pET21a-alpha-synuclein Citations (19)
Originally described in: MJFF plasmidsUnpublished
Articles Citing pET21a-alpha-synuclein
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| Cardiolipin exposure on the outer mitochondrial membrane modulates alpha-synuclein. Ryan T, Bamm VV, Stykel MG, Coackley CL, Humphries KM, Jamieson-Williams R, Ambasudhan R, Mosser DD, Lipton SA, Harauz G, Ryan SD. Nat Commun. 2018 Feb 26;9(1):817. doi: 10.1038/s41467-018-03241-9. PubMed |
| Nitration of microtubules blocks axonal mitochondrial transport in a human pluripotent stem cell model of Parkinson's disease. Stykel MG, Humphries K, Kirby MP, Czaniecki C, Wang T, Ryan T, Bamm V, Ryan SD. FASEB J. 2018 Oct;32(10):5350-5364. doi: 10.1096/fj.201700759RR. Epub 2018 Apr 24. PubMed |
| pTSara-NatB, an improved N-terminal acetylation system for recombinant protein expression in E. coli. Rovere M, Powers AE, Patel DS, Bartels T. PLoS One. 2018 Jul 11;13(7):e0198715. doi: 10.1371/journal.pone.0198715. eCollection 2018. PubMed |
| E46K-like alpha-synuclein mutants increase lipid interactions and disrupt membrane selectivity. Rovere M, Powers AE, Jiang H, Pitino JC, Fonseca-Ornelas L, Patel DS, Achille A, Langen R, Varkey J, Bartels T. J Biol Chem. 2019 Jun 21;294(25):9799-9812. doi: 10.1074/jbc.RA118.006551. Epub 2019 May 2. PubMed |
| A functionalized hydroxydopamine quinone links thiol modification to neuronal cell death. Farzam A, Chohan K, Strmiskova M, Hewitt SJ, Park DS, Pezacki JP, Ozcelik D. Redox Biol. 2020 Jan;28:101377. doi: 10.1016/j.redox.2019.101377. Epub 2019 Nov 9. PubMed |
| Cholesterol-containing lipid nanodiscs promote an alpha-synuclein binding mode that accelerates oligomerization. Jakubec M, Barias E, Furse S, Govasli ML, George V, Turcu D, Iashchishyn IA, Morozova-Roche LA, Halskau O. FEBS J. 2021 Mar;288(6):1887-1905. doi: 10.1111/febs.15551. Epub 2020 Sep 26. PubMed |
| Functionalization of amyloid fibrils via the Bri2 BRICHOS domain. Biverstal H, Kumar R, Schellhaus AK, Sarr M, Dantuma NP, Abelein A, Johansson J. Sci Rep. 2020 Dec 10;10(1):21765. doi: 10.1038/s41598-020-78732-1. PubMed |
A protease protection assay for the detection of internalized alpha-synuclein pre-formed fibrils.
Jarvela TS, Chaplot K, Lindberg I.
PLoS One. 2021 Jan 26;16(1):e0241161. doi: 10.1371/journal.pone.0241161. eCollection 2021.
PubMed
Associated Plasmids |
| N-terminal acetylation does not alter alpha-synuclein's interfacial properties. Mohapatra A, Chaudhary N. Int J Biol Macromol. 2021 Mar 31;174:69-76. doi: 10.1016/j.ijbiomac.2021.01.147. Epub 2021 Jan 23. PubMed |
| Tau induces formation of alpha-synuclein filaments with distinct molecular conformations. Hojjatian A, Dasari AKR, Sengupta U, Taylor D, Daneshparvar N, Yeganeh FA, Dillard L, Michael B, Griffin RG, Borgnia MJ, Kayed R, Taylor KA, Lim KH. Biochem Biophys Res Commun. 2021 May 21;554:145-150. doi: 10.1016/j.bbrc.2021.03.091. Epub 2021 Mar 30. PubMed |
| alpha-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of alpha-synuclein pathology. Stykel MG, Humphries KM, Kamski-Hennekam E, Buchner-Duby B, Porte-Trachsel N, Ryan T, Coackley CL, Bamm VV, Harauz G, Ryan SD. Cell Rep. 2021 May 11;35(6):109099. doi: 10.1016/j.celrep.2021.109099. PubMed |
| Polymyxin B accelerates the alpha-synuclein aggregation. Mohapatra A, Bohara VS, Kumar S, Chaudhary N. Biophys Chem. 2021 Oct;277:106628. doi: 10.1016/j.bpc.2021.106628. Epub 2021 Jun 3. PubMed |
| Altered conformation of alpha-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson's disease. Fonseca-Ornelas L, Viennet T, Rovere M, Jiang H, Liu L, Nuber S, Ericsson M, Arthanari H, Selkoe DJ. Cell Rep. 2021 Jul 6;36(1):109333. doi: 10.1016/j.celrep.2021.109333. PubMed |
| Library-Derived Peptide Aggregation Modulators of Parkinson's Disease Early-Onset alpha-Synuclein Variants. Watt KJC, Meade RM, Williams RJ, Mason JM. ACS Chem Neurosci. 2022 Jun 15;13(12):1790-1804. doi: 10.1021/acschemneuro.2c00190. Epub 2022 May 25. PubMed |
| Constitutive Endolysosomal Perforation in Neurons allows Induction of alpha-Synuclein Aggregation by Internalized Pre-Formed Fibrils. Sanyal A, Scanavachi G, Somerville E, Saminathan A, Nair A, Oikonomou A, Hatzakis NS, Kirchhausen T. bioRxiv [Preprint]. 2024 Jan 1:2023.12.30.573738. doi: 10.1101/2023.12.30.573738. PubMed |
| In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric alpha-synuclein. Huang W, Liu J, Le S, Yao M, Shi Y, Yan J. APL Bioeng. 2024 Mar 1;8(1):016114. doi: 10.1063/5.0188714. eCollection 2024 Mar. PubMed |
| Understanding the Modulation of alpha-Synuclein Fibrillation by N-Acetyl Aspartate: A Brain Metabolite. Khan T, Waseem R, Shahid M, Ansari J, Hassan MI, Shamsi A, Islam A. ACS Omega. 2024 Feb 29;9(10):12262-12271. doi: 10.1021/acsomega.4c00595. eCollection 2024 Mar 12. PubMed |
| Characterization of alpha-synuclein oligomers formed in the presence of lipid vesicles. Dasari AKR, Sengupta U, Viverette E, Borgnia MJ, Kayed R, Lim KH. Biochem Biophys Rep. 2024 Mar 19;38:101687. doi: 10.1016/j.bbrep.2024.101687. eCollection 2024 Jul. PubMed |
| Discovery of potent inhibitors of alpha-synuclein aggregation using structure-based iterative learning. Horne RI, Andrzejewska EA, Alam P, Brotzakis ZF, Srivastava A, Aubert A, Nowinska M, Gregory RC, Staats R, Possenti A, Chia S, Sormanni P, Ghetti B, Caughey B, Knowles TPJ, Vendruscolo M. Nat Chem Biol. 2024 May;20(5):634-645. doi: 10.1038/s41589-024-01580-x. Epub 2024 Apr 17. PubMed |
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