pICE-RNaseHI-D10R-E48R-NLS-mCherry Citations (10)
Originally described in: DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal.Britton S, Dernoncourt E, Delteil C, Froment C, Schiltz O, Salles B, Frit P, Calsou P Nucleic Acids Res. 2014 Oct 1;42(14):9047-62. doi: 10.1093/nar/gku601. Epub 2014 Jul 16. PubMed Journal
Articles Citing pICE-RNaseHI-D10R-E48R-NLS-mCherry
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PRPF8 is important for BRCA1-mediated homologous recombination. Onyango DO, Lee G, Stark JM. Oncotarget. 2017 Oct 6;8(55):93319-93337. doi: 10.18632/oncotarget.21555. eCollection 2017 Nov 7. PubMed |
Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair. Lu WT, Hawley BR, Skalka GL, Baldock RA, Smith EM, Bader AS, Malewicz M, Watts FZ, Wilczynska A, Bushell M. Nat Commun. 2018 Feb 7;9(1):532. doi: 10.1038/s41467-018-02893-x. PubMed |
Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication. Klusmann I, Wohlberedt K, Magerhans A, Teloni F, Korbel JO, Altmeyer M, Dobbelstein M. Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11311-E11320. doi: 10.1073/pnas.1809592115. Epub 2018 Nov 9. PubMed |
Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach.
Yan Q, Shields EJ, Bonasio R, Sarma K.
Cell Rep. 2019 Oct 29;29(5):1369-1380.e5. doi: 10.1016/j.celrep.2019.09.052.
PubMed
Associated Plasmids |
FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops. Pan X, Chen Y, Biju B, Ahmed N, Kong J, Goldenberg M, Huang J, Mohan N, Klosek S, Parsa K, Guh CY, Lu R, Pickett HA, Chu HP, Zhang D. Sci Rep. 2019 Dec 13;9(1):19110. doi: 10.1038/s41598-019-55537-5. PubMed |
Mdm4 supports DNA replication in a p53-independent fashion. Wohlberedt K, Klusmann I, Derevyanko PK, Henningsen K, Choo JAMY, Manzini V, Magerhans A, Giansanti C, Eischen CM, Jochemsen AG, Dobbelstein M. Oncogene. 2020 Jun;39(25):4828-4843. doi: 10.1038/s41388-020-1325-1. Epub 2020 May 19. PubMed |
The integrated stress response induces R-loops and hinders replication fork progression. Choo JAMY, Schlosser D, Manzini V, Magerhans A, Dobbelstein M. Cell Death Dis. 2020 Jul 16;11(7):538. doi: 10.1038/s41419-020-2727-2. PubMed |
Aicardi-Goutieres syndrome-associated gene SAMHD1 preserves genome integrity by preventing R-loop formation at transcription-replication conflict regions. Park K, Ryoo J, Jeong H, Kim M, Lee S, Hwang SY, Ahn J, Kim D, Moon HC, Baek D, Kim K, Park HY, Ahn K. PLoS Genet. 2021 Apr 15;17(4):e1009523. doi: 10.1371/journal.pgen.1009523. eCollection 2021 Apr. PubMed |
Proximity labeling identifies a repertoire of site-specific R-loop modulators. Yan Q, Wulfridge P, Doherty J, Fernandez-Luna JL, Real PJ, Tang HY, Sarma K. Nat Commun. 2022 Jan 10;13(1):53. doi: 10.1038/s41467-021-27722-6. PubMed |
XPF activates break-induced telomere synthesis. Guh CY, Shen HJ, Chen LW, Chiu PC, Liao IH, Lo CC, Chen Y, Hsieh YH, Chang TC, Yen CP, Chen YY, Chen TW, Chen LY, Wu CS, Egly JM, Chu HC. Nat Commun. 2022 Oct 2;13(1):5781. doi: 10.1038/s41467-022-33428-0. PubMed |
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