pL-CRISPR.EFS.tRFP Citations (26)
Originally described in: Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing.Heckl D, Kowalczyk MS, Yudovich D, Belizaire R, Puram RV, McConkey ME, Thielke A, Aster JC, Regev A, Ebert BL Nat Biotechnol. 2014 Jun 22. doi: 10.1038/nbt.2951. PubMed Journal
Articles Citing pL-CRISPR.EFS.tRFP
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Chromosome conformation elucidates regulatory relationships in developing human brain. Won H, de la Torre-Ubieta L, Stein JL, Parikshak NN, Huang J, Opland CK, Gandal MJ, Sutton GJ, Hormozdiari F, Lu D, Lee C, Eskin E, Voineagu I, Ernst J, Geschwind DH. Nature. 2016 Oct 27;538(7626):523-527. doi: 10.1038/nature19847. Epub 2016 Oct 19. PubMed |
CRMP2 is necessary for Neurofibromatosis type 1 related pain. Moutal A, Cai S, Luo S, Voisin R, Khanna R. Channels (Austin). 2018 Jan 1;12(1):47-50. doi: 10.1080/19336950.2017.1370524. PubMed |
The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis. de la Torre-Ubieta L, Stein JL, Won H, Opland CK, Liang D, Lu D, Geschwind DH. Cell. 2018 Jan 11;172(1-2):289-304.e18. doi: 10.1016/j.cell.2017.12.014. Epub 2018 Jan 4. PubMed |
TAF1-gene editing alters the morphology and function of the cerebellum and cerebral cortex. Janakiraman U, Yu J, Moutal A, Chinnasamy D, Boinon L, Batchelor SN, Anandhan A, Khanna R, Nelson MA. Neurobiol Dis. 2019 Dec;132:104539. doi: 10.1016/j.nbd.2019.104539. Epub 2019 Jul 22. PubMed |
TraFo-CRISPR: Enhanced Genome Engineering by Transient Foamy Virus Vector-Mediated Delivery of CRISPR/Cas9 Components. Lindel F, Dodt CR, Weidner N, Noll M, Bergemann F, Behrendt R, Fischer S, Dietrich J, Cartellieri M, Hamann MV, Lindemann D. Mol Ther Nucleic Acids. 2019 Dec 6;18:708-726. doi: 10.1016/j.omtn.2019.10.006. Epub 2019 Oct 17. PubMed |
A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol. Fessler E, Eckl EM, Schmitt S, Mancilla IA, Meyer-Bender MF, Hanf M, Philippou-Massier J, Krebs S, Zischka H, Jae LT. Nature. 2020 Mar;579(7799):433-437. doi: 10.1038/s41586-020-2076-4. Epub 2020 Mar 4. PubMed |
Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release. Opsomer R, Contino S, Perrin F, Gualdani R, Tasiaux B, Doyen P, Vergouts M, Vrancx C, Doshina A, Pierrot N, Octave JN, Gailly P, Stanga S, Kienlen-Campard P. eNeuro. 2020 May 28;7(3):ENEURO.0322-19.2020. doi: 10.1523/ENEURO.0322-19.2020. Print 2020 May/Jun. PubMed |
The investigation of the T-type calcium channel enhancer SAK3 in an animal model of TAF1 intellectual disability syndrome. Janakiraman U, Dhanalakshmi C, Yu J, Moutal A, Boinon L, Fukunaga K, Khanna R, Nelson MA. Neurobiol Dis. 2020 Sep;143:105006. doi: 10.1016/j.nbd.2020.105006. Epub 2020 Jul 2. PubMed |
FGFR1 Is Critical for RBL2 Loss-Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer. Kim KB, Kim Y, Rivard CJ, Kim DW, Park KS. Cancer Res. 2020 Nov 15;80(22):5051-5062. doi: 10.1158/0008-5472.CAN-20-1453. Epub 2020 Sep 24. PubMed |
MLLT6 maintains PD-L1 expression and mediates tumor immune resistance. Sreevalsan S, Doring M, Paszkowski-Rogacz M, Brux M, Blanck C, Meyer M, Momburg F, Buchholz F, Theis M. EMBO Rep. 2020 Dec 3;21(12):e50155. doi: 10.15252/embr.202050155. Epub 2020 Oct 15. PubMed |
Cell softness regulates tumorigenicity and stemness of cancer cells. Lv J, Liu Y, Cheng F, Li J, Zhou Y, Zhang T, Zhou N, Li C, Wang Z, Ma L, Liu M, Zhu Q, Liu X, Tang K, Ma J, Zhang H, Xie J, Fang Y, Zhang H, Wang N, Liu Y, Huang B. EMBO J. 2021 Jan 15;40(2):e106123. doi: 10.15252/embj.2020106123. Epub 2020 Dec 4. PubMed |
Interferon-gamma induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation.
Yu M, Peng Z, Qin M, Liu Y, Wang J, Zhang C, Lin J, Dong T, Wang L, Li S, Yang Y, Xu S, Guo W, Zhang X, Shi M, Peng H, Luo X, Zhang H, Zhang L, Li Y, Yang XP, Sun S.
Mol Cell. 2021 Feb 13. pii: S1097-2765(21)00010-1. doi: 10.1016/j.molcel.2021.01.010.
PubMed
Associated Plasmids |
Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases. Fukuda K, Shimura C, Miura H, Tanigawa A, Suzuki T, Dohmae N, Hiratani I, Shinkai Y. Commun Biol. 2021 May 13;4(1):571. doi: 10.1038/s42003-021-02089-y. PubMed |
CRISPR mediated targeting of DUX4 distal regulatory element represses DUX4 target genes dysregulated in Facioscapulohumeral muscular dystrophy. Das S, Chadwick BP. Sci Rep. 2021 Jun 15;11(1):12598. doi: 10.1038/s41598-021-92096-0. PubMed |
Green Light Antinociceptive and Reversal of Thermal and Mechanical Hypersensitivity Effects Rely on Endogenous Opioid System Stimulation. Martin LF, Moutal A, Cheng K, Washington SM, Calligaro H, Goel V, Kranz T, Largent-Milnes TM, Khanna R, Patwardhan A, Ibrahim MM. J Pain. 2021 Dec;22(12):1646-1656. doi: 10.1016/j.jpain.2021.05.006. Epub 2021 Jun 19. PubMed |
A cost efficient protocol to introduce epitope tags by CRISPR-Cas9 mediated gene knock-in with asymmetric semi-double stranded template. Fang Q, Shinkai Y. MethodsX. 2021 Apr 27;8:101365. doi: 10.1016/j.mex.2021.101365. eCollection 2021. PubMed |
KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer. Kim KB, Kabra A, Kim DW, Xue Y, Huang Y, Hou PC, Zhou Y, Miranda LJ, Park JI, Shi X, Bender TP, Bushweller JH, Park KS. Sci Adv. 2022 Feb 18;8(7):eabl4618. doi: 10.1126/sciadv.abl4618. Epub 2022 Feb 16. PubMed |
Mammalian HEMK1 methylates glutamine residue of the GGQ motif of mitochondrial release factors. Fang Q, Kimura Y, Shimazu T, Suzuki T, Yamada A, Dohmae N, Iwasaki S, Shinkai Y. Sci Rep. 2022 Mar 8;12(1):4104. doi: 10.1038/s41598-022-08061-y. PubMed |
Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway. Lv J, Liu Y, Mo S, Zhou Y, Chen F, Cheng F, Li C, Saimi D, Liu M, Zhang H, Tang K, Ma J, Wang Z, Zhu Q, Tong WM, Huang B. Nat Cell Biol. 2022 Mar;24(3):364-372. doi: 10.1038/s41556-022-00857-4. Epub 2022 Mar 15. PubMed |
DELE1 tracks perturbed protein import and processing in human mitochondria. Fessler E, Krumwiede L, Jae LT. Nat Commun. 2022 Apr 6;13(1):1853. doi: 10.1038/s41467-022-29479-y. PubMed |
Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance. Ito H, Navratilova E, Vagnerova B, Watanabe M, Kopruszinski C, Moreira de Souza LH, Yue X, Ikegami D, Moutal A, Patwardhan A, Khanna R, Yamazaki M, Guerrero M, Rosen H, Roberts E, Neugebauer V, Dodick DW, Porreca F. Brain. 2023 Mar 1;146(3):1186-1199. doi: 10.1093/brain/awac153. PubMed |
Dendritic peptide-conjugated polymeric nanovectors for non-toxic delivery of plasmid DNA and enhanced non-viral transfection of immune cells. Yi S, Kim SY, Vincent MP, Yuk SA, Bobbala S, Du F, Scott EA. iScience. 2022 Jun 8;25(7):104555. doi: 10.1016/j.isci.2022.104555. eCollection 2022 Jul 15. PubMed |
PRC2-Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1-Targeted Therapy via Enhanced Viral Mimicry. Patel AJ, Warda S, Maag JLV, Misra R, Miranda-Roman MA, Pachai MR, Lee CJ, Li D, Wang N, Bayshtok G, Fishinevich E, Meng Y, Wong EWP, Yan J, Giff E, Pappalardi MB, McCabe MT, Fletcher JA, Rudin CM, Chandarlapaty S, Scandura JM, Koche RP, Glass JL, Antonescu CR, Zheng D, Chen Y, Chi P. Cancer Discov. 2022 Sep 2;12(9):2120-2139. doi: 10.1158/2159-8290.CD-21-1671. PubMed |
Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses. Yan J, Chen Y, Patel AJ, Warda S, Lee CJ, Nixon BG, Wong EW, Miranda-Roman MA, Yang N, Wang Y, Pachai MR, Sher J, Giff E, Tang F, Khurana E, Singer S, Liu Y, Galbo PM Jr, Maag JL, Koche RP, Zheng D, Antonescu CR, Deng L, Li MO, Chen Y, Chi P. J Clin Invest. 2022 Sep 1;132(17):e153437. doi: 10.1172/JCI153437. PubMed |
Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAF(V600E) inhibition resistance in melanoma. Zhang ZY, Ding Y, Ezhilarasan R, Lhakhang T, Wang Q, Yang J, Modrek AS, Zhang H, Tsirigos A, Futreal A, Draetta GF, Verhaak RGW, Sulman EP. Cell Discov. 2022 Oct 6;8(1):102. doi: 10.1038/s41421-022-00462-7. PubMed |
N-glycosylation Regulates Intrinsic IFN-gamma Resistance in Colorectal Cancer: Implications for Immunotherapy. Krug J, Rodrian G, Petter K, Yang H, Khoziainova S, Guo W, Benard A, Merkel S, Gellert S, Maschauer S, Spermann M, Waldner M, Bailey P, Pilarsky C, Liebl A, Tripal P, Christoph J, Naschberger E, Croner R, Schellerer VS, Becker C, Hartmann A, Tuting T, Prante O, Grutzmann R, Grivennikov SI, Sturzl M, Britzen-Laurent N. Gastroenterology. 2023 Mar;164(3):392-406.e5. doi: 10.1053/j.gastro.2022.11.018. Epub 2022 Nov 17. PubMed |
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