pEYFP-C1-Drp1 Citations (16)
Originally described in: The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis.Frank S, Gaume B, Bergmann-Leitner ES, Leitner WW, Robert EG, Catez F, Smith CL, Youle RJ Dev Cell. 2001 Oct;1(4):515-25. PubMed Journal
Articles Citing pEYFP-C1-Drp1
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Nestin regulates proliferation and invasion of gastrointestinal stromal tumor cells by altering mitochondrial dynamics. Wang J, Cai J, Huang Y, Ke Q, Wu B, Wang S, Han X, Wang T, Wang Y, Li W, Lao C, Song W, Xiang AP. Oncogene. 2015 Oct 5. doi: 10.1038/onc.2015.370. PubMed |
ERK/Drp1-dependent mitochondrial fission is involved in the MSC-induced drug resistance of T-cell acute lymphoblastic leukemia cells. Cai J, Wang J, Huang Y, Wu H, Xia T, Xiao J, Chen X, Li H, Qiu Y, Wang Y, Wang T, Xia H, Zhang Q, Xiang AP. Cell Death Dis. 2016 Nov 10;7(11):e2459. doi: 10.1038/cddis.2016.370. PubMed |
Inhibition of ERK-Drp1 signaling and mitochondria fragmentation alleviates IGF-IIR-induced mitochondria dysfunction during heart failure. Huang CY, Lai CH, Kuo CH, Chiang SF, Pai PY, Lin JY, Chang CF, Viswanadha VP, Kuo WW, Huang CY. J Mol Cell Cardiol. 2018 Sep;122:58-68. doi: 10.1016/j.yjmcc.2018.08.006. Epub 2018 Aug 9. PubMed |
Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission.
Kamerkar SC, Kraus F, Sharpe AJ, Pucadyil TJ, Ryan MT.
Nat Commun. 2018 Dec 7;9(1):5239. doi: 10.1038/s41467-018-07543-w.
PubMed
Associated Plasmids |
Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming. Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, Tregnago C, Corrado M, Pigazzi M, Barnaba V, Tripodo C, Matarese G, Piconese S, Campello S. Cell Rep. 2018 Dec 11;25(11):3059-3073.e10. doi: 10.1016/j.celrep.2018.11.018. PubMed |
BCL-XL directly retrotranslocates the monomeric BAK. Wang B, Mai Z, Du M, Wang L, Yang F, Ma Y, Wang X, Chen T. Cell Signal. 2019 Sep;61:1-9. doi: 10.1016/j.cellsig.2019.05.001. Epub 2019 May 3. PubMed |
Quantifying the inhibitory effect of Bcl-xl on the action of Mff using live-cell fluorescence imaging. Ma Y, Du M, Yang F, Mai Z, Zhang C, Qu W, Wang B, Wang X, Chen T. FEBS Open Bio. 2019 Dec;9(12):2041-2051. doi: 10.1002/2211-5463.12739. Epub 2019 Nov 15. PubMed |
Neurotrophins induce fission of mitochondria along embryonic sensory axons. Armijo-Weingart L, Ketschek A, Sainath R, Pacheco A, Smith GM, Gallo G. Elife. 2019 Dec 2;8. pii: 49494. doi: 10.7554/eLife.49494. PubMed |
Mitochondrial division inhibitor 1 disrupts oligodendrocyte Ca(2+) homeostasis and mitochondrial function. Ruiz A, Quintela-Lopez T, Sanchez-Gomez MV, Gaminde-Blasco A, Alberdi E, Matute C. Glia. 2020 Sep;68(9):1743-1756. doi: 10.1002/glia.23802. Epub 2020 Feb 14. PubMed |
Bcl-xL inhibits PINK1/Parkin-dependent mitophagy by preventing mitochondrial Parkin accumulation. Yu S, Du M, Yin A, Mai Z, Wang Y, Zhao M, Wang X, Chen T. Int J Biochem Cell Biol. 2020 May;122:105720. doi: 10.1016/j.biocel.2020.105720. Epub 2020 Feb 20. PubMed |
JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction. Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, Antonucci Y, Di Daniele A, Caicci F, Caruana I, Soriano ME, Pigazzi M, Locatelli F, Cecconi F, Campello S. Cell Death Differ. 2020 Apr 28. pii: 10.1038/s41418-020-0540-1. doi: 10.1038/s41418-020-0540-1. PubMed |
Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer. Humphries BA, Cutter AC, Buschhaus JM, Chen YC, Qyli T, Palagama DSW, Eckley S, Robison TH, Bevoor A, Chiang B, Haley HR, Sahoo S, Spinosa PC, Neale DB, Boppisetti J, Sahoo D, Ghosh P, Lahann J, Ross BD, Yoon E, Luker KE, Luker GD. Breast Cancer Res. 2020 Jun 5;22(1):60. doi: 10.1186/s13058-020-01301-x. PubMed |
Mitofusin 2 but not mitofusin 1 mediates Bcl-XL-induced mitochondrial aggregation. Du M, Yu S, Su W, Zhao M, Yang F, Liu Y, Mai Z, Wang Y, Wang X, Chen T. J Cell Sci. 2020 Oct 26;133(20):jcs245001. doi: 10.1242/jcs.245001. PubMed |
TDP-43 and PINK1 mediate CHCHD10(S59L) mutation-induced defects in Drosophila and in vitro. Baek M, Choe YJ, Bannwarth S, Kim J, Maitra S, Dorn GW 2nd, Taylor JP, Paquis-Flucklinger V, Kim NC. Nat Commun. 2021 Mar 26;12(1):1924. doi: 10.1038/s41467-021-22145-9. PubMed |
Activation of Drp1 promotes fatty acids-induced metabolic reprograming to potentiate Wnt signaling in colon cancer. Xiong X, Hasani S, Young LEA, Rivas DR, Skaggs AT, Martinez R, Wang C, Weiss HL, Gentry MS, Sun RC, Gao T. Cell Death Differ. 2022 Mar 24. pii: 10.1038/s41418-022-00974-5. doi: 10.1038/s41418-022-00974-5. PubMed |
Regorafenib induces Bim-mediated intrinsic apoptosis by blocking AKT-mediated FOXO3a nuclear export. Sun B, Chen H, Wang X, Chen T. Cell Death Discov. 2023 Jan 31;9(1):37. doi: 10.1038/s41420-023-01338-9. PubMed |
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