pMLM3705 Citations (16)
Originally described in: CRISPR RNA-guided activation of endogenous human genes.Maeder ML, Linder SJ, Cascio VM, Fu Y, Ho QH, Joung JK Nat Methods. 2013 Jul 25. doi: 10.1038/nmeth.2598. PubMed Journal
Articles Citing pMLM3705
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A prominent and conserved role for YY1 in Xist transcriptional activation. Makhlouf M, Ouimette JF, Oldfield A, Navarro P, Neuillet D, Rougeulle C. Nat Commun. 2014 Sep 11;5:4878. doi: 10.1038/ncomms5878. PubMed |
Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display.
Shechner DM, Hacisuleyman E, Younger ST, Rinn JL.
Nat Methods. 2015 Jul;12(7):664-70. doi: 10.1038/nmeth.3433. Epub 2015 Jun 1.
PubMed
Associated Plasmids |
Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome. Muller M, Lee CM, Gasiunas G, Davis TH, Cradick TJ, Siksnys V, Bao G, Cathomen T, Mussolino C. Mol Ther. 2015 Dec 14. doi: 10.1038/mt.2015.218. PubMed |
Engineering Synthetic Gene Circuits in Living Cells with CRISPR Technology. Jusiak B, Cleto S, Perez-Pinera P, Lu TK. Trends Biotechnol. 2016 Jan 22. pii: S0167-7799(15)00274-7. doi: 10.1016/j.tibtech.2015.12.014. PubMed |
Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner. Cano-Rodriguez D, Gjaltema RA, Jilderda LJ, Jellema P, Dokter-Fokkens J, Ruiters MH, Rots MG. Nat Commun. 2016 Aug 10;7:12284. doi: 10.1038/ncomms12284. PubMed |
Rewiring human cellular input-output using modular extracellular sensors.
Schwarz KA, Daringer NM, Dolberg TB, Leonard JN.
Nat Chem Biol. 2016 Dec 12. doi: 10.1038/nchembio.2253.
PubMed
Associated Plasmids |
Synthetic Promoters and Transcription Factors for Heterologous Protein Expression in Saccharomyces cerevisiae. Machens F, Balazadeh S, Mueller-Roeber B, Messerschmidt K. Front Bioeng Biotechnol. 2017 Oct 19;5:63. doi: 10.3389/fbioe.2017.00063. eCollection 2017. PubMed |
Establishment of Cell Lines Stably Expressing dCas9-Fusions to Address Kinetics of Epigenetic Editing.
Goubert D, Koncz M, Kiss A, Rots MG.
Methods Mol Biol. 2018;1767:395-415. doi: 10.1007/978-1-4939-7774-1_22.
PubMed
Associated Plasmids |
Enhancing the Translational Capacity of E. coli by Resolving the Codon Bias. Lipinszki Z, Vernyik V, Farago N, Sari T, Puskas LG, Blattner FR, Posfai G, Gyorfy Z. ACS Synth Biol. 2018 Nov 16;7(11):2656-2664. doi: 10.1021/acssynbio.8b00332. Epub 2018 Nov 2. PubMed |
Targeted removal of epigenetic barriers during transcriptional reprogramming. Baumann V, Wiesbeck M, Breunig CT, Braun JM, Koferle A, Ninkovic J, Gotz M, Stricker SH. Nat Commun. 2019 May 9;10(1):2119. doi: 10.1038/s41467-019-10146-8. PubMed |
KRAB-Induced Heterochromatin Effectively Silences PLOD2 Gene Expression in Somatic Cells and is Resilient to TGFbeta1 Activation. Gjaltema RAF, Goubert D, Huisman C, Pilar Garcia Tobilla CD, Koncz M, Jellema PG, Wu D, Brouwer U, Kiss A, Verschure PJ, Bank RA, Rots MG. Int J Mol Sci. 2020 May 21;21(10). pii: ijms21103634. doi: 10.3390/ijms21103634. PubMed |
Impact of the Epigenetically Regulated Hoxa-5 Gene in Neural Differentiation from Human Adipose-Derived Stem Cells. Hernandez R, Jimenez-Luna C, Ortiz R, Setien F, Lopez M, Perazzoli G, Esteller M, Berdasco M, Prados J, Melguizo C. Biology (Basel). 2021 Aug 19;10(8). pii: biology10080802. doi: 10.3390/biology10080802. PubMed |
RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis. Tognoli ML, Vlahov N, Steenbeek S, Grawenda AM, Eyres M, Cano-Rodriguez D, Scrace S, Kartsonaki C, von Kriegsheim A, Willms E, Wood MJ, Rots MG, van Rheenen J, O'Neill E, Pankova D. EMBO J. 2021 Oct 18;40(20):e107680. doi: 10.15252/embj.2021107680. Epub 2021 Sep 17. PubMed |
Functional Validation of the Putative Oncogenic Activity of PLAU. Sarno F, Goubert D, Logie E, Rutten MGS, Koncz M, Deben C, Niemarkt AE, Altucci L, Verschure PJ, Kiss A, Berghe WV, Rots MG. Biomedicines. 2022 Dec 30;11(1):102. doi: 10.3390/biomedicines11010102. PubMed |
PhiReX 2.0: A Programmable and Red Light-Regulated CRISPR-dCas9 System for the Activation of Endogenous Genes in Saccharomyces cerevisiae. Machens F, Ran G, Ruehmkorff C, Meyer Auf der Heyde J, Mueller-Roeber B, Hochrein L. ACS Synth Biol. 2023 Apr 21;12(4):1046-1057. doi: 10.1021/acssynbio.2c00517. Epub 2023 Apr 4. PubMed |
Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells. Wu DD, Lau ATY, Xu YM, Reinders-Luinge M, Koncz M, Kiss A, Timens W, Rots MG, Hylkema MN. Epigenetics. 2023 Dec;18(1):2175522. doi: 10.1080/15592294.2023.2175522. Epub 2023 Feb 22. PubMed |
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