pSynSRE-T-Luc Citations (9)
Originally described in: Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase gene through a direct interaction between sterol regulatory element binding protein and the trimeric CCAAT-binding factor/nuclear factor Y.Dooley KA, Millinder S, Osborne TF J Biol Chem. 1998 Jan 16;273(3):1349-56. PubMed
Articles Citing pSynSRE-T-Luc
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| Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism. Kim YS, Lee YM, Oh TI, Shin DH, Kim GH, Kan SY, Kang H, Kim JH, Kim BM, Yim WJ, Lim JH. Int J Mol Sci. 2018 Oct 12;19(10). pii: ijms19103127. doi: 10.3390/ijms19103127. PubMed |
| SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY. Nat Commun. 2019 Jan 10;10(1):120. doi: 10.1038/s41467-018-08015-x. PubMed |
| Ursolic Acid Suppresses Cholesterol Biosynthesis and Exerts Anti-Cancer Effects in Hepatocellular Carcinoma Cells. Kim GH, Kan SY, Kang H, Lee S, Ko HM, Kim JH, Lim JH. Int J Mol Sci. 2019 Sep 26;20(19). pii: ijms20194767. doi: 10.3390/ijms20194767. PubMed |
| Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency. Shin S, Zhou H, He C, Wei Y, Wang Y, Shingu T, Zeng A, Wang S, Zhou X, Li H, Zhang Q, Mo Q, Long J, Lan F, Chen Y, Hu J. Nat Commun. 2021 May 21;12(1):3005. doi: 10.1038/s41467-021-22782-0. PubMed |
| Low-Density Lipoprotein Receptor-Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes. Chow HM, Sun JK, Hart RP, Cheng KK, Hung CHL, Lau TM, Kwan KM. Adv Sci (Weinh). 2021 Aug;8(16):e2004993. doi: 10.1002/advs.202004993. Epub 2021 Jun 27. PubMed |
| A novel MBTPS2 variant associated with BRESHECK syndrome impairs sterol-regulated transcription and the endoplasmic reticulum stress response. Strong A, March ME, Cardinale CJ, Kim SE, Merves J, Whitworth H, Raffini L, Larosa C, Copelovitch L, Hou C, Slater D, Vaccaro C, Watson D, Zackai EH, Billheimer J, Hakonarson H. Am J Med Genet A. 2022 Feb;188(2):463-472. doi: 10.1002/ajmg.a.62537. Epub 2021 Oct 15. PubMed |
| Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection. Firpo MR, LoMascolo NJ, Petit MJ, Shah PS, Mounce BC. PLoS Pathog. 2023 Apr 18;19(4):e1011317. doi: 10.1371/journal.ppat.1011317. eCollection 2023 Apr. PubMed |
| Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition. Chin CF, Galam D, Gao L, Tan BC, Wong BH, Chua GL, Loke RY, Lim YC, Wenk MR, Lim MS, Leow WQ, Goh GB, Torta F, Silver DL. J Clin Invest. 2023 Sep 1;133(17):e171267. doi: 10.1172/JCI171267. PubMed |
| Carbon dioxide regulates cholesterol levels through SREBP2. Bolshette N, Ezagouri S, Dandavate V, Karavaeva I, Golik M, Wang H, Espenshade PJ, Osborne TF, Han X, Asher G. PLoS Biol. 2023 Nov 15;21(11):e3002367. doi: 10.1371/journal.pbio.3002367. eCollection 2023 Nov. PubMed |
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