EJ2GFP-puro Citations (13)
Originally described in: Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.Bennardo N, Cheng A, Huang N, Stark JM PLoS Genet. 2008 Jun 27;4(6):e1000110. doi: 10.1371/journal.pgen.1000110. PubMed Journal
Articles Citing EJ2GFP-puro
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CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling. Narayanaswamy PB, Tkachuk S, Haller H, Dumler I, Kiyan Y. Cell Death Dis. 2016 Sep 29;7(9):e2383. doi: 10.1038/cddis.2016.291. PubMed |
Targeting the MALAT1/PARP1/LIG3 complex induces DNA damage and apoptosis in multiple myeloma.
Hu Y, Lin J, Fang H, Fang J, Li C, Chen W, Liu S, Ondrejka S, Gong Z, Reu F, Maciejewski J, Yi Q, Zhao JJ.
Leukemia. 2018 Mar 22. pii: 10.1038/s41375-018-0104-2. doi: 10.1038/s41375-018-0104-2.
PubMed
Associated Plasmids |
Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation. Biechonski S, Olender L, Zipin-Roitman A, Yassin M, Aqaqe N, Marcu-Malina V, Rall-Scharpf M, Trottier M, Meyn MS, Wiesmuller L, Beider K, Raz Y, Grisaru D, Nagler A, Milyavsky M. Sci Rep. 2018 Apr 17;8(1):6071. doi: 10.1038/s41598-018-24440-w. PubMed |
Activation of Wnt signaling promotes olaparib resistant ovarian cancer. Yamamoto TM, McMellen A, Watson ZL, Aguilera J, Ferguson R, Nurmemmedov E, Thakar T, Moldovan GL, Kim H, Cittelly DM, Joglar AM, Brennecke EP, Wilson H, Behbakht K, Sikora MJ, Bitler BG. Mol Carcinog. 2019 Jun 10. doi: 10.1002/mc.23064. PubMed |
The RNA transport factor PHAX is required for proper histone H2AX expression and DNA damage response. Machitani M, Taniguchi I, McCloskey A, Suzuki T, Ohno M. RNA. 2020 Nov;26(11):1716-1725. doi: 10.1261/rna.074625.120. Epub 2020 Aug 5. PubMed |
Metastasis Suppressor NME1 Modulates Choice of Double-Strand Break Repair Pathways in Melanoma Cells by Enhancing Alternative NHEJ while Inhibiting NHEJ and HR. Puts G, Jarrett S, Leonard M, Matsangos N, Snyder D, Wang Y, Vincent R, Portney B, Abbotts R, McLaughlin L, Zalzman M, Rassool F, Kaetzel D. Int J Mol Sci. 2020 Aug 17;21(16). pii: ijms21165896. doi: 10.3390/ijms21165896. PubMed |
TGFbetaR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment. Le BV, Podszywalow-Bartnicka P, Maifrede S, Sullivan-Reed K, Nieborowska-Skorska M, Golovine K, Yao JC, Nejati R, Cai KQ, Caruso LB, Swatler J, Dabrowski M, Lian Z, Valent P, Paietta EM, Levine RL, Fernandez HF, Tallman MS, Litzow MR, Huang J, Challen GA, Link D, Tempera I, Wasik MA, Piwocka K, Skorski T. Cell Rep. 2020 Oct 6;33(1):108221. doi: 10.1016/j.celrep.2020.108221. PubMed |
Loss of TGFbeta signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types. Liu Q, Palomero L, Moore J, Guix I, Espin R, Aytes A, Mao JH, Paulovich AG, Whiteaker JR, Ivey RG, Iliakis G, Luo D, Chalmers AJ, Murnane J, Pujana MA, Barcellos-Hoff MH. Sci Transl Med. 2021 Feb 10;13(580). pii: 13/580/eabc4465. doi: 10.1126/scitranslmed.abc4465. PubMed |
Long noncoding RNA NIHCOLE promotes ligation efficiency of DNA double-strand breaks in hepatocellular carcinoma. Unfried JP, Marin-Baquero M, Rivera-Calzada A, Razquin N, Martin-Cuevas EM, de Braganca S, Aicart-Ramos C, McCoy C, Prats-Mari L, Arribas-Bosacoma R, Lee L, Caruso S, Zucman-Rossi J, Sangro B, Williams G, Moreno-Herrero F, Llorca O, Lees-Miller SP, Fortes P. Cancer Res. 2021 Jul 28. pii: 0008-5472.CAN-21-0463. doi: 10.1158/0008-5472.CAN-21-0463. PubMed |
Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication. Scarpa M, Kapoor S, Tvedte ES, Doshi KA, Zou YS, Singh P, Lee JK, Chatterjee A, Ali MKM, Bromley RE, Hotopp JCD, Rassool FV, Baer MR. Oncotarget. 2021 Aug 31;12(18):1763-1779. doi: 10.18632/oncotarget.28042. eCollection 2021 Aug 31. PubMed |
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin. Caracciolo D, Juli G, Riillo C, Coricello A, Vasile F, Pollastri S, Rocca R, Scionti F, Polera N, Grillone K, Arbitrio M, Staropoli N, Caparello B, Britti D, Loprete G, Costa G, Di Martino MT, Alcaro S, Tagliaferri P, Tassone P. J Transl Med. 2022 Oct 22;20(1):482. doi: 10.1186/s12967-022-03705-z. PubMed |
The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining. Fleury H, MacEachern MK, Stiefel CM, Anand R, Sempeck C, Nebenfuehr B, Maurer-Alcala K, Ball K, Proctor B 3rd, Belan O, Taylor E, Ortega R, Dodd B, Weatherly L, Dansoko D, Leung JW, Boulton SJ, Arnoult N. Mol Cell. 2023 May 4;83(9):1429-1445.e8. doi: 10.1016/j.molcel.2023.03.017. Epub 2023 Apr 11. PubMed |
Chromatin-Associated SIN3B Protects Cancer Cells from Genotoxic Stress-Induced Apoptosis and Dictates DNA Damage Repair Pathway Choice. Morales-Valencia J, Petit C, Calderon A, Saini S, David G. Mol Cancer Res. 2023 Sep 1;21(9):947-957. doi: 10.1158/1541-7786.MCR-22-0466. PubMed |
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