MLM3613 Citations (104)
Originally described in: Efficient genome editing in zebrafish using a CRISPR-Cas system.Hwang WY, Fu Y, Reyon D, Maeder ML, Tsai SQ, Sander JD, Peterson RT, Yeh JR, Joung JK Nat Biotechnol. 2013 Jan 29. doi: 10.1038/nbt.2501. PubMed Journal
Articles Citing MLM3613
Articles |
---|
Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system. Bassett AR, Tibbit C, Ponting CP, Liu JL. Cell Rep. 2013 Jul 11;4(1):220-8. doi: 10.1016/j.celrep.2013.06.020. Epub 2013 Jul 1. PubMed |
CRISPR/Cas9 mediated genome engineering in Drosophila. Bassett A, Liu JL. Methods. 2014 Sep;69(2):128-36. doi: 10.1016/j.ymeth.2014.02.019. Epub 2014 Feb 24. PubMed |
CRISPR/Cas-mediated targeted mutagenesis in Daphnia magna. Nakanishi T, Kato Y, Matsuura T, Watanabe H. PLoS One. 2014 May 30;9(5):e98363. doi: 10.1371/journal.pone.0098363. eCollection 2014. PubMed |
Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform.
Yoshimi K, Kaneko T, Voigt B, Mashimo T.
Nat Commun. 2014 Jun 26;5:4240. doi: 10.1038/ncomms5240.
PubMed
Associated Plasmids |
Understanding functional miRNA-target interactions in vivo by site-specific genome engineering. Bassett AR, Azzam G, Wheatley L, Tibbit C, Rajakumar T, McGowan S, Stanger N, Ewels PA, Taylor S, Ponting CP, Liu JL, Sauka-Spengler T, Fulga TA. Nat Commun. 2014 Aug 19;5:4640. doi: 10.1038/ncomms5640. PubMed |
TALEN and CRISPR/Cas9-mediated genome editing in the early-branching metazoan Nematostella vectensis.
Ikmi A, McKinney SA, Delventhal KM, Gibson MC.
Nat Commun. 2014 Nov 24;5:5486. doi: 10.1038/ncomms6486.
PubMed
Associated Plasmids |
High-throughput genome editing and phenotyping facilitated by high resolution melting curve analysis. Thomas HR, Percival SM, Yoder BK, Parant JM. PLoS One. 2014 Dec 11;9(12):e114632. doi: 10.1371/journal.pone.0114632. eCollection 2014. PubMed |
A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate. Harel I, Benayoun BA, Machado B, Singh PP, Hu CK, Pech MF, Valenzano DR, Zhang E, Sharp SC, Artandi SE, Brunet A. Cell. 2015 Feb 26;160(5):1013-26. doi: 10.1016/j.cell.2015.01.038. Epub 2015 Feb 12. PubMed |
Generating and identifying axolotls with targeted mutations using Cas9 RNA-guided nuclease. Flowers GP, Crews CM. Methods Mol Biol. 2015;1290:279-95. doi: 10.1007/978-1-4939-2495-0_22. PubMed |
In vivo functional analysis of the Drosophila melanogaster nicotinic acetylcholine receptor Dalpha6 using the insecticide spinosad. Somers J, Nguyen J, Lumb C, Batterham P, Perry T. Insect Biochem Mol Biol. 2015 Mar 4. pii: S0965-1748(15)00046-6. doi: 10.1016/j.ibmb.2015.01.018. PubMed |
Heritable CRISPR/Cas9-mediated genome editing in the yellow fever mosquito, Aedes aegypti. Dong S, Lin J, Held NL, Clem RJ, Passarelli AL, Franz AW. PLoS One. 2015 Mar 27;10(3):e0122353. doi: 10.1371/journal.pone.0122353. eCollection 2015. PubMed |
Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti. Kistler KE, Vosshall LB, Matthews BJ. Cell Rep. 2015 Apr 7;11(1):51-60. doi: 10.1016/j.celrep.2015.03.009. Epub 2015 Mar 26. PubMed |
A Quantitative System for Studying Metastasis Using Transparent Zebrafish. Heilmann S, Ratnakumar K, Langdon EM, Kansler ER, Kim IS, Campbell NR, Perry EB, McMahon AJ, Kaufman CK, van Rooijen E, Lee W, Iacobuzio-Donahue CA, Hynes RO, Zon LI, Xavier JB, White RM. Cancer Res. 2015 Oct 15;75(20):4272-82. doi: 10.1158/0008-5472.CAN-14-3319. Epub 2015 Aug 17. PubMed |
Hypocretin neuron-specific transcriptome profiling identifies the sleep modulator Kcnh4a. Yelin-Bekerman L, Elbaz I, Diber A, Dahary D, Gibbs-Bar L, Alon S, Lerer-Goldshtein T, Appelbaum L. Elife. 2015 Oct 1;4. pii: e08638. doi: 10.7554/eLife.08638. PubMed |
The alternative splicing factor Nova2 regulates vascular development and lumen formation. Giampietro C, Deflorian G, Gallo S, Di Matteo A, Pradella D, Bonomi S, Belloni E, Nyqvist D, Quaranta V, Confalonieri S, Bertalot G, Orsenigo F, Pisati F, Ferrero E, Biamonti G, Fredrickx E, Taveggia C, Wyatt CD, Irimia M, Di Fiore PP, Blencowe BJ, Dejana E, Ghigna C. Nat Commun. 2015 Oct 8;6:8479. doi: 10.1038/ncomms9479. PubMed |
An autoregulatory enhancer controls mammary-specific STAT5 functions. Metser G, Shin HY, Wang C, Yoo KH, Oh S, Villarino AV, O'Shea JJ, Kang K, Hennighausen L. Nucleic Acids Res. 2015 Oct 7. pii: gkv999. PubMed |
A Zebrafish Loss-of-Function Model for Human CFAP53 Mutations Reveals Its Specific Role in Laterality Organ Function. Noel ES, Momenah TS, Al-Dagriri K, Al-Suwaid A, Al-Shahrani S, Jiang H, Willekers S, Oostveen YY, Chocron S, Postma AV, Bhuiyan ZA, Bakkers J. Hum Mutat. 2016 Feb;37(2):194-200. doi: 10.1002/humu.22928. Epub 2015 Dec 2. PubMed |
Identification of the silkworm quail gene reveals a crucial role of a receptor guanylyl cyclase in larval pigmentation. Yuasa M, Kiuchi T, Banno Y, Katsuma S, Shimada T. Insect Biochem Mol Biol. 2016 Jan;68:33-40. doi: 10.1016/j.ibmb.2015.10.016. Epub 2015 Nov 10. PubMed |
CRISPR/Cas9 Promotes Functional Study of Testis Specific X-Linked Gene In Vivo. Li M, Huang R, Jiang X, Chen Y, Zhang Z, Zhang X, Liang P, Zhan S, Cao S, Songyang Z, Huang J. PLoS One. 2015 Nov 24;10(11):e0143148. doi: 10.1371/journal.pone.0143148. eCollection 2015. PubMed |
Epilepsy, Behavioral Abnormalities, and Physiological Comorbidities in Syntaxin-Binding Protein 1 (STXBP1) Mutant Zebrafish. Grone BP, Marchese M, Hamling KR, Kumar MG, Krasniak CS, Sicca F, Santorelli FM, Patel M, Baraban SC. PLoS One. 2016 Mar 10;11(3):e0151148. doi: 10.1371/journal.pone.0151148. eCollection 2016. PubMed |
Clustered regulatory interspaced short palindromic repeats (CRISPR)-mediated mutagenesis and phenotype rescue by piggyBac transgenesis in a nonmodel Drosophila species. Tanaka R, Murakami H, Ote M, Yamamoto D. Insect Mol Biol. 2016 Aug;25(4):355-61. doi: 10.1111/imb.12232. Epub 2016 Mar 25. PubMed |
Targeted candidate gene screens using CRISPR/Cas9 technology. Shah AN, Moens CB, Miller AC. Methods Cell Biol. 2016;135:89-106. doi: 10.1016/bs.mcb.2016.01.008. Epub 2016 Feb 26. PubMed |
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload. Liu JC, Liu J, Holmstrom KM, Menazza S, Parks RJ, Fergusson MM, Yu ZX, Springer DA, Halsey C, Liu C, Murphy E, Finkel T. Cell Rep. 2016 Aug 9;16(6):1561-73. doi: 10.1016/j.celrep.2016.07.011. Epub 2016 Jul 28. PubMed |
A vertebrate-specific and essential role for osterix in osteogenesis revealed by gene knockout in the teleost medaka. Yu T, Graf M, Renn J, Schartl M, Larionova D, Huysseune A, Witten PE, Winkler C. Development. 2017 Jan 15;144(2):265-271. doi: 10.1242/dev.139550. Epub 2016 Dec 19. PubMed |
Lineage-Specific and Non-specific Cytokine-Sensing Genes Respond Differentially to the Master Regulator STAT5. Zeng X, Willi M, Shin HY, Hennighausen L, Wang C. Cell Rep. 2016 Dec 20;17(12):3333-3346. doi: 10.1016/j.celrep.2016.11.079. PubMed |
Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization. Wild R, Klems A, Takamiya M, Hayashi Y, Strahle U, Ando K, Mochizuki N, van Impel A, Schulte-Merker S, Krueger J, Preau L, le Noble F. Nat Commun. 2017 Jan 10;8:13991. doi: 10.1038/ncomms13991. PubMed |
A Unique Egg Cortical Granule Localization Motif Is Required for Ovastacin Sequestration to Prevent Premature ZP2 Cleavage and Ensure Female Fertility in Mice. Xiong B, Zhao Y, Beall S, Sadusky AB, Dean J. PLoS Genet. 2017 Jan 23;13(1):e1006580. doi: 10.1371/journal.pgen.1006580. eCollection 2017 Jan. PubMed |
CRISPR-Mediated Knockout of Cybb in NSG Mice Establishes a Model of Chronic Granulomatous Disease for Human Stem-Cell Gene Therapy Transplants. Sweeney CL, Choi U, Liu C, Koontz S, Ha SK, Malech HL. Hum Gene Ther. 2017 Jul;28(7):565-575. doi: 10.1089/hum.2017.005. Epub 2017 Mar 6. PubMed |
Cutting Edge: beta-Catenin-Interacting Tcf1 Isoforms Are Essential for Thymocyte Survival but Dispensable for Thymic Maturation Transitions. Xu Z, Xing S, Shan Q, Gullicksrud JA, Bair TB, Du Y, Liu C, Xue HH. J Immunol. 2017 May 1;198(9):3404-3409. doi: 10.4049/jimmunol.1602139. Epub 2017 Mar 27. PubMed |
CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome. Shin HY, Wang C, Lee HK, Yoo KH, Zeng X, Kuhns T, Yang CM, Mohr T, Liu C, Hennighausen L. Nat Commun. 2017 May 31;8:15464. doi: 10.1038/ncomms15464. PubMed |
The role of ZKSCAN3 in the transcriptional regulation of autophagy. Pan H, Yan Y, Liu C, Finkel T. Autophagy. 2017 Jul 3;13(7):1235-1238. doi: 10.1080/15548627.2017.1320635. Epub 2017 Jun 5. PubMed |
Active nuclear transcriptome analysis reveals inflammasome-dependent mechanism for early neutrophil response to Mycobacterium marinum. Kenyon A, Gavriouchkina D, Zorman J, Napolitani G, Cerundolo V, Sauka-Spengler T. Sci Rep. 2017 Jul 26;7(1):6505. doi: 10.1038/s41598-017-06099-x. PubMed |
Modeling Dominant and Recessive Forms of Retinitis Pigmentosa by Editing Three Rhodopsin-Encoding Genes in Xenopus Laevis Using Crispr/Cas9. Feehan JM, Chiu CN, Stanar P, Tam BM, Ahmed SN, Moritz OL. Sci Rep. 2017 Jul 31;7(1):6920. doi: 10.1038/s41598-017-07153-4. PubMed |
CRISPR/Cas9-Mediated Deletion of Foxn1 in NOD/SCID/IL2rg(-/-) Mice Results in Severe Immunodeficiency. Wei X, Lai Y, Li B, Qin L, Xu Y, Lin S, Wang S, Wu Q, Liang Q, Huang G, Deng Q, Liu P, Wu D, Lai L, Yao Y, Li P. Sci Rep. 2017 Aug 10;7(1):7720. doi: 10.1038/s41598-017-08337-8. PubMed |
Fibroblast growth factor signaling is required for early somatic gonad development in zebrafish. Leerberg DM, Sano K, Draper BW. PLoS Genet. 2017 Sep 5;13(9):e1006993. doi: 10.1371/journal.pgen.1006993. eCollection 2017 Sep. PubMed |
Mutations of conserved non-coding elements of PITX2 in patients with ocular dysgenesis and developmental glaucoma. Protas ME, Weh E, Footz T, Kasberger J, Baraban SC, Levin AV, Katz LJ, Ritch R, Walter MA, Semina EV, Gould DB. Hum Mol Genet. 2017 Sep 15;26(18):3630-3638. doi: 10.1093/hmg/ddx251. PubMed |
Telomeric TERB1-TRF1 interaction is crucial for male meiosis. Long J, Huang C, Chen Y, Zhang Y, Shi S, Wu L, Liu Y, Liu C, Wu J, Lei M. Nat Struct Mol Biol. 2017 Dec;24(12):1073-1080. doi: 10.1038/nsmb.3496. Epub 2017 Oct 30. PubMed |
Optogenetic Activation of the fruitless-Labeled Circuitry in Drosophila subobscura Males Induces Mating Motor Acts. Tanaka R, Higuchi T, Kohatsu S, Sato K, Yamamoto D. J Neurosci. 2017 Nov 29;37(48):11662-11674. doi: 10.1523/JNEUROSCI.1943-17.2017. Epub 2017 Nov 6. PubMed |
Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Shin SW, Vogt EJ, Jimenez-Movilla M, Baibakov B, Dean J. Nat Commun. 2017 Nov 21;8(1):1643. doi: 10.1038/s41467-017-01387-6. PubMed |
Bombyx ortholog of the Drosophila eye color gene brown controls riboflavin transport in Malpighian tubules. Zhang H, Kiuchi T, Hirayama C, Katsuma S, Shimada T. Insect Biochem Mol Biol. 2018 Jan;92:65-72. doi: 10.1016/j.ibmb.2017.11.012. Epub 2017 Nov 28. PubMed |
Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA. Hosono Y, Niknafs YS, Prensner JR, Iyer MK, Dhanasekaran SM, Mehra R, Pitchiaya S, Tien J, Escara-Wilke J, Poliakov A, Chu SC, Saleh S, Sankar K, Su F, Guo S, Qiao Y, Freier SM, Bui HH, Cao X, Malik R, Johnson TM, Beer DG, Feng FY, Zhou W, Chinnaiyan AM. Cell. 2017 Dec 14;171(7):1559-1572.e20. doi: 10.1016/j.cell.2017.11.040. PubMed |
Unlinking the methylome pattern from nucleotide sequence, revealed by large-scale in vivo genome engineering and methylome editing in medaka fish. Cheung NKM, Nakamura R, Uno A, Kumagai M, Fukushima HS, Morishita S, Takeda H. PLoS Genet. 2017 Dec 21;13(12):e1007123. doi: 10.1371/journal.pgen.1007123. eCollection 2017 Dec. PubMed |
Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo. Eve AMJ, Smith JC. Wellcome Open Res. 2017 Nov 16;2:111. doi: 10.12688/wellcomeopenres.12394.1. eCollection 2017. PubMed |
Identification of an Intra- and Inter-specific Tear Protein Signal in Rodents. Tsunoda M, Miyamichi K, Eguchi R, Sakuma Y, Yoshihara Y, Kikusui T, Kuwahara M, Touhara K. Curr Biol. 2018 Apr 23;28(8):1213-1223.e6. doi: 10.1016/j.cub.2018.02.060. Epub 2018 Mar 29. PubMed |
rbpms2 functions in Balbiani body architecture and ovary fate. Kaufman OH, Lee K, Martin M, Rothhamel S, Marlow FL. PLoS Genet. 2018 Jul 5;14(7):e1007489. doi: 10.1371/journal.pgen.1007489. eCollection 2018 Jul. PubMed |
Glycan-Independent Gamete Recognition Triggers Egg Zinc Sparks and ZP2 Cleavage to Prevent Polyspermy. Tokuhiro K, Dean J. Dev Cell. 2018 Sep 10;46(5):627-640.e5. doi: 10.1016/j.devcel.2018.07.020. Epub 2018 Aug 16. PubMed |
Generation of Cas9 transgenic zebrafish and their application in establishing an ERV-deficient animal model. Yang Z, Chen S, Xue S, Li X, Sun Z, Yang Y, Hu X, Geng T, Cui H. Biotechnol Lett. 2018 Dec;40(11-12):1507-1518. doi: 10.1007/s10529-018-2605-5. Epub 2018 Sep 22. PubMed |
Sequential specification of oligodendrocyte lineage cells by distinct levels of Hedgehog and Notch signaling. Ravanelli AM, Kearns CA, Powers RK, Wang Y, Hines JH, Donaldson MJ, Appel B. Dev Biol. 2018 Dec 15;444(2):93-106. doi: 10.1016/j.ydbio.2018.10.004. Epub 2018 Oct 19. PubMed |
Using CRISPR/Cas9 for Gene Knockout in Immunodeficient NSG Mice. Du Y, Xie W, Zhang F, Choi U, Liu C, Sweeney CL. Methods Mol Biol. 2019;1874:139-168. doi: 10.1007/978-1-4939-8831-0_8. PubMed |
Sexual rejection via a vomeronasal receptor-triggered limbic circuit. Osakada T, Ishii KK, Mori H, Eguchi R, Ferrero DM, Yoshihara Y, Liberles SD, Miyamichi K, Touhara K. Nat Commun. 2018 Oct 26;9(1):4463. doi: 10.1038/s41467-018-07003-5. PubMed |
Ciliary Beating Compartmentalizes Cerebrospinal Fluid Flow in the Brain and Regulates Ventricular Development. Olstad EW, Ringers C, Hansen JN, Wens A, Brandt C, Wachten D, Yaksi E, Jurisch-Yaksi N. Curr Biol. 2019 Jan 21;29(2):229-241.e6. doi: 10.1016/j.cub.2018.11.059. Epub 2019 Jan 3. PubMed |
The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope. Wang Y, Chen Y, Chen J, Wang L, Nie L, Long J, Chang H, Wu J, Huang C, Lei M. Nat Commun. 2019 Feb 4;10(1):564. doi: 10.1038/s41467-019-08437-1. PubMed |
Targeted in vivo epigenome editing of H3K27me3.
Fukushima HS, Takeda H, Nakamura R.
Epigenetics Chromatin. 2019 Mar 13;12(1):17. doi: 10.1186/s13072-019-0263-z.
PubMed
Associated Plasmids |
A genetic switch for worker nutrition-mediated traits in honeybees. Roth A, Vleurinck C, Netschitailo O, Bauer V, Otte M, Kaftanoglu O, Page RE, Beye M. PLoS Biol. 2019 Mar 21;17(3):e3000171. doi: 10.1371/journal.pbio.3000171. eCollection 2019 Mar. PubMed |
Aedes aegypti Mosquitoes Detect Acidic Volatiles Found in Human Odor Using the IR8a Pathway. Raji JI, Melo N, Castillo JS, Gonzalez S, Saldana V, Stensmyr MC, DeGennaro M. Curr Biol. 2019 Apr 22;29(8):1253-1262.e7. doi: 10.1016/j.cub.2019.02.045. Epub 2019 Mar 28. PubMed |
Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies. Oppel F, Tao T, Shi H, Ross KN, Zimmerman MW, He S, Tong G, Aster JC, Look AT. PLoS Genet. 2019 Apr 10;15(4):e1008039. doi: 10.1371/journal.pgen.1008039. eCollection 2019 Apr. PubMed |
Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes. Papanikos F, Clement JAJ, Testa E, Ravindranathan R, Grey C, Dereli I, Bondarieva A, Valerio-Cabrera S, Stanzione M, Schleiffer A, Jansa P, Lustyk D, Fei JF, Adams IR, Forejt J, Barchi M, de Massy B, Toth A. Mol Cell. 2019 Jun 6;74(5):1069-1085.e11. doi: 10.1016/j.molcel.2019.03.022. Epub 2019 Apr 15. PubMed |
Neurotensin Enhances Locomotor Activity and Arousal, and Inhibits Melanin-Concentrating Hormone Signalings. Levitas-Djerbi T, Sagi D, Lebenthal-Loinger I, Lerer-Goldshtein T, Appelbaum L. Neuroendocrinology. 2019 Apr 29. pii: 000500590. doi: 10.1159/000500590. PubMed |
Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects. Geister KA, Lopez-Jimenez AJ, Houghtaling S, Ho TH, Vanacore R, Beier DR. Dis Model Mech. 2019 Jun 17;12(6). pii: dmm.037176. doi: 10.1242/dmm.037176. PubMed |
Gene Editing in Chronic Granulomatous Disease. Sweeney CL, Merling RK, De Ravin SS, Choi U, Malech HL. Methods Mol Biol. 2019;1982:623-665. doi: 10.1007/978-1-4939-9424-3_36. PubMed |
The Magnitude of IFN-gamma Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1. Petermann F, Pekowska A, Johnson CA, Jankovic D, Shih HY, Jiang K, Hudson WH, Brooks SR, Sun HW, Villarino AV, Yao C, Singleton K, Akondy RS, Kanno Y, Sher A, Casellas R, Ahmed R, O'Shea JJ. Mol Cell. 2019 Sep 19;75(6):1229-1242.e5. doi: 10.1016/j.molcel.2019.06.025. Epub 2019 Jul 31. PubMed |
ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects. Liedtke D, Orth M, Meissler M, Geuer S, Knaup S, Koblitz I, Klopocki E. Sci Rep. 2019 Sep 16;9(1):13383. doi: 10.1038/s41598-019-50055-w. PubMed |
Genomic Structure of Hstx2 Modifier of Prdm9-Dependent Hybrid Male Sterility in Mice. Lustyk D, Kinsky S, Ullrich KK, Yancoskie M, Kasikova L, Gergelits V, Sedlacek R, Chan YF, Odenthal-Hesse L, Forejt J, Jansa P. Genetics. 2019 Nov;213(3):1047-1063. doi: 10.1534/genetics.119.302554. Epub 2019 Sep 27. PubMed |
Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice. Wang Z, Xu X, Li JL, Palmer C, Maric D, Dean J. Nat Commun. 2019 Nov 15;10(1):5196. doi: 10.1038/s41467-019-13193-3. PubMed |
Neural Alterations and Hyperactivity of the Hypothalamic-Pituitary-Thyroid Axis in Oatp1c1 Deficiency. Admati I, Wasserman-Bartov T, Tovin A, Rozenblat R, Blitz E, Zada D, Lerer-Goldshtein T, Appelbaum L. Thyroid. 2020 Jan;30(1):161-174. doi: 10.1089/thy.2019.0320. PubMed |
Origin and role of the cerebrospinal fluid bidirectional flow in the central canal. Thouvenin O, Keiser L, Cantaut-Belarif Y, Carbo-Tano M, Verweij F, Jurisch-Yaksi N, Bardet PL, van Niel G, Gallaire F, Wyart C. Elife. 2020 Jan 9;9. pii: 47699. doi: 10.7554/eLife.47699. PubMed |
Systemic loss of Sarm1 protects Schwann cells from chemotoxicity by delaying axon degeneration. Tian W, Czopka T, Lopez-Schier H. Commun Biol. 2020 Jan 30;3(1):49. doi: 10.1038/s42003-020-0776-9. PubMed |
FIGLA, LHX8 and SOHLH1 transcription factor networks regulate mouse oocyte growth and differentiation. Wang Z, Liu CY, Zhao Y, Dean J. Nucleic Acids Res. 2020 Apr 17;48(7):3525-3541. doi: 10.1093/nar/gkaa101. PubMed |
EXOSC10 sculpts the transcriptome during the growth-to-maturation transition in mouse oocytes. Wu D, Dean J. Nucleic Acids Res. 2020 Jun 4;48(10):5349-5365. doi: 10.1093/nar/gkaa249. PubMed |
The interdependence of mammary-specific super-enhancers and their native promoters facilitates gene activation during pregnancy. Zeng X, Lee HK, Wang C, Achikeh P, Liu C, Hennighausen L. Exp Mol Med. 2020 Apr;52(4):682-690. doi: 10.1038/s12276-020-0425-x. Epub 2020 Apr 22. PubMed |
Generation of Acsl4 Gene Knockout Mouse Model by CRISPR/Cas9-Mediated Genome Engineering. Ren H, Hua Z, Meng J, Molenaar A, Bi Y, Cheng N, Zheng X. Crit Rev Biomed Eng. 2019;47(5):419-426. doi: 10.1615/CritRevBiomedEng.2019030342. PubMed |
Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse. Bondarieva A, Raveendran K, Telychko V, Rao HBDP, Ravindranathan R, Zorzompokou C, Finsterbusch F, Dereli I, Papanikos F, Trankner D, Schleiffer A, Fei JF, Klimova A, Ito M, Kulkarni DS, Roeder I, Hunter N, Toth A. Nat Commun. 2020 Jun 18;11(1):3101. doi: 10.1038/s41467-020-16885-3. PubMed |
Functional role of annexins in zebrafish caudal fin regeneration - A gene knockdown approach in regenerating tissue. Quoseena M, Vuppaladadium S, Hussain S, Banu S, Bharathi S, Idris MM. Biochimie. 2020 Aug;175:125-131. doi: 10.1016/j.biochi.2020.05.014. Epub 2020 Jun 16. PubMed |
Cerebral Dopamine Neurotrophic Factor Regulates Multiple Neuronal Subtypes and Behavior. Chen YC, Baronio D, Semenova S, Abdurakhmanova S, Panula P. J Neurosci. 2020 Aug 5;40(32):6146-6164. doi: 10.1523/JNEUROSCI.2636-19.2020. Epub 2020 Jul 6. PubMed |
PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation. Johansson JA, Marie KL, Lu Y, Brombin A, Santoriello C, Zeng Z, Zich J, Gautier P, von Kriegsheim A, Brunsdon H, Wheeler AP, Dreger M, Houston DR, Dooley CM, Sims AH, Busch-Nentwich EM, Zon LI, Illingworth RS, Patton EE. Dev Cell. 2020 Aug 10;54(3):317-332.e9. doi: 10.1016/j.devcel.2020.06.013. Epub 2020 Jul 10. PubMed |
The zebrafish histamine H3 receptor modulates aggression, neural activity and forebrain functional connectivity. Reichmann F, Rimmer N, Tilley CA, Dalla Vecchia E, Pinion J, Al Oustah A, Carreno Gutierrez H, Young AMJ, McDearmid JR, Winter MJ, Norton WHJ. Acta Physiol (Oxf). 2020 Dec;230(4):e13543. doi: 10.1111/apha.13543. Epub 2020 Aug 12. PubMed |
Investigation of Isoform Specific Functions of the V-ATPase a Subunit During Drosophila Wing Development. Mo D, Chen Y, Jiang N, Shen J, Zhang J. Front Genet. 2020 Jul 10;11:723. doi: 10.3389/fgene.2020.00723. eCollection 2020. PubMed |
ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression. Shi H, Tao T, Abraham BJ, Durbin AD, Zimmerman MW, Kadoch C, Look AT. Sci Adv. 2020 Jul 15;6(29):eaaz3440. doi: 10.1126/sciadv.aaz3440. eCollection 2020 Jul. PubMed |
Mouse models for V103I and I251L gain of function variants of the human MC4R display decreased adiposity but are not protected against a hypercaloric diet. Rojo D, McCarthy C, Raingo J, Rubinstein M. Mol Metab. 2020 Dec;42:101077. doi: 10.1016/j.molmet.2020.101077. Epub 2020 Sep 9. PubMed |
The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models. Klems A, van Rijssel J, Ramms AS, Wild R, Hammer J, Merkel M, Derenbach L, Preau L, Hinkel R, Suarez-Martinez I, Schulte-Merker S, Vidal R, Sauer S, Kivela R, Alitalo K, Kupatt C, van Buul JD, le Noble F. Nat Commun. 2020 Oct 21;11(1):5319. doi: 10.1038/s41467-020-19008-0. PubMed |
Targeting the Histone Methyltransferase Disruptor of Telomeric Silencing 1-Like Restricts Avian Leukosis Virus Subgroup J Replication by Restoring the Innate Immune Response in Chicken Macrophages. Chen S, Wang D, Liu Y, Zhao R, Wu T, Hu X, Pan Z, Cui H. Front Microbiol. 2020 Dec 8;11:603131. doi: 10.3389/fmicb.2020.603131. eCollection 2020. PubMed |
Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA. Choi H, Wang Z, Dean J. PLoS Genet. 2021 Apr 8;17(4):e1009485. doi: 10.1371/journal.pgen.1009485. eCollection 2021 Apr. PubMed |
A CRISPR/Cas9 zebrafish lamin A/C mutant model of muscular laminopathy. Nicolas HA, Hua K, Quigley H, Ivare J, Tesson F, Akimenko MA. Dev Dyn. 2022 Apr;251(4):645-661. doi: 10.1002/dvdy.427. Epub 2021 Oct 18. PubMed |
Hemoglobin in the blood acts as a chemosensory signal via the mouse vomeronasal system. Osakada T, Abe T, Itakura T, Mori H, Ishii KK, Eguchi R, Murata K, Saito K, Haga-Yamanaka S, Kimoto H, Yoshihara Y, Miyamichi K, Touhara K. Nat Commun. 2022 Feb 3;13(1):556. doi: 10.1038/s41467-022-28118-w. PubMed |
A hemimetabolous wing development suggests the wing origin from lateral tergum of a wingless ancestor. Ohde T, Mito T, Niimi T. Nat Commun. 2022 Feb 21;13(1):979. doi: 10.1038/s41467-022-28624-x. PubMed |
A Zebrafish Model for a Rare Genetic Disease Reveals a Conserved Role for FBXL3 in the Circadian Clock System. Confino S, Dor T, Tovin A, Wexler Y, Ben-Moshe Livne Z, Kolker M, Pisanty O, Park SK, Geyer N, Reiter J, Edvardson S, Mor-Shaked H, Elpeleg O, Vallone D, Appelbaum L, Foulkes NS, Gothilf Y. Int J Mol Sci. 2022 Feb 21;23(4). pii: ijms23042373. doi: 10.3390/ijms23042373. PubMed |
Genetic and Neurological Deficiencies in the Visual System of mct8 Mutant Zebrafish. Rozenblat R, Tovin A, Zada D, Lebenthal-Loinger I, Lerer-Goldshtein T, Appelbaum L. Int J Mol Sci. 2022 Feb 23;23(5). pii: ijms23052464. doi: 10.3390/ijms23052464. PubMed |
Oxytocin receptors influence the development and maintenance of social behavior in zebrafish (Danio rerio). Gemmer A, Mirkes K, Anneser L, Eilers T, Kibat C, Mathuru A, Ryu S, Schuman E. Sci Rep. 2022 Mar 12;12(1):4322. doi: 10.1038/s41598-022-07990-y. PubMed |
A single vomeronasal receptor promotes intermale aggression through dedicated hypothalamic neurons. Itakura T, Murata K, Miyamichi K, Ishii KK, Yoshihara Y, Touhara K. Neuron. 2022 Aug 3;110(15):2455-2469.e8. doi: 10.1016/j.neuron.2022.05.002. Epub 2022 Jun 1. PubMed |
Spatiotemporal Regulation of a Single Adaptively Evolving Trans-Regulatory Element Contributes to Spermatogenetic Expression Divergence in Drosophila. Huang Y, Shang R, Lu GA, Zeng W, Huang C, Zou C, Tang T. Mol Biol Evol. 2022 Jul 2;39(7). pii: 6605656. doi: 10.1093/molbev/msac127. PubMed |
Regulation of Nodal signaling propagation by receptor interactions and positive feedback. Preiss H, Kogler AC, Morsdorf D, Capek D, Soh GH, Rogers KW, Morales-Navarrete H, Almuedo-Castillo M, Muller P. Elife. 2022 Sep 23;11:e66397. doi: 10.7554/eLife.66397. PubMed |
Endothelial alpha globin is a nitrite reductase. Keller TCS 4th, Lechauve C, Keller AS, Broseghini-Filho GB, Butcher JT, Askew Page HR, Islam A, Tan ZY, DeLalio LJ, Brooks S, Sharma P, Hong K, Xu W, Padilha AS, Ruddiman CA, Best AK, Macal E, Kim-Shapiro DB, Christ G, Yan Z, Cortese-Krott MM, Ricart K, Patel R, Bender TP, Sonkusare SK, Weiss MJ, Ackerman H, Columbus L, Isakson BE. Nat Commun. 2022 Oct 27;13(1):6405. doi: 10.1038/s41467-022-34154-3. PubMed |
Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner. Mori M, Dai J, Miyahara H, Li Y, Kang X, Yoshimi K, Mashimo T, Higuchi K, Matsumoto K. Exp Anim. 2022 Nov 29. doi: 10.1538/expanim.22-0122. PubMed |
DIS3L2 ribonuclease degrades terminal-uridylated RNA to ensure oocyte maturation and female fertility. Wu D, Pedroza M, Chang J, Dean J. Nucleic Acids Res. 2023 Apr 24;51(7):3078-3093. doi: 10.1093/nar/gkad061. PubMed |
Generation of a homozygous GRIN2A gene knockout human embryonic stem cell line using CRISPR/Cas9 system. Luo X, Yang K, Jiang M, Chen T, Chi Y, Ma B, Lai L, Zou Q. Stem Cell Res. 2023 Jun;69:103121. doi: 10.1016/j.scr.2023.103121. Epub 2023 May 9. PubMed |
Generation of a homozygous RANGRF knockout hiPSC line by CRISPR/Cas9 system. Jiang M, Tang C, Luo X, Zhou X, Chen M, Chi Y, Lai L, Zou Q. Stem Cell Res. 2023 Jun 7;71:103136. doi: 10.1016/j.scr.2023.103136. PubMed |
G3'MTMD3 in the insect GABA receptor subunit, RDL, confers resistance to broflanilide and fluralaner. Zhang Y, Huang Q, Sheng C, Liu G, Zhang K, Jia Z, Tang T, Mao X, Jones AK, Han Z, Zhao C. PLoS Genet. 2023 Jun 29;19(6):e1010814. doi: 10.1371/journal.pgen.1010814. eCollection 2023 Jun. PubMed |
The endoribonuclease Arlr is required to maintain lipid homeostasis by downregulating lipolytic genes during aging. Sun X, Shen J, Perrimon N, Kong X, Wang D. Nat Commun. 2023 Oct 6;14(1):6254. doi: 10.1038/s41467-023-42042-7. PubMed |
Microbial ligand-independent regulation of lymphopoiesis by NOD1. Iwamura C, Ohnuki H, Flomerfelt FA, Zheng L, Carletti A, Wakashin H, Mikami Y, Brooks SR, Kanno Y, Gress RE, Tosato G, Nakayama T, O'Shea JJ, Sher A, Jankovic D. Nat Immunol. 2023 Dec;24(12):2080-2090. doi: 10.1038/s41590-023-01668-x. Epub 2023 Nov 13. PubMed |
Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes. Dereli I, Telychko V, Papanikos F, Raveendran K, Xu J, Boekhout M, Stanzione M, Neuditschko B, Imjeti NS, Selezneva E, Erbasi HT, Demir S, Giannattasio T, Gentzel M, Bondarieva A, Stevense M, Barchi M, Schnittger A, Weir JR, Herzog F, Keeney S, Toth A. bioRxiv [Preprint]. 2023 Nov 27:2023.11.27.568863. doi: 10.1101/2023.11.27.568863. PubMed |
Deficiency of heme oxygenase 1a causes detrimental effects on cardiac function. Wang H, Siren J, Perttunen S, Immonen K, Chen YC, Narumanchi S, Kosonen R, Paavola J, Laine M, Tikkanen I, Lakkisto P. J Cell Mol Med. 2024 Apr;28(7):e18243. doi: 10.1111/jcmm.18243. PubMed |
Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes. Dereli I, Telychko V, Papanikos F, Raveendran K, Xu J, Boekhout M, Stanzione M, Neuditschko B, Imjeti NS, Selezneva E, Tuncay H, Demir S, Giannattasio T, Gentzel M, Bondarieva A, Stevense M, Barchi M, Schnittger A, Weir JR, Herzog F, Keeney S, Toth A. Nat Commun. 2024 Apr 5;15(1):2941. doi: 10.1038/s41467-024-47020-1. PubMed |
A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification. Liu C, Nagashima H, Fernando N, Bass V, Gopalakrishnan J, Signorella S, Montgomery W, Lim AI, Harrison O, Reich L, Yao C, Sun HW, Brooks SR, Jiang K, Nagarajan V, Zhao Y, Jung S, Phillips R, Mikami Y, Lareau CA, Kanno Y, Jankovic D, Aryee MJ, Pekowska A, Belkaid Y, O'Shea J, Shih HY. Immunity. 2024 May 14;57(5):1005-1018.e7. doi: 10.1016/j.immuni.2024.04.007. Epub 2024 May 1. PubMed |
The evolutionary novelty of insect defensins: from bacterial killing to toxin neutralization. Gao B, Zhu S. Cell Mol Life Sci. 2024 May 23;81(1):230. doi: 10.1007/s00018-024-05273-5. PubMed |
If you have published an article using this material, please email us at [email protected] to have your article added to this page.