pRK5-EGFP-Tau P301L Citations (17)
Originally described in: Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration.Hoover BR, Reed MN, Su J, Penrod RD, Kotilinek LA, Grant MK, Pitstick R, Carlson GA, Lanier LM, Yuan LL, Ashe KH, Liao D Neuron. 2010 Dec 22;68(6):1067-81. doi: 10.1016/j.neuron.2010.11.030. PubMed Journal
Articles Citing pRK5-EGFP-Tau P301L
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Lysosomal LAMP1 immunoreactivity exists in both diffuse and neuritic amyloid plaques in the human hippocampus. Hassiotis S, Manavis J, Blumbergs PC, Hattersley KJ, Carosi JM, Kamei M, Sargeant TJ. Eur J Neurosci. 2018 May;47(9):1043-1053. doi: 10.1111/ejn.13913. Epub 2018 Apr 2. PubMed |
The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer's disease model. Fan SJ, Huang FI, Liou JP, Yang CR. Cell Death Dis. 2018 May 29;9(6):655. doi: 10.1038/s41419-018-0688-5. PubMed |
5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes. Lee HY, Fan SJ, Huang FI, Chao HY, Hsu KC, Lin TE, Yeh TK, Lai MJ, Li YH, Huang HL, Yang CR, Liou JP. J Med Chem. 2018 Aug 23;61(16):7087-7102. doi: 10.1021/acs.jmedchem.8b00151. Epub 2018 Aug 9. PubMed |
Pathogenic tau does not drive activation of the unfolded protein response. Pitera AP, Asuni AA, O'Connor V, Deinhardt K. J Biol Chem. 2019 Jun 21;294(25):9679-9688. doi: 10.1074/jbc.RA119.008263. Epub 2019 May 3. PubMed |
Moscatilin Ameliorates Tau Phosphorylation and Cognitive Deficits in Alzheimer's Disease Models. Huang JM, Huang FI, Yang CR. J Nat Prod. 2019 Jul 26;82(7):1979-1988. doi: 10.1021/acs.jnatprod.9b00375. Epub 2019 Jul 10. PubMed |
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models. Song JX, Malampati S, Zeng Y, Durairajan SSK, Yang CB, Tong BC, Iyaswamy A, Shang WB, Sreenivasmurthy SG, Zhu Z, Cheung KH, Lu JH, Tang C, Xu N, Li M. Aging Cell. 2020 Feb;19(2):e13069. doi: 10.1111/acel.13069. Epub 2019 Dec 19. PubMed |
NeuroDefend, a novel Chinese medicine, attenuates amyloid-beta and tau pathology in experimental Alzheimer's disease models. Iyaswamy A, Krishnamoorthi SK, Song JX, Yang CB, Kaliyamoorthy V, Zhang H, Sreenivasmurthy SG, Malampati S, Wang ZY, Zhu Z, Tong BC, Cheung KH, Lu JH, Durairajan SSK, Li M. J Food Drug Anal. 2020 Jan;28(1):132-146. doi: 10.1016/j.jfda.2019.09.004. Epub 2019 Oct 8. PubMed |
Tau induces PSD95-neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration. Park L, Hochrainer K, Hattori Y, Ahn SJ, Anfray A, Wang G, Uekawa K, Seo J, Palfini V, Blanco I, Acosta D, Eliezer D, Zhou P, Anrather J, Iadecola C. Nat Neurosci. 2020 Sep;23(9):1079-1089. doi: 10.1038/s41593-020-0686-7. Epub 2020 Aug 10. PubMed |
The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model. Yuste-Checa P, Trinkaus VA, Riera-Tur I, Imamoglu R, Schaller TF, Wang H, Dudanova I, Hipp MS, Bracher A, Hartl FU. Nat Commun. 2021 Aug 11;12(1):4863. doi: 10.1038/s41467-021-25060-1. PubMed |
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation. Torres-Garcia L, P Domingues JM, Brandi E, Haikal C, Mudannayake JM, Bras IC, Gerhardt E, Li W, Svanbergsson A, Outeiro TF, Gouras GK, Li JY. Sci Rep. 2022 Feb 22;12(1):2987. doi: 10.1038/s41598-022-06846-9. PubMed |
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models. Iyaswamy A, Wang X, Krishnamoorthi S, Kaliamoorthy V, Sreenivasmurthy SG, Kumar Durairajan SS, Song JX, Tong BC, Zhu Z, Su CF, Liu J, Cheung KH, Lu JH, Tan JQ, Li HW, Wong MS, Li M. Redox Biol. 2022 May;51:102280. doi: 10.1016/j.redox.2022.102280. Epub 2022 Mar 8. PubMed |
Zinc enhances autophagic flux and lysosomal function through transcription factor EB activation and V-ATPase assembly. Kim KR, Park SE, Hong JY, Koh JY, Cho DH, Hwang JJ, Kim YH. Front Cell Neurosci. 2022 Sep 29;16:895750. doi: 10.3389/fncel.2022.895750. eCollection 2022. PubMed |
Chaperoning activity of the cyclophilin family prevents tau aggregation. Hill SE, Esquivel AR, Ospina SR, Rahal LM, Dickey CA, Blair LJ. Protein Sci. 2022 Nov;31(11):e4448. doi: 10.1002/pro.4448. PubMed |
Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. Bhagat R, Minaya MA, Renganathan A, Mehra M, Marsh J, Martinez R, Nana AL, Spina S, Seeley WW, Grinberg LT, Karch CM. medRxiv [Preprint]. 2023 Mar 1:2023.02.27.23286548. doi: 10.1101/2023.02.27.23286548. PubMed |
Neuroinflammation-Modulating Agent SB1617 Enhances LC3-Associated Phagocytosis to Mitigate Tau Pathology. Cho H, Choi BY, Shin YH, Suh SW, Park SB. ACS Chem Neurosci. 2023 Dec 6;14(23):4139-4152. doi: 10.1021/acschemneuro.3c00508. Epub 2023 Nov 28. PubMed |
Behavioral and Neurophysiological Implications of Pathological Human Tau Expression in Serotonin Neurons. Khan NS, Uribe Isaza J, Rouhi N, Jamani NF, Jabeen S, Gill AK, Tsutsui M, Visser F, Sargin D. ACS Chem Neurosci. 2024 Mar 6;15(5):932-943. doi: 10.1021/acschemneuro.3c00626. Epub 2024 Feb 20. PubMed |
Tau regulates Arc stability in neuronal dendrites via a proteasome-sensitive but ubiquitin-independent pathway. Yakout DW, Shroff A, Wei W, Thaker V, Allen ZD, Sajish M, Nazarko TY, Mabb AM. J Biol Chem. 2024 May;300(5):107237. doi: 10.1016/j.jbc.2024.107237. Epub 2024 Mar 27. PubMed |
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