pLEX_306 Citations (13)
Originally described in: Root Lab pLEX and pLIX Gateway backbonesUnpublished
Articles Citing pLEX_306
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Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth. Fontan L, Qiao Q, Hatcher JM, Casalena G, Us I, Teater M, Durant M, Du G, Xia M, Bilchuk N, Chennamadhavuni S, Palladino G, Inghirami G, Philippar U, Wu H, Scott DA, Gray NS, Melnick A. J Clin Invest. 2018 Oct 1;128(10):4397-4412. doi: 10.1172/JCI99436. Epub 2018 Jul 19. PubMed |
Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductase. Zheng Y, Ramsamooj S, Li Q, Johnson JL, Yaron TM, Sharra K, Cantley LC. Sci Rep. 2019 Mar 12;9(1):4190. doi: 10.1038/s41598-019-40950-7. PubMed |
Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma. Sato T, Yoo S, Kong R, Sinha A, Chandramani-Shivalingappa P, Patel A, Fridrikh M, Nagano O, Masuko T, Beasley MB, Powell CA, Zhu J, Watanabe H. Cancer Res. 2019 Dec 15;79(24):6084-6100. doi: 10.1158/0008-5472.CAN-19-2132. Epub 2019 Sep 24. PubMed |
Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas. Fortin J, Tian R, Zarrabi I, Hill G, Williams E, Sanchez-Duffhues G, Thorikay M, Ramachandran P, Siddaway R, Wong JF, Wu A, Apuzzo LN, Haight J, You-Ten A, Snow BE, Wakeham A, Goldhamer DJ, Schramek D, Bullock AN, Dijke PT, Hawkins C, Mak TW. Cancer Cell. 2020 Mar 16;37(3):308-323.e12. doi: 10.1016/j.ccell.2020.02.002. Epub 2020 Mar 5. PubMed |
Cell-Based Ligand Discovery for the ENL YEATS Domain. Asiaban JN, Milosevich N, Chen E, Bishop TR, Wang J, Zhang Y, Ackerman CJ, Hampton EN, Young TS, Hull MV, Cravatt BF, Erb MA. ACS Chem Biol. 2020 Apr 17;15(4):895-903. doi: 10.1021/acschembio.0c00124. Epub 2020 Mar 19. PubMed |
Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1. Brett JO, Arjona M, Ikeda M, Quarta M, de Morree A, Egner IM, Perandini LA, Ishak HD, Goshayeshi A, Benjamin DI, Both P, Rodriguez-Mateo C, Betley MJ, Wyss-Coray T, Rando TA. Nat Metab. 2020 Apr;2(4):307-317. doi: 10.1038/s42255-020-0190-0. Epub 2020 Apr 13. PubMed |
Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution. Leistico JR, Saini P, Futtner CR, Hejna M, Omura Y, Soni PN, Sandlesh P, Milad M, Wei JJ, Bulun S, Parker JB, Barish GD, Song JS, Chakravarti D. Cell Rep. 2021 Mar 30;34(13):108927. doi: 10.1016/j.celrep.2021.108927. PubMed |
Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML. Nicosia L, Boffo FL, Ceccacci E, Conforti F, Pallavicini I, Bedin F, Ravasio R, Massignani E, Somervaille TCP, Minucci S, Bonaldi T. Oncogene. 2022 Feb;41(6):878-894. doi: 10.1038/s41388-021-02123-7. Epub 2021 Dec 3. PubMed |
Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins. Mukherjee S, Maddalena M, Lu Y, Martinez S, Nataraj NB, Noronha A, Sinha S, Teng K, Cohen-Kaplan V, Ziv T, Arandkar S, Hassin O, Chatterjee R, Pirona AC, Shreberk-Shaked M, Gershoni A, Aylon Y, Elazar Z, Yarden Y, Schramek D, Oren M. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2119644119. doi: 10.1073/pnas.2119644119. Epub 2022 Apr 19. PubMed |
Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer. Kong R, Patel AS, Sato T, Jiang F, Yoo S, Bao L, Sinha A, Tian Y, Fridrikh M, Liu S, Feng J, He X, Jiang J, Ma Y, Grullon K, Yang D, Powell CA, Beasley MB, Zhu J, Snyder EL, Li S, Watanabe H. Am J Respir Crit Care Med. 2022 Dec 15;206(12):1480-1494. doi: 10.1164/rccm.202110-2358OC. PubMed |
Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition. Bishop TR, Subramanian C, Bilotta EM, Garnar-Wortzel L, Ramos AR, Zhang Y, Asiaban JN, Ott CJ, Rock CO, Erb MA. Nat Chem Biol. 2023 May 1. doi: 10.1038/s41589-023-01320-7. PubMed |
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability. Lu Y, Cho T, Mukherjee S, Suarez CF, Gonzalez-Foutel NS, Malik A, Martinez S, Dervovic D, Oh RH, Langille E, Al-Zahrani KN, Hoeg L, Lin ZY, Tsai R, Mbamalu G, Rotter V, Ashton-Prolla P, Moffat J, Chemes LB, Gingras AC, Oren M, Durocher D, Schramek D. Mol Syst Biol. 2024 Jun;20(6):719-740. doi: 10.1038/s44320-024-00032-x. Epub 2024 Apr 5. PubMed |
TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers. Damhofer H, Tatar T, Southgate B, Scarneo S, Agger K, Shlyueva D, Uhrbom L, Morrison GM, Hughes PF, Haystead T, Pollard SM, Helin K. Cell Death Dis. 2024 Apr 17;15(4):273. doi: 10.1038/s41419-024-06654-1. PubMed |
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