pC1-HyPer-Red Citations (14)
Originally described in: Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide.Ermakova YG, Bilan DS, Matlashov ME, Mishina NM, Markvicheva KN, Subach OM, Subach FV, Bogeski I, Hoth M, Enikolopov G, Belousov VV Nat Commun. 2014 Oct 21;5:5222. doi: 10.1038/ncomms6222. PubMed Journal
Articles Citing pC1-HyPer-Red
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2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by HO-dependent JNK activation in cancer cells. Sun W, Bao J, Lin W, Gao H, Zhao W, Zhang Q, Leung CH, Ma DL, Lu J, Chen X. Free Radic Biol Med. 2016 Jan 21;92:61-77. doi: 10.1016/j.freeradbiomed.2016.01.014. PubMed |
Local Generation and Imaging of Hydrogen Peroxide in Living Cells.
Bogdanova YA, Schultz C, Belousov VV.
Curr Protoc Chem Biol. 2017 Jun 19;9(2):117-127. doi: 10.1002/cpch.20.
PubMed
Associated Plasmids |
Peroxiredoxin 6 mediates Galphai protein-coupled receptor inactivation by cJun kinase. Schattauer SS, Land BB, Reichard KL, Abraham AD, Burgeno LM, Kuhar JR, Phillips PEM, Ong SE, Chavkin C. Nat Commun. 2017 Sep 29;8(1):743. doi: 10.1038/s41467-017-00791-2. PubMed |
Which Antioxidant System Shapes Intracellular H2O2 Gradients? Mishina NM, Bogdanova YA, Ermakova YG, Panova AS, Kotova DA, Bilan DS, Steinhorn B, Arner ESJ, Michel T, Belousov VV. Antioxid Redox Signal. 2019 Sep 20;31(9):664-670. doi: 10.1089/ars.2018.7697. Epub 2019 Apr 24. PubMed |
Reactive oxygen species (ROS) generation is stimulated by kappa opioid receptor activation through phosphorylated c-Jun N-terminal kinase and inhibited by p38 mitogen-activated protein kinase (MAPK) activation. Schattauer SS, Bedini A, Summers F, Reilly-Treat A, Andrews MM, Land BB, Chavkin C. J Biol Chem. 2019 Nov 8;294(45):16884-16896. doi: 10.1074/jbc.RA119.009592. Epub 2019 Oct 1. PubMed |
Diurnal oscillations of endogenous H2O2 sustained by p66(Shc) regulate circadian clocks. Pei JF, Li XK, Li WQ, Gao Q, Zhang Y, Wang XM, Fu JQ, Cui SS, Qu JH, Zhao X, Hao DL, Ju D, Liu N, Carroll KS, Yang J, Zhang EE, Cao JM, Chen HZ, Liu DP. Nat Cell Biol. 2019 Dec;21(12):1553-1564. doi: 10.1038/s41556-019-0420-4. Epub 2019 Nov 25. PubMed |
Ultrasensitive Genetically Encoded Indicator for Hydrogen Peroxide Identifies Roles for the Oxidant in Cell Migration and Mitochondrial Function.
Pak VV, Ezerina D, Lyublinskaya OG, Pedre B, Tyurin-Kuzmin PA, Mishina NM, Thauvin M, Young D, Wahni K, Martinez Gache SA, Demidovich AD, Ermakova YG, Maslova YD, Shokhina AG, Eroglu E, Bilan DS, Bogeski I, Michel T, Vriz S, Messens J, Belousov VV.
Cell Metab. 2020 Mar 3;31(3):642-653.e6. doi: 10.1016/j.cmet.2020.02.003.
PubMed
Associated Plasmids |
Chalcone suppresses tumor growth through NOX4-IRE1alpha sulfonation-RIDD-miR-23b axis. Kim HK, Lee HY, Riaz TA, Bhattarai KR, Chaudhary M, Ahn JH, Jeong J, Kim HR, Chae HJ. Redox Biol. 2021 Apr;40:101853. doi: 10.1016/j.redox.2021.101853. Epub 2021 Jan 6. PubMed |
The peptide secreted at the water to land transition in a model amphibian has antioxidant effects. Barbosa EA, Placido A, Moreira DC, Albuquerque L, Dematei A, Silva-Carvalho AE, Cabral WF, Bao SN, Saldanha-Araujo F, Kuckelhaus SAS, Borges TK, Portugal CC, Socodato R, Teixeira C, Lima FCDA, Batagin-Neto A, Sebben A, Eaton P, Gomes P, Brand GD, Relvas JB, Kato MJ, Leite JRSA. Proc Biol Sci. 2021 Nov 10;288(1962):20211531. doi: 10.1098/rspb.2021.1531. Epub 2021 Nov 10. PubMed |
NERNST: a genetically-encoded ratiometric non-destructive sensing tool to estimate NADP(H) redox status in bacterial, plant and animal systems. Molinari PE, Krapp AR, Weiner A, Beyer HM, Kondadi AK, Blomeier T, Lopez M, Bustos-Sanmamed P, Tevere E, Weber W, Reichert AS, Calcaterra NB, Beller M, Carrillo N, Zurbriggen MD. Nat Commun. 2023 Jun 6;14(1):3277. doi: 10.1038/s41467-023-38739-4. PubMed |
Structure-guided engineering of a fast genetically encoded sensor for real-time H(2)O(2) monitoring. Lee JD, Won W, Kimball K, Wang Y, Yeboah F, Evitts KM, Neiswanger C, Schattauer S, Rappleye M, Bremner SB, Chun C, Smith N, Mack DL, Young JE, Lee CJ, Chavkin C, Berndt A. bioRxiv [Preprint]. 2024 Feb 4:2024.01.31.578117. doi: 10.1101/2024.01.31.578117. PubMed |
Far-red and sensitive sensor for monitoring real time H(2)O(2) dynamics with subcellular resolution and in multi-parametric imaging applications. Lee JD, Nguyen A, Jin ZR, Moghadasi A, Gibbs CE, Wait SJ, Evitts KM, Asencio A, Bremner SB, Zuniga S, Chavan V, Williams A, Smith N, Regnier M, Young JE, Mack D, Nance E, Boyle PM, Berndt A. bioRxiv [Preprint]. 2024 Feb 8:2024.02.06.579232. doi: 10.1101/2024.02.06.579232. PubMed |
Ultra-fast genetically encoded sensor for precise real-time monitoring of physiological and pathophysiological peroxide dynamics. Berndt A, Lee J, Won W, Kimball K, Neiswanger C, Schattauer S, Wang Y, Yeboah F, Ruiz M, Evitts K, Rappleye M, Bremner S, Chun C, Smith N, Mack D, Young J, Lee CJ, Chavkin C. Res Sq [Preprint]. 2024 Mar 25:rs.3.rs-4048855. doi: 10.21203/rs.3.rs-4048855/v1. PubMed |
Far-red and sensitive sensor for monitoring real time H(2)O(2) dynamics with subcellular resolution and in multi-parametric imaging applications. Berndt A, Lee J, Nguyen A, Jin Z, Moghadasi A, Gibbs C, Wait S, Evitts K, Asencio A, Bremner S, Zuniga S, Chavan V, Williams A, Smith A, Moussavi-Harami F, Regnier M, Young J, Mack D, Nance E, Boyle P. Res Sq [Preprint]. 2024 Apr 17:rs.3.rs-3974015. doi: 10.21203/rs.3.rs-3974015/v1. PubMed |
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