pX330 Pten Citations (6)

Originally described in: CRISPR-mediated direct mutation of cancer genes in the mouse liver.
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T Nature. 2014 Aug 6. doi: 10.1038/nature13589. PubMed Journal

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Articles Citing pX330 Pten

Articles
CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice. Gao M, Liu D. Cancer Biol Ther. 2017 May 17:1-8. doi: 10.1080/15384047.2017.1323597. PubMed
A Novel Rat Model of Nonalcoholic Fatty Liver Disease Constructed Through CRISPR/Cas-Based Hydrodynamic Injection. Yu Q, Tan RZ, Gan Q, Zhong X, Wang YQ, Zhou J, Wang L. Mol Biotechnol. 2017 Oct;59(9-10):365-373. doi: 10.1007/s12033-017-0025-8. PubMed
Inducing and exploiting vulnerabilities for the treatment of liver cancer. Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, de Oliveira RL, Morris B, Gadiot J, Wang W, du Chatinier A, Wang L, Gao D, Evers B, Jin G, Xue Z, Schepers A, Jochems F, Sanchez AM, Mainardi S, Te Riele H, Beijersbergen RL, Qin W, Akkari L, Bernards R. Nature. 2019 Oct;574(7777):268-272. doi: 10.1038/s41586-019-1607-3. Epub 2019 Oct 2. PubMed
The mTOR pathway genes mTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function. Nguyen LH, Xu Y, Nair M, Bordey A. bioRxiv [Preprint]. 2024 Jan 6:2023.08.11.553034. doi: 10.1101/2023.08.11.553034. PubMed
The mTOR pathway genes MTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function. Nguyen LH, Xu Y, Nair M, Bordey A. Elife. 2024 Feb 27;12:RP91010. doi: 10.7554/eLife.91010. PubMed
Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma. Ramirez CFA, Taranto D, Ando-Kuri M, de Groot MHP, Tsouri E, Huang Z, de Groot D, Kluin RJC, Kloosterman DJ, Verheij J, Xu J, Vegna S, Akkari L. Nat Commun. 2024 Mar 22;15(1):2581. doi: 10.1038/s41467-024-46835-2. PubMed

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