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pOTTC414 - pAAV EF1a hPREP Citations (3)

Originally described in: The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse.
Savolainen MH, Richie CT, Harvey BK, Mannisto PT, Maguire-Zeiss KA, Myohanen TT Neurobiol Dis. 2014 Aug;68:1-15. doi: 10.1016/j.nbd.2014.04.003. Epub 2014 Apr 16.
PubMed Journal

Articles Citing pOTTC414 - pAAV EF1a hPREP

Articles
Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo. Svarcbahs R, Julku UH, Norrbacka S, Myohanen TT. Sci Rep. 2018 Jan 24;8(1):1552. doi: 10.1038/s41598-018-19823-y. PubMed
Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A. Svarcbahs R, Jantti M, Kilpelainen T, Julku UH, Urvas L, Kivioja S, Norrbacka S, Myohanen TT. Pharmacol Res. 2020 Jan;151:104558. doi: 10.1016/j.phrs.2019.104558. Epub 2019 Nov 20. PubMed
Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner. Julku UH, Jantti M, Svarcbahs R, Myohanen TT. Int J Mol Sci. 2021 Feb 10;22(4). pii: ijms22041777. doi: 10.3390/ijms22041777. PubMed

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