, Zhong P, Yan Z, Feng J. Stem Cell Reports. 2023 Nov 14;18(11):2268-2282. doi: 10.1016/j.stemcr.2023.09.012. Epub 2023 Oct 12. PubMed |
| A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Hruska-Plochan M, Wiersma VI, Betz KM, Mallona I, Ronchi S, Maniecka Z, Hock EM, Tantardini E, Laferriere F, Sahadevan S, Hoop V, Delvendahl I, Perez-Berlanga M, Gatta B, Panatta M, van der Bourg A, Bohaciakova D, Sharma P, De Vos L, Frontzek K, Aguzzi A, Lashley T, Robinson MD, Karayannis T, Mueller M, Hierlemann A, Polymenidou M. Nature. 2024 Feb;626(8001):1073-1083. doi: 10.1038/s41586-024-07042-7. Epub 2024 Feb 14. PubMed |
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