sgRNA with U6 promoter Citations (7)
Originally described in: Efficient genome editing in Caenorhabditis elegans by CRISPR-targeted homologous recombination.Chen C, Fenk LA, de Bono M Nucleic Acids Res. 2013 Sep 5. PubMed Journal
Articles Citing sgRNA with U6 promoter
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A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease. Yan S, Tu Z, Liu Z, Fan N, Yang H, Yang S, Yang W, Zhao Y, Ouyang Z, Lai C, Yang H, Li L, Liu Q, Shi H, Xu G, Zhao H, Wei H, Pei Z, Li S, Lai L, Li XJ. Cell. 2018 May 3;173(4):989-1002.e13. doi: 10.1016/j.cell.2018.03.005. Epub 2018 Mar 29. PubMed |
Efficient base editing for multiple genes and loci in pigs using base editors. Xie J, Ge W, Li N, Liu Q, Chen F, Yang X, Huang X, Ouyang Z, Zhang Q, Zhao Y, Liu Z, Gou S, Wu H, Lai C, Fan N, Jin Q, Shi H, Liang Y, Lan T, Quan L, Li X, Wang K, Lai L. Nat Commun. 2019 Jun 28;10(1):2852. doi: 10.1038/s41467-019-10421-8. PubMed |
Eliminating predictable DNA off-target effects of cytosine base editor by using dual guiders including sgRNA and TALE. Zhou J, Liu Y, Wei Y, Zheng S, Gou S, Chen T, Yang Y, Lan T, Chen M, Liao Y, Zhang Q, Tang C, Liu Y, Wu Y, Peng X, Gao M, Wang J, Zhang K, Lai L, Zou Q. Mol Ther. 2022 Jul 6;30(7):2443-2451. doi: 10.1016/j.ymthe.2022.04.010. Epub 2022 Apr 20. PubMed |
Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation. Jin Q, Liu X, Zhuang Z, Huang J, Gou S, Shi H, Zhao Y, Ouyang Z, Liu Z, Li L, Mao J, Ge W, Chen F, Yu M, Guan Y, Ye Y, Tang C, Huang R, Wang K, Lai L. Genome Biol. 2023 Jan 17;24(1):8. doi: 10.1186/s13059-023-02851-x. PubMed |
Mini-PE, a prime editor with compact Cas9 and truncated reverse transcriptase. Lan T, Chen H, Tang C, Wei Y, Liu Y, Zhou J, Zhuang Z, Zhang Q, Chen M, Zhou X, Chi Y, Wang J, He Y, Lai L, Zou Q. Mol Ther Nucleic Acids. 2023 Aug 18;33:890-897. doi: 10.1016/j.omtn.2023.08.018. eCollection 2023 Sep 12. PubMed |
Enhancing prime editor flexibility with coiled-coil heterodimers. Mu S, Chen H, Li Q, Gou S, Liu X, Wang J, Zheng W, Chen M, Jin Q, Lai L, Wang K, Shi H. Genome Biol. 2024 Apr 26;25(1):108. doi: 10.1186/s13059-024-03257-z. PubMed |
Exonuclease editor promotes precision of gene editing in mammalian cells. Shi H, Li L, Mu S, Gou S, Liu X, Chen F, Chen M, Jin Q, Lai L, Wang K. BMC Biol. 2024 May 20;22(1):119. doi: 10.1186/s12915-024-01918-w. PubMed |
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