pCE-mp53DD Citations (46)
Originally described in: An Efficient Non-viral Method to Generate Integration-Free Human iPS Cells from Cord Blood and Peripheral Blood Cells.Okita K, Yamakawa T, Matsumura Y, Sato Y, Amano N, Watanabe A, Goshima N, Yamanaka S Stem Cells. 2012 Nov 29. doi: 10.1002/stem.1293. PubMed Journal
Articles Citing pCE-mp53DD
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Generation of human iPSCs from cells of fibroblastic and epithelial origin by means of the oriP/EBNA-1 episomal reprogramming system. Drozd AM, Walczak MP, Piaskowski S, Stoczynska-Fidelus E, Rieske P, Grzela DP. Stem Cell Res Ther. 2015 Jun 19;6:122. doi: 10.1186/s13287-015-0112-3. PubMed |
A Newly Defined and Xeno-Free Culture Medium Supports Every-Other-Day Medium Replacement in the Generation and Long-Term Cultivation of Human Pluripotent Stem Cells. Ahmadian Baghbaderani B, Tian X, Scotty Cadet J, Shah K, Walde A, Tran H, Kovarcik DP, Clarke D, Fellner T. PLoS One. 2016 Sep 8;11(9):e0161229. doi: 10.1371/journal.pone.0161229. eCollection 2016. PubMed |
Engineering a functional three-dimensional human cardiac tissue model for drug toxicity screening. Lu HF, Leong MF, Lim TC, Chua YP, Lim JK, Du C, Wan ACA. Biofabrication. 2017 May 11;9(2):025011. doi: 10.1088/1758-5090/aa6c3a. PubMed |
p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells. Ihry RJ, Worringer KA, Salick MR, Frias E, Ho D, Theriault K, Kommineni S, Chen J, Sondey M, Ye C, Randhawa R, Kulkarni T, Yang Z, McAllister G, Russ C, Reece-Hoyes J, Forrester W, Hoffman GR, Dolmetsch R, Kaykas A. Nat Med. 2018 Jul;24(7):939-946. doi: 10.1038/s41591-018-0050-6. Epub 2018 Jun 11. PubMed |
bFGF-mediated pluripotency maintenance in human induced pluripotent stem cells is associated with NRAS-MAPK signaling. Haghighi F, Dahlmann J, Nakhaei-Rad S, Lang A, Kutschka I, Zenker M, Kensah G, Piekorz RP, Ahmadian MR. Cell Commun Signal. 2018 Dec 5;16(1):96. doi: 10.1186/s12964-018-0307-1. PubMed |
Generation of induced pluripotent stem cell line, ICGi007-A, by reprogramming peripheral blood mononuclear cells from a patient with Huntington's disease. Grigor'eva EV, Malankhanova TB, Surumbayeva A, Minina JM, Morozov VV, Abramycheva NY, Illarioshkin SN, Malakhova AA, Zakian SM. Stem Cell Res. 2019 Jan;34:101382. doi: 10.1016/j.scr.2018.101382. Epub 2019 Jan 2. PubMed |
The Use of iPSC-Derived Cardiomyocytes and Optical Mapping for Erythromycin Arrhythmogenicity Testing. Podgurskaya AD, Tsvelaya VA, Slotvitsky MM, Dementyeva EV, Valetdinova KR, Agladze KI. Cardiovasc Toxicol. 2019 Jun 5. pii: 10.1007/s12012-019-09532-x. doi: 10.1007/s12012-019-09532-x. PubMed |
Efficient and flexible tagging of endogenous genes by homology-independent intron targeting.
Serebrenik YV, Sansbury SE, Kumar SS, Henao-Mejia J, Shalem O.
Genome Res. 2019 Aug;29(8):1322-1328. doi: 10.1101/gr.246413.118. Epub 2019 Jun 25.
PubMed
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CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons.
Tian R, Gachechiladze MA, Ludwig CH, Laurie MT, Hong JY, Nathaniel D, Prabhu AV, Fernandopulle MS, Patel R, Abshari M, Ward ME, Kampmann M.
Neuron. 2019 Aug 5. pii: S0896-6273(19)30640-3. doi: 10.1016/j.neuron.2019.07.014.
PubMed
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ToolBox: Live Imaging of intracellular organelle transport in induced pluripotent stem cell-derived neurons. Boecker CA, Olenick MA, Gallagher ER, Ward ME, Holzbaur ELF. Traffic. 2020 Jan;21(1):138-155. doi: 10.1111/tra.12701. Epub 2019 Nov 15. PubMed |
Highly efficient induced pluripotent stem cell reprogramming of cryopreserved lymphoblastoid cell lines. Kumar S, Curran JE, Espinosa EC, Glahn DC, Blangero J. J Biol Methods. 2020 Jan 8;7(1):e124. doi: 10.14440/jbm.2020.296. eCollection 2020. PubMed |
Mutation-Dependent Pathomechanisms Determine the Phenotype in the Bestrophinopathies. Nachtigal AL, Milenkovic A, Brandl C, Schulz HL, Duerr LMJ, Lang GE, Reiff C, Herrmann P, Kellner U, Weber BHF. Int J Mol Sci. 2020 Feb 26;21(5). pii: ijms21051597. doi: 10.3390/ijms21051597. PubMed |
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing. Artegiani B, Hendriks D, Beumer J, Kok R, Zheng X, Joore I, Chuva de Sousa Lopes S, van Zon J, Tans S, Clevers H. Nat Cell Biol. 2020 Mar;22(3):321-331. doi: 10.1038/s41556-020-0472-5. Epub 2020 Mar 2. PubMed |
Generation of induced pluripotent stem cell line ICGi018-A from peripheral blood mononuclear cells of a patient with Huntington's disease. Malakhova AA, Grigor'eva EV, Malankhanova TB, Pavlova SV, Valetdinova KR, Abramycheva NY, Vetchinova AS, Illarioshkin SN, Zakian SM. Stem Cell Res. 2020 Apr;44:101743. doi: 10.1016/j.scr.2020.101743. Epub 2020 Feb 21. PubMed |
Generation of a transgene-free iPSC line and genetically modified line from a facioscapulohumeral muscular dystrophy type 2 (FSHD2) patient with SMCHD1 p.Lys607Ter mutation. Sasaki-Honda M, Kagita A, Jonouchi T, Araki T, Hotta A, Sakurai H. Stem Cell Res. 2020 Jun 24;47:101884. doi: 10.1016/j.scr.2020.101884. PubMed |
Generation of a spinal muscular atrophy type III patient-specific induced pluripotent stem cell line ICGi003-A. Ovechkina VS, Maretina MA, Egorova AA, Baranov VS, Kiselev AV, Zakian SM, Valetdinova KR. Stem Cell Res. 2020 Oct;48:101938. doi: 10.1016/j.scr.2020.101938. Epub 2020 Aug 3. PubMed |
Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population. Malakhova AA, Grigor'eva EV, Pavlova SV, Malankhanova TB, Valetdinova KR, Vyatkin YV, Khabarova EA, Rzaev JA, Zakian SM, Medvedev SP. Stem Cell Res. 2020 Oct;48:101952. doi: 10.1016/j.scr.2020.101952. Epub 2020 Aug 8. PubMed |
Generation and characterization of human induced pluripotent stem cells lines from four patients diagnosed with schizophrenia and one healthy control. Stock R, Vogel S, Mau-Holzmann UA, Kriebel M, Wust R, Fallgatter AJ, Volkmer H. Stem Cell Res. 2020 Oct;48:101961. doi: 10.1016/j.scr.2020.101961. Epub 2020 Aug 27. PubMed |
Establishment of an induced pluripotent stem cell line (ICGi025-A) from fibroblasts of a patient with 46,XY,r(8)/45,XY,-8 mosaicism. Gridina MM, Nikitina TV, Orlova PA, Minina JM, Kashevarova AA, Yakovleva YS, Lopatkina ME, Vasilyev SA, Fedotov DA, Mikhailik LI, Nazarenko LP, Lebedev IN, Serov OL. Stem Cell Res. 2020 Dec;49:102024. doi: 10.1016/j.scr.2020.102024. Epub 2020 Oct 2. PubMed |
16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development. Roth JG, Muench KL, Asokan A, Mallett VM, Gai H, Verma Y, Weber S, Charlton C, Fowler JL, Loh KM, Dolmetsch RE, Palmer TD. Elife. 2020 Nov 10;9. pii: 58178. doi: 10.7554/eLife.58178. PubMed |
Establishment of an induced pluripotent stem cell line (ICGi026-A) from peripheral blood mononuclear cells of a patient with fragile X syndrome. Gridina MM, Orlova PA, Minina JM, Shitik EM, Lemskaya NA, Grishchenko IV, Dolskiy AA, Shorina AR, Maksimova YV, Yudkin DV, Serov OL. Stem Cell Res. 2020 Dec;49:102070. doi: 10.1016/j.scr.2020.102070. Epub 2020 Oct 29. PubMed |
Generation of iPSC line ICGi024-A from human skin fibroblasts of a patient with ring chromosome 18. Khabarova AA, Pristyazhnyuk IE, Orlova PA, Nikitina TV, Kashevarova AA, Lopatkina ME, Belyaeva EO, Sukhanova NN, Nazarenko LP, Lebedev IN, Serov OL. Stem Cell Res. 2020 Dec;49:102076. doi: 10.1016/j.scr.2020.102076. Epub 2020 Nov 3. PubMed |
Cyclophosphamide arrhythmogenicitytesting using human-induced pluripotent stem cell-derived cardiomyocytes. Podgurskaya AD, Slotvitsky MM, Tsvelaya VA, Frolova SR, Romanova SG, Balashov VA, Agladze KI. Sci Rep. 2021 Jan 27;11(1):2336. doi: 10.1038/s41598-020-79085-5. PubMed |
Generation of nonviral integration-free human iPS cell line KISCOi001-A from normal human fibroblasts, under defined xeno-free and feeder-free conditions. Inzunza J, Arias-Fuenzalida J, Segura-Aguilar J, Nalvarte I, Varshney M. Stem Cell Res. 2021 Mar;51:102193. doi: 10.1016/j.scr.2021.102193. Epub 2021 Jan 27. PubMed |
Generation of an induced pluripotent stem cell line, ICGi028-A, by reprogramming peripheral blood mononuclear cells of a patient suffering from hypertrophic cardiomyopathy and carrying a heterozygous p.E510Q mutation in HADHA. Dementyeva EV, Vyatkin YV, Chernyavsky AM, Zakian SM. Stem Cell Res. 2021 May;53:102348. doi: 10.1016/j.scr.2021.102348. Epub 2021 Apr 19. PubMed |
Generation of an induced pluripotent stem cell line, ICGi029-A, by reprogramming peripheral blood mononuclear cells of a patient suffering from hypertrophic cardiomyopathy and carrying a heterozygous p.N515del mutation in MYBPC3. Dementyeva EV, Pavlova SV, Chernyavsky AM, Zakian SM. Stem Cell Res. 2021 May;53:102344. doi: 10.1016/j.scr.2021.102344. Epub 2021 Apr 12. PubMed |
Non-viral derivation of a transgene-free induced pluripotent stem cell line from a male beagle dog. Yoshimatsu S, Edamura K, Yoshii Y, Iguchi A, Kondo H, Shibuya H, Sato T, Shiozawa S, Okano H. Stem Cell Res. 2021 May;53:102375. doi: 10.1016/j.scr.2021.102375. Epub 2021 Apr 29. PubMed |
Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients. de Souza AF, Bressan FF, Pieri NCG, Botigelli RC, Revay T, Haddad SK, Covas DT, Ramos ES, King WA, Meirelles FV. Cells. 2021 Nov 10;10(11). pii: cells10113099. doi: 10.3390/cells10113099. PubMed |
Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome. Gridina MM, Shitik EM, Lemskaya NA, Minina JM, Grishchenko IV, Dolskiy AA, Shorina AR, Maksimova YV, Yudkin DV. Stem Cell Res. 2021 Nov 29;57:102615. doi: 10.1016/j.scr.2021.102615. PubMed |
Generation of iPS cell line (ICGi040-A) from skin fibroblasts of a patient with ring small supernumerary marker chromosome 4. Gridina MM, Nurislamov AR, Minina JM, Lopatkina ME, Drozdov GV, Vasilyev SA, Minaycheva LI, Belyaeva EO, Nikitina TV, Kashevarova AA, Lebedev IN, Karamysheva TV, Rubtsov NB, Serov OL. Stem Cell Res. 2022 May;61:102740. doi: 10.1016/j.scr.2022.102740. Epub 2022 Feb 28. PubMed |
NF90-NF45 is essential for beta cell compensation under obesity-inducing metabolic stress through suppression of p53 signaling pathway. Lai S, Higuchi T, Tsuda M, Sugiyama Y, Morisawa K, Taniguchi T, Sakamoto S. Sci Rep. 2022 May 25;12(1):8837. doi: 10.1038/s41598-022-12600-y. PubMed |
Induced neural progenitor cells and iPS-neurons from major depressive disorder patients show altered bioenergetics and electrophysiological properties. Triebelhorn J, Cardon I, Kuffner K, Bader S, Jahner T, Meindl K, Rothhammer-Hampl T, Riemenschneider MJ, Drexler K, Berneburg M, Nothdurfter C, Manook A, Brochhausen C, Baghai TC, Hilbert S, Rupprecht R, Milenkovic VM, Wetzel CH. Mol Psychiatry. 2022 Jun 22. pii: 10.1038/s41380-022-01660-1. doi: 10.1038/s41380-022-01660-1. PubMed |
A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production. Genuth NR, Shi Z, Kunimoto K, Hung V, Xu AF, Kerr CH, Tiu GC, Oses-Prieto JA, Salomon-Shulman REA, Axelrod JD, Burlingame AL, Loh KM, Barna M. Nat Commun. 2022 Sep 19;13(1):5491. doi: 10.1038/s41467-022-33263-3. PubMed |
Transient inhibition of p53 enhances prime editing and cytosine base-editing efficiencies in human pluripotent stem cells.
Li M, Zhong A, Wu Y, Sidharta M, Beaury M, Zhao X, Studer L, Zhou T.
Nat Commun. 2022 Oct 27;13(1):6354. doi: 10.1038/s41467-022-34045-7.
PubMed
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Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction. Breitmeyer R, Vogel S, Heider J, Hartmann SM, Wust R, Keller AL, Binner A, Fitzgerald JC, Fallgatter AJ, Volkmer H. Commun Biol. 2023 Apr 29;6(1):472. doi: 10.1038/s42003-023-04852-9. PubMed |
A Mutant Methionyl-tRNA Synthetase-Based toolkit to assess induced-Mesenchymal Stromal Cell secretome in mixed-culture disease models. Burgess JD, Amerna D, Norton ES, Parsons TM, Iii RBP, Faroqi AH, Wszolek ZK, Cazares HG, Kanekiyo T, Delenclos M, McLean PJ. Res Sq. 2023 May 3:rs.3.rs-2838195. doi: 10.21203/rs.3.rs-2838195/v1. Preprint. PubMed |
Cas phosphorylation regulates focal adhesion assembly. Kumar S, Stainer A, Dubrulle J, Simpkins C, Cooper JA. Elife. 2023 Jul 25;12:e90234. doi: 10.7554/eLife.90234. PubMed |
Skeletal muscle cell protein dysregulation highlights the pathogenesis mechanism of myopathy-associated p97/VCP R155H mutations. Luzzi A, Wang F, Li S, Iacovino M, Chou TF. Front Neurol. 2023 Aug 3;14:1211635. doi: 10.3389/fneur.2023.1211635. eCollection 2023. PubMed |
Generation of a tyrosine hydroxylase-2A-Cre knockin non-human primate model by homology-directed-repair-biased CRISPR genome editing. Yoshimatsu S, Okahara J, Yoshie J, Igarashi Y, Nakajima R, Sanosaka T, Qian E, Sato T, Kobayashi H, Morimoto S, Kishi N, Pillis DM, Malik P, Noce T, Okano H. Cell Rep Methods. 2023 Sep 25;3(9):100590. doi: 10.1016/j.crmeth.2023.100590. Epub 2023 Sep 14. PubMed |
RAPIDASH: A tag-free enrichment of ribosome-associated proteins reveals compositional dynamics in embryonic tissues and stimulated macrophages. Susanto TT, Hung V, Levine AG, Kerr CH, Yoo Y, Chen Y, Oses-Prieto JA, Fromm L, Fujii K, Wernig M, Burlingame AL, Ruggero D, Barna M. bioRxiv [Preprint]. 2023 Dec 7:2023.12.07.570613. doi: 10.1101/2023.12.07.570613. PubMed |
IPSC-Derived Astrocytes Contribute to In Vitro Modeling of Parkinson's Disease Caused by the GBA1 N370S Mutation. Yarkova ES, Grigor'eva EV, Medvedev SP, Pavlova SV, Zakian SM, Malakhova AA. Int J Mol Sci. 2023 Dec 26;25(1):327. doi: 10.3390/ijms25010327. PubMed |
All three MutL complexes are required for repeat expansion in a human stem cell model of CAG-repeat expansion mediated glutaminase deficiency. Hayward B, Kumari D, Santra S, van Karnebeek CDM, van Kuilenburg ABP, Usdin K. bioRxiv [Preprint]. 2024 May 9:2023.12.26.573357. doi: 10.1101/2023.12.26.573357. PubMed |
Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment. Raabe FJ, Hausruckinger A, Gagliardi M, Ahmad R, Almeida V, Galinski S, Hoffmann A, Weigert L, Rummel CK, Murek V, Trastulla L, Jimenez-Barron L, Atella A, Maidl S, Menegaz D, Hauger B, Wagner EM, Gabellini N, Kauschat B, Riccardo S, Cesana M, Papiol S, Sportelli V, Rex-Haffner M, Stolte SJ, Wehr MC, Salcedo TO, Papazova I, Detera-Wadleigh S, McMahon FJ, Schmitt A, Falkai P, Hasan A, Cacchiarelli D, Dannlowski U, Nenadic I, Kircher T, Scheuss V, Eder M, Binder EB, Spengler D, Rossner MJ, Ziller MJ. bioRxiv [Preprint]. 2024 Jan 13:2024.01.09.574815. doi: 10.1101/2024.01.09.574815. PubMed |
Detection of ER Stress in iPSC-Derived Neurons Carrying the p.N370S Mutation in the GBA1 Gene. Yarkova ES, Grigor'eva EV, Medvedev SP, Tarasevich DA, Pavlova SV, Valetdinova KR, Minina JM, Zakian SM, Malakhova AA. Biomedicines. 2024 Mar 27;12(4):744. doi: 10.3390/biomedicines12040744. PubMed |
Human induced pluripotent stem cells (hiPSCs) derived cells reflect tissue specificity found in patients with Leigh syndrome French Canadian variant (LSFC). Gelinas R, Levesque C, Thompson Legault J, Rivard ME, Villeneuve L, Laprise C, Rioux JD. Front Genet. 2024 Apr 19;15:1375467. doi: 10.3389/fgene.2024.1375467. eCollection 2024. PubMed |
All three MutL complexes are required for repeat expansion in a human stem cell model of CAG-repeat expansion mediated glutaminase deficiency. Hayward B, Kumari D, Santra S, van Karnebeek CDM, van Kuilenburg ABP, Usdin K. Sci Rep. 2024 Jun 14;14(1):13772. doi: 10.1038/s41598-024-64480-z. PubMed |
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