HA Depdc5 pRK5 Citations (3)

Originally described in: A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. PubMed Journal

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Articles Citing HA Depdc5 pRK5

Articles
Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Kim JS, Ro SH, Kim M, Park HW, Semple IA, Park H, Cho US, Wang W, Guan KL, Karin M, Lee JH. Sci Rep. 2015 Mar 30;5:9502. doi: 10.1038/srep09502. PubMed
Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition. Figlia G, Muller S, Hagenston AM, Kleber S, Roiuk M, Quast JP, Ten Bosch N, Carvajal Ibanez D, Mauceri D, Martin-Villalba A, Teleman AA. Nat Cell Biol. 2022 Sep;24(9):1407-1421. doi: 10.1038/s41556-022-00977-x. Epub 2022 Sep 12. PubMed
CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth. Yin S, Liu L, Ball LE, Wang Y, Bedford MT, Duncan SA, Wang H, Gan W. Cell Rep. 2023 Apr 25;42(4):112316. doi: 10.1016/j.celrep.2023.112316. Epub 2023 Mar 29. PubMed

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