GFP-UBR5 ∆HECT Citations (4)
Originally described in: TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes.Gudjonsson T, Altmeyer M, Savic V, Toledo L, Dinant C, Grofte M, Bartkova J, Poulsen M, Oka Y, Bekker-Jensen S, Mailand N, Neumann B, Heriche JK, Shearer R, Saunders D, Bartek J, Lukas J, Lukas C Cell. 2012 Aug 17;150(4):697-709. doi: 10.1016/j.cell.2012.06.039. Epub 2012 Aug 9. PubMed Journal
Articles Citing GFP-UBR5 ∆HECT
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The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia.
Shearer RF, Frikstad KM, McKenna J, McCloy RA, Deng N, Burgess A, Stokke T, Patzke S, Saunders DN.
Mol Biol Cell. 2018 May 9:mbcE17040248. doi: 10.1091/mbc.E17-04-0248.
PubMed
Associated Plasmids |
| The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients. Koyuncu S, Saez I, Lee HJ, Gutierrez-Garcia R, Pokrzywa W, Fatima A, Hoppe T, Vilchez D. Nat Commun. 2018 Jul 23;9(1):2886. doi: 10.1038/s41467-018-05320-3. PubMed |
| The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells. Saez I, Gerbracht JV, Koyuncu S, Lee HJ, Horn M, Kroef V, Denzel MS, Dieterich C, Gehring NH, Vilchez D. FEBS Lett. 2020 Jan;594(1):175-188. doi: 10.1002/1873-3468.13559. Epub 2019 Aug 8. PubMed |
| UBR5 targets tumor suppressor CDC73 proteolytically to promote aggressive breast cancer. Xiang G, Wang S, Chen L, Song M, Song X, Wang H, Zhou P, Ma X, Yu J. Cell Death Dis. 2022 May 12;13(5):451. doi: 10.1038/s41419-022-04914-6. PubMed |
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