pCDNA-3xHA-hTERT Citations (10)

Originally described in: Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly.
Venteicher AS, Meng Z, Mason PJ, Veenstra TD, Artandi SE Cell. 2008 Mar 21;132(6):945-57. doi: 10.1016/j.cell.2008.01.019. PubMed Journal

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Articles Citing pCDNA-3xHA-hTERT

Articles
A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition. Stockklausner C, Raffel S, Klermund J, Bandapalli OR, Beier F, Brummendorf TH, Burger F, Sauer SW, Hoffmann GF, Lorenz H, Tagliaferri L, Nowak D, Hofmann WK, Buergermeister R, Kerber C, Rausch T, Korbel JO, Luke B, Trumpp A, Kulozik AE. Aging (Albany NY). 2015 Nov;7(11):911-27. PubMed
A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters. Kang HJ, Cui Y, Yin H, Scheid A, Hendricks WP, Schmidt J, Sekulic A, Kong D, Trent JM, Gokhale V, Mao H, Hurley LH. J Am Chem Soc. 2016 Oct 5. PubMed
P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment. Chen RJ, Wu PH, Ho CT, Way TD, Pan MH, Chen HM, Ho YS, Wang YJ. Cell Death Dis. 2017 Aug 10;8(8):e2985. doi: 10.1038/cddis.2017.333. PubMed
RIF1 promotes human epithelial ovarian cancer growth and progression via activating human telomerase reverse transcriptase expression. Liu YB, Mei Y, Long J, Zhang Y, Hu DL, Zhou HH. J Exp Clin Cancer Res. 2018 Aug 3;37(1):182. doi: 10.1186/s13046-018-0854-8. PubMed
Increased expression of NAF1 contributes to malignant phenotypes of glioma cells through promoting protein synthesis and associates with poor patient survival. Wei J, Yang Q, Shi J, Shi B, Ji M, Hou P. Oncogenesis. 2019 Apr 1;8(4):25. doi: 10.1038/s41389-019-0134-2. PubMed
SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing. Kroustallaki P, Lirussi L, Carracedo S, You P, Esbensen QY, Gotz A, Jobert L, Alsoe L, Saetrom P, Gagos S, Nilsen H. Cell Rep. 2019 Aug 13;28(7):1690-1702.e10. doi: 10.1016/j.celrep.2019.07.040. PubMed
Telomere dysfunction instigates inflammation in inflammatory bowel disease. Chakravarti D, Lee R, Multani AS, Santoni A, Keith Z, Hsu WH, Chang K, Reyes L, Rashid A, Wu CJ, Li J, Zhang J, Shim HS, Chandra K, Deng P, Spring DJ, Nielsen OH, Riis LB, Mayigegowda KK, Blutt SE, Zhang J, Younes M, DuPont A, Thirumurthi S, Vilar E, Estes MK, Colla S, Shroyer NF, DePinho RA. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29). pii: 2024853118. doi: 10.1073/pnas.2024853118. PubMed
Derivation of the Immortalized Cell Line UM51-PrePodo-hTERT and Its Responsiveness to Angiotensin II and Activation of the RAAS Pathway. Erichsen L, Kloss LDF, Thimm C, Bohndorf M, Schichel K, Wruck W, Adjaye J. Cells. 2023 Jan 17;12(3):342. doi: 10.3390/cells12030342. PubMed
Thymidine nucleotide metabolism controls human telomere length. Mannherz W, Agarwal S. Nat Genet. 2023 Apr;55(4):568-580. doi: 10.1038/s41588-023-01339-5. Epub 2023 Mar 23. PubMed
TERT Expression Induces Resistance to BRAF and MEK Inhibitors in BRAF-Mutated Melanoma In Vitro. Delyon J, Vallet A, Bernard-Cacciarella M, Kuzniak I, Reger de Moura C, Louveau B, Jouenne F, Mourah S, Lebbe C, Dumaz N. Cancers (Basel). 2023 May 24;15(11):2888. doi: 10.3390/cancers15112888. PubMed

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