pT7-gRNA Citations (56)
Originally described in: Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system.Jao LE, Wente SR, Chen W Proc Natl Acad Sci U S A. 2013 Aug 5. PubMed Journal
Articles Citing pT7-gRNA
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| Disruptive CHD8 mutations define a subtype of autism early in development. Bernier R, Golzio C, Xiong B, Stessman HA, Coe BP, Penn O, Witherspoon K, Gerdts J, Baker C, Vulto-van Silfhout AT, Schuurs-Hoeijmakers JH, Fichera M, Bosco P, Buono S, Alberti A, Failla P, Peeters H, Steyaert J, Vissers LE, Francescatto L, Mefford HC, Rosenfeld JA, Bakken T, O'Roak BJ, Pawlus M, Moon R, Shendure J, Amaral DG, Lein E, Rankin J, Romano C, de Vries BB, Katsanis N, Eichler EE. Cell. 2014 Jul 17;158(2):263-76. doi: 10.1016/j.cell.2014.06.017. Epub 2014 Jul 3. PubMed |
| Efficient homologous recombination-mediated genome engineering in zebrafish using TALE nucleases. Shin J, Chen J, Solnica-Krezel L. Development. 2014 Oct;141(19):3807-18. doi: 10.1242/dev.108019. Epub 2014 Sep 5. PubMed |
| Targeted mutagenesis in Atlantic salmon (Salmo salar L.) using the CRISPR/Cas9 system induces complete knockout individuals in the F0 generation. Edvardsen RB, Leininger S, Kleppe L, Skaftnesmo KO, Wargelius A. PLoS One. 2014 Sep 25;9(9):e108622. doi: 10.1371/journal.pone.0108622. eCollection 2014. PubMed |
| Evaluation of the in vivo safety profiles of Rictor inhibition using a zebrafish model. Cao Y, Jiang L, Zhao L, Zhou X, Wang N, Zhang P, Tang Y, Zhou J. Curr Pharm Des. 2015;21(12):1645-53. PubMed |
| Matrix metalloproteinase 9 modulates collagen matrices and wound repair. LeBert DC, Squirrell JM, Rindy J, Broadbridge E, Lui Y, Zakrzewska A, Eliceiri KW, Meijer AH, Huttenlocher A. Development. 2015 Jun 15;142(12):2136-46. doi: 10.1242/dev.121160. Epub 2015 May 26. PubMed |
| Biological Roles of Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1), HSD11B2, and Glucocorticoid Receptor (NR3C1) in Sheep Conceptus Elongation. Brooks K, Burns G, Spencer TE. Biol Reprod. 2015 Aug;93(2):38. doi: 10.1095/biolreprod.115.130757. Epub 2015 Jun 17. PubMed |
| Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation. Cortes M, Liu SY, Kwan W, Alexa K, Goessling W, North TE. Stem Cell Reports. 2015 Oct 13;5(4):471-9. doi: 10.1016/j.stemcr.2015.08.010. Epub 2015 Sep 10. PubMed |
| Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Kaizuka T, Mizushima N. Mol Cell Biol. 2015 Dec 7;36(4):585-95. doi: 10.1128/MCB.01005-15. PubMed |
| Homology Directed Knockin of Point Mutations in the Zebrafish tardbp and fus Genes in ALS Using the CRISPR/Cas9 System. Armstrong GA, Liao M, You Z, Lissouba A, Chen BE, Drapeau P. PLoS One. 2016 Mar 1;11(3):e0150188. doi: 10.1371/journal.pone.0150188. eCollection 2016. PubMed |
| Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia. Bolar NA, Golzio C, Zivna M, Hayot G, Van Hemelrijk C, Schepers D, Vandeweyer G, Hoischen A, Huyghe JR, Raes A, Matthys E, Sys E, Azou M, Gubler MC, Praet M, Van Camp G, McFadden K, Pediaditakis I, Pristoupilova A, Hodanova K, Vyletal P, Hartmannova H, Stranecky V, Hulkova H, Baresova V, Jedlickova I, Sovova J, Hnizda A, Kidd K, Bleyer AJ, Spong RS, Vande Walle J, Mortier G, Brunner H, Van Laer L, Kmoch S, Katsanis N, Loeys BL. Am J Hum Genet. 2016 Jul 7;99(1):174-87. doi: 10.1016/j.ajhg.2016.05.028. PubMed |
| Multiplex conditional mutagenesis in zebrafish using the CRISPR/Cas system. Yin L, Maddison LA, Chen W. Methods Cell Biol. 2016;135:3-17. doi: 10.1016/bs.mcb.2016.04.018. Epub 2016 May 30. PubMed |
| miR-19b Regulates Ventricular Action Potential Duration in Zebrafish. Benz A, Kossack M, Auth D, Seyler C, Zitron E, Juergensen L, Katus HA, Hassel D. Sci Rep. 2016 Nov 2;6:36033. doi: 10.1038/srep36033. PubMed |
| Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase. Sasaki T, Lian S, Khan A, Llop JR, Samuelson AV, Chen W, Klionsky DJ, Kishi S. Autophagy. 2017 Feb;13(2):386-403. doi: 10.1080/15548627.2016.1256934. Epub 2016 Nov 22. PubMed |
| The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6. Antosova B, Smolikova J, Klimova L, Lachova J, Bendova M, Kozmikova I, Machon O, Kozmik Z. PLoS Genet. 2016 Dec 5;12(12):e1006441. doi: 10.1371/journal.pgen.1006441. eCollection 2016 Dec. PubMed |
| Biochemical characterization of a medaka (Oryzias latipes) orthologue for mammalian Factor XIII and establishment of a gene-edited mutant. Horimizu R, Ogawa R, Watanabe Y, Tatsukawa H, Kinoshita M, Hashimoto H, Hitomi K. FEBS J. 2017 Jun 27. doi: 10.1111/febs.14153. PubMed |
| Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish. Wehner D, Tsarouchas TM, Michael A, Haase C, Weidinger G, Reimer MM, Becker T, Becker CG. Nat Commun. 2017 Jul 25;8(1):126. doi: 10.1038/s41467-017-00143-0. PubMed |
| A shared Runx1-bound Zbtb16 enhancer directs innate and innate-like lymphoid lineage development. Mao AP, Ishizuka IE, Kasal DN, Mandal M, Bendelac A. Nat Commun. 2017 Oct 16;8(1):863. doi: 10.1038/s41467-017-00882-0. PubMed |
| G protein-coupled estrogen receptor regulates embryonic heart rate in zebrafish. Romano SN, Edwards HE, Souder JP, Ryan KJ, Cui X, Gorelick DA. PLoS Genet. 2017 Oct 24;13(10):e1007069. doi: 10.1371/journal.pgen.1007069. eCollection 2017 Oct. PubMed |
| Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning. Pelliccia JL, Jindal GA, Burdine RD. Elife. 2017 Nov 15;6. pii: 28635. doi: 10.7554/eLife.28635. PubMed |
| Nuclear Androgen Receptor Regulates Testes Organization and Oocyte Maturation in Zebrafish. Crowder CM, Lassiter CS, Gorelick DA. Endocrinology. 2018 Feb 1;159(2):980-993. doi: 10.1210/en.2017-00617. PubMed |
| Targeted deletion of the zebrafish actin-bundling protein L-plastin (lcp1). Kell MJ, Riccio RE, Baumgartner EA, Compton ZJ, Pecorin PJ, Mitchell TA, Topczewski J, LeClair EE. PLoS One. 2018 Jan 2;13(1):e0190353. doi: 10.1371/journal.pone.0190353. eCollection 2018. PubMed |
| Damage-induced reactive oxygen species regulate vimentin and dynamic collagen-based projections to mediate wound repair. LeBert D, Squirrell JM, Freisinger C, Rindy J, Golenberg N, Frecentese G, Gibson A, Eliceiri KW, Huttenlocher A. Elife. 2018 Jan 16;7. pii: 30703. doi: 10.7554/eLife.30703. PubMed |
| Higher susceptibility to osmolality of the medaka (Oryzias latipes) mutants in orthologue genes of mammalian skin transglutaminases. Watanabe Y, Furukawa E, Tatsukawa H, Hashimoto H, Kamei Y, Taniguchi Y, Hitomi K. Biosci Biotechnol Biochem. 2018 Jul;82(7):1165-1168. doi: 10.1080/09168451.2018.1453294. Epub 2018 Mar 23. PubMed |
| Blocking fatty acid-fueled mROS production within macrophages alleviates acute gouty inflammation. Hall CJ, Sanderson LE, Lawrence LM, Pool B, van der Kroef M, Ashimbayeva E, Britto D, Harper JL, Lieschke GJ, Astin JW, Crosier KE, Dalbeth N, Crosier PS. J Clin Invest. 2018 May 1;128(5):1752-1771. doi: 10.1172/JCI94584. Epub 2018 Mar 26. PubMed |
| Distinct interactions of Sox5 and Sox10 in fate specification of pigment cells in medaka and zebrafish. Nagao Y, Takada H, Miyadai M, Adachi T, Seki R, Kamei Y, Hara I, Taniguchi Y, Naruse K, Hibi M, Kelsh RN, Hashimoto H. PLoS Genet. 2018 Apr 5;14(4):e1007260. doi: 10.1371/journal.pgen.1007260. eCollection 2018 Apr. PubMed |
| The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish. Lai JKH, Collins MM, Uribe V, Jimenez-Amilburu V, Gunther S, Maischein HM, Stainier DYR. Development. 2018 May 17;145(10). pii: 145/10/dev159210. doi: 10.1242/dev.159210. PubMed |
| Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development. Astone M, Lai JKH, Dupont S, Stainier DYR, Argenton F, Vettori A. Sci Rep. 2018 Jul 5;8(1):10189. doi: 10.1038/s41598-018-27657-x. PubMed |
| Robust activation of microhomology-mediated end joining for precision gene editing applications. Ata H, Ekstrom TL, Martinez-Galvez G, Mann CM, Dvornikov AV, Schaefbauer KJ, Ma AC, Dobbs D, Clark KJ, Ekker SC. PLoS Genet. 2018 Sep 12;14(9):e1007652. doi: 10.1371/journal.pgen.1007652. eCollection 2018 Sep. PubMed |
| Color opponency with a single kind of bistable opsin in the zebrafish pineal organ. Wada S, Shen B, Kawano-Yamashita E, Nagata T, Hibi M, Tamotsu S, Koyanagi M, Terakita A. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11310-11315. doi: 10.1073/pnas.1802592115. Epub 2018 Oct 15. PubMed |
Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization.
Murdoch CC, Espenschied ST, Matty MA, Mueller O, Tobin DM, Rawls JF.
PLoS Pathog. 2019 Mar 7;15(3):e1007381. doi: 10.1371/journal.ppat.1007381. eCollection 2019 Mar.
PubMed
Associated Plasmids |
| Adamts9 is necessary for ovarian development in zebrafish. Carter NJ, Roach ZA, Byrnes MM, Zhu Y. Gen Comp Endocrinol. 2019 Jun 1;277:130-140. doi: 10.1016/j.ygcen.2019.04.003. Epub 2019 Apr 2. PubMed |
| The development of CRISPR for a mollusc establishes the formin Lsdia1 as the long-sought gene for snail dextral/sinistral coiling. Abe M, Kuroda R. Development. 2019 May 14;146(9). pii: dev.175976. doi: 10.1242/dev.175976. PubMed |
| Genome-wide strategies reveal target genes of Npas4l associated with vascular development in zebrafish. Marass M, Beisaw A, Gerri C, Luzzani F, Fukuda N, Gunther S, Kuenne C, Reischauer S, Stainier DYR. Development. 2019 Jun 3;146(11). pii: dev.173427. doi: 10.1242/dev.173427. PubMed |
| CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes. Datsomor AK, Zic N, Li K, Olsen RE, Jin Y, Vik JO, Edvardsen RB, Grammes F, Wargelius A, Winge P. Sci Rep. 2019 May 17;9(1):7533. doi: 10.1038/s41598-019-43862-8. PubMed |
| EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells. Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. Nat Cell Biol. 2019 Jun;21(6):721-730. doi: 10.1038/s41556-019-0330-5. Epub 2019 May 20. PubMed |
| Agouti-Related Protein 2 Is a New Player in the Teleost Stress Response System. Shainer I, Michel M, Marquart GD, Bhandiwad AA, Zmora N, Ben-Moshe Livne Z, Zohar Y, Hazak A, Mazon Y, Forster D, Hollander-Cohen L, Cone RD, Burgess HA, Gothilf Y. Curr Biol. 2019 Jun 17;29(12):2009-2019.e7. doi: 10.1016/j.cub.2019.05.021. Epub 2019 Jun 6. PubMed |
| The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis. Bose P, Tremblay E, Maois C, Narasimhan V, Armstrong GAB, Liao M, Parker JA, Robitaille R, Wen XY, Barden C, Drapeau P. Neurotherapeutics. 2019 Oct;16(4):1149-1166. doi: 10.1007/s13311-019-00765-w. PubMed |
| A critical role of VMP1 in lipoprotein secretion. Morishita H, Zhao YG, Tamura N, Nishimura T, Kanda Y, Sakamaki Y, Okazaki M, Li D, Mizushima N. Elife. 2019 Sep 17;8. pii: 48834. doi: 10.7554/eLife.48834. PubMed |
| Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation. Oprisoreanu AM, Smith HL, Arya S, Webster R, Zhong Z, Wehner D, Cardozo MJ, Becker T, Talbot K, Becker CG. Cell Rep. 2019 Oct 29;29(5):1082-1098.e10. doi: 10.1016/j.celrep.2019.09.033. PubMed |
| CRISPR/Cas9-mediated editing of Delta5 and Delta6 desaturases impairs Delta8-desaturation and docosahexaenoic acid synthesis in Atlantic salmon (Salmo salar L.). Datsomor AK, Olsen RE, Zic N, Madaro A, Bones AM, Edvardsen RB, Wargelius A, Winge P. Sci Rep. 2019 Nov 15;9(1):16888. doi: 10.1038/s41598-019-53316-w. PubMed |
| Inflammation and matrix metalloproteinase 9 (Mmp-9) regulate photoreceptor regeneration in adult zebrafish. Silva NJ, Nagashima M, Li J, Kakuk-Atkins L, Ashrafzadeh M, Hyde DR, Hitchcock PF. Glia. 2020 Jul;68(7):1445-1465. doi: 10.1002/glia.23792. Epub 2020 Feb 8. PubMed |
| Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Luciani A, Schumann A, Berquez M, Chen Z, Nieri D, Failli M, Debaix H, Festa BP, Tokonami N, Raimondi A, Cremonesi A, Carrella D, Forny P, Kolker S, Diomedi Camassei F, Diaz F, Moraes CT, Di Bernardo D, Baumgartner MR, Devuyst O. Nat Commun. 2020 Feb 20;11(1):970. doi: 10.1038/s41467-020-14729-8. PubMed |
| Defining endogenous barcoding sites for CRISPR/Cas9-based cell lineage tracing in zebrafish. Ye C, Chen Z, Liu Z, Wang F, He X. J Genet Genomics. 2020 Feb 20;47(2):85-91. doi: 10.1016/j.jgg.2019.11.012. Epub 2020 Feb 7. PubMed |
| Gene disruption of medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2) causes movement retardation. Watanabe Y, Okuya K, Takada Y, Kinoshita M, Yokoi S, Chisada S, Kamei Y, Tatsukawa H, Yamamoto N, Abe H, Hashimoto H, Hitomi K. J Biochem. 2020 Apr 6. pii: 5816600. doi: 10.1093/jb/mvaa038. PubMed |
| 1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos. Chen XK, Kwan JS, Chang RC, Ma AC. Autophagy. 2020 Apr 22:1-10. doi: 10.1080/15548627.2020.1755119. PubMed |
| Deletion of SREBF1, a Functional Bone-Muscle Pleiotropic Gene, Alters Bone Density and Lipid Signaling in Zebrafish. Shochat C, Wang Z, Mo C, Nelson S, Donaka R, Huang J, Karasik D, Brotto M. Endocrinology. 2021 Jan 1;162(1). pii: 5929645. doi: 10.1210/endocr/bqaa189. PubMed |
Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder.
Morishita H, Kanda Y, Kaizuka T, Chino H, Nakao K, Miki Y, Taketomi Y, Guan JL, Murakami M, Aiba A, Mizushima N.
Cell Rep. 2020 Dec 8;33(10):108477. doi: 10.1016/j.celrep.2020.108477.
PubMed
Associated Plasmids |
| Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions. Templehof H, Moshe N, Avraham-Davidi I, Yaniv K. JCI Insight. 2021 Jul 8;6(13). pii: e130399. doi: 10.1172/jci.insight.130399. PubMed |
| Autophagy coordinates chondrocyte development and early joint formation in zebrafish. Moss JJ, Wirth M, Tooze SA, Lane JD, Hammond CL. FASEB J. 2021 Nov;35(11):e22002. doi: 10.1096/fj.202101167R. PubMed |
| Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development. Torregrosa-Carrion R, Pineiro-Sabaris R, Siguero-Alvarez M, Grego-Bessa J, Luna-Zurita L, Fernandes VS, MacGrogan D, Stainier DYR, de la Pompa JL. Sci Adv. 2021 Nov 12;7(46):eabj5445. doi: 10.1126/sciadv.abj5445. Epub 2021 Nov 12. PubMed |
| Loss of circadian rhythmicity in bdnf knockout zebrafish larvae. D'Agostino Y, Frigato E, Noviello TMR, Toni M, Frabetti F, Cigliano L, Ceccarelli M, Sordino P, Cerulo L, Bertolucci C, D'Aniello S. iScience. 2022 Mar 11;25(4):104054. doi: 10.1016/j.isci.2022.104054. eCollection 2022 Apr 15. PubMed |
| An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates. America M, Bostaille N, Eubelen M, Martin M, Stainier DYR, Vanhollebeke B. Cell Rep. 2022 May 31;39(9):110902. doi: 10.1016/j.celrep.2022.110902. PubMed |
| Zebrafish mutants reveal unexpected role of Lrp5 in osteoclast regulation. Khrystoforova I, Shochat-Carvalho C, Harari R, Henke K, Woronowicz K, Harris MP, Karasik D. Front Endocrinol (Lausanne). 2022 Sep 2;13:985304. doi: 10.3389/fendo.2022.985304. eCollection 2022. PubMed |
| Local angiogenic interplay of Vegfc/d and Vegfa controls brain region-specific emergence of fenestrated capillaries. Parab S, Card OA, Chen Q, America M, Buck LD, Quick RE, Horrigan WF, Levkowitz G, Vanhollebeke B, Matsuoka RL. Elife. 2023 May 16;12:e86066. doi: 10.7554/eLife.86066. PubMed |
| Cfdp1 Is Essential for Cardiac Development and Function. Giardoglou P, Deloukas P, Dedoussis G, Beis D. Cells. 2023 Aug 3;12(15):1994. doi: 10.3390/cells12151994. PubMed |
| A brain-specific angiogenic mechanism enabled by tip cell specialization. Schevenels G, Cabochette P, America M, Vandenborne A, De Grande L, Guenther S, He L, Dieu M, Christou B, Vermeersch M, Germano RFV, Perez-Morga D, Renard P, Martin M, Vanlandewijck M, Betsholtz C, Vanhollebeke B. Nature. 2024 Apr;628(8009):863-871. doi: 10.1038/s41586-024-07283-6. Epub 2024 Apr 3. PubMed |
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