AAV:ITR-U6-sgRNA(Kras)-U6-sgRNA(p53)-U6-sgRNA(Lkb1)-pEFS-Rluc-2A-Cre-shortPA-KrasG12D_HDRdonor-ITR (AAV-KPL) Citations (5)

Originally described in: CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling.
Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, Anderson DG, Hacohen N, Regev A, Feng G, Sharp PA, Zhang F Cell. 2014 Sep 24. pii: S0092-8674(14)01163-5. doi: 10.1016/j.cell.2014.09.014. PubMed Journal

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Articles Citing AAV:ITR-U6-sgRNA(Kras)-U6-sgRNA(p53)-U6-sgRNA(Lkb1)-pEFS-Rluc-2A-Cre-shortPA-KrasG12D_HDRdonor-ITR (AAV-KPL)

Articles
BIRC5 is a target for molecular imaging and detection of human pancreatic cancer. Liu SH, Hong Y, Markowiak S, Sanchez R, Creeden J, Nemunaitis J, Kalinoski A, Willey J, Erhardt P, Lee J, van Dam M, Brunicardi FC. Cancer Lett. 2019 Aug 10;457:10-19. doi: 10.1016/j.canlet.2019.04.036. Epub 2019 May 3. PubMed
Comparative Analysis of Stk11/Lkb1 versus Pten Deficiency in Lung Adenocarcinoma Induced by CRISPR/Cas9. Berthelsen MF, Leknes SL, Riedel M, Pedersen MA, Joseph JV, Hager H, Vendelbo MH, Thomsen MK. Cancers (Basel). 2021 Feb 26;13(5). pii: cancers13050974. doi: 10.3390/cancers13050974. PubMed
Protocol to package and concentrate adeno-associated virus serotype 8 for use in autochthonous mouse models of pancreatic cancer. Zhuo M, Mao J, David CJ. STAR Protoc. 2023 Feb 9;4(1):102108. doi: 10.1016/j.xpro.2023.102108. PubMed
Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice. Bu W, Creighton CJ, Heavener KS, Gutierrez C, Dou Y, Ku AT, Zhang Y, Jiang W, Urrutia J, Jiang W, Yue F, Jia L, Ibrahim AA, Zhang B, Huang S, Li Y. Sci Adv. 2023 May 12;9(19):eade0059. doi: 10.1126/sciadv.ade0059. Epub 2023 May 12. PubMed
Propionate reinforces epithelial identity and reduces aggressiveness of lung carcinoma. Ramesh V, Gollavilli PN, Pinna L, Siddiqui MA, Turtos AM, Napoli F, Antonelli Y, Leal-Egana A, Havelund JF, Jakobsen ST, Boiteux EL, Volante M, Faergeman NJ, Jensen ON, Siersbaek R, Somyajit K, Ceppi P. EMBO Mol Med. 2023 Dec 7;15(12):e17836. doi: 10.15252/emmm.202317836. Epub 2023 Sep 28. PubMed

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