Addgene: EGFP-alphasynuclein-A53T Citations

EGFP-alphasynuclein-A53T Citations (29)

Originally described in: Alpha-synuclein overexpression promotes aggregation of mutant huntingtin.
Furlong RA, Narain Y, Rankin J, Wyttenbach A, Rubinsztein DC Biochem J. 2000 Mar 15;346 Pt 3:577-81. PubMed Journal

Articles Citing EGFP-alphasynuclein-A53T

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The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons. Russo T, Kolisnyk B, B S A, Plessis-Belair J, Kim TW, Martin J, Ni J, Pearson JA, Park EJ, Sher RB, Studer L, Riessland M. Aging Cell. 2024 Apr;23(4):e14077. doi: 10.1111/acel.14077. Epub 2024 Feb 1. PubMed
Neuroprotective effects of osmotin in Parkinson's disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways. Park JS, Choe K, Lee HJ, Park TJ, Kim MO. J Biomed Sci. 2023 Aug 11;30(1):66. doi: 10.1186/s12929-023-00961-z. PubMed
The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons. Russo T, Kolisnyk B, Bs A, Kim TW, Martin J, Plessis-Belair J, Ni J, Pearson JA, Park EJ, Sher RB, Studer L, Riessland M. bioRxiv. 2023 Jul 21:2023.07.19.549710. doi: 10.1101/2023.07.19.549710. Preprint. PubMed
O-Cyclic Phytosphingosine-1-Phosphate Protects against Motor Dysfunctions and Glial Cell Mediated Neuroinflammation in the Parkinson's Disease Mouse Models. Lee HJ, Choe K, Park JS, Khan A, Kim MW, Park TJ, Kim MO. Antioxidants (Basel). 2022 Oct 26;11(11):2107. doi: 10.3390/antiox11112107. PubMed
Retrograde Axonal Autophagy and Endocytic Pathways Are Parallel and Separate in Neurons. Kulkarni VV, Stempel MH, Anand A, Sidibe DK, Maday S. J Neurosci. 2022 Nov 9;42(45):8524-8541. doi: 10.1523/JNEUROSCI.1292-22.2022. Epub 2022 Sep 27. PubMed
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance. Wrobel L, Hill SM, Djajadikerta A, Fernandez-Estevez M, Karabiyik C, Ashkenazi A, Barratt VJ, Stamatakou E, Gunnarsson A, Rasmusson T, Miele EW, Beaton N, Bruderer R, Feng Y, Reiter L, Castaldi MP, Jarvis R, Tan K, Burli RW, Rubinsztein DC. Nat Commun. 2022 Jul 16;13(1):4146. doi: 10.1038/s41467-022-31905-0. PubMed
Reduction of phosphorylated alpha-synuclein through downregulation of casein kinase 2alpha alleviates dopaminergic-neuronal function. Potdar C, Kaushal A, Raj A, Mallick R, Datta I. Biochem Biophys Res Commun. 2022 Jul 30;615:43-48. doi: 10.1016/j.bbrc.2022.05.023. Epub 2022 May 11. PubMed
Sequestration of TDP-43(216-414) Aggregates by Cytoplasmic Expression of the proSAAS Chaperone. Peinado JR, Chaplot K, Jarvela TS, Barbieri EM, Shorter J, Lindberg I. ACS Chem Neurosci. 2022 Jun 1;13(11):1651-1665. doi: 10.1021/acschemneuro.2c00156. Epub 2022 May 12. PubMed Associated Plasmids Flag-mproSAAS (27 kDa)
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy. Qiu WQ, Ai W, Zhu FD, Zhang Y, Guo MS, Law BY, Wu JM, Wong VK, Tang Y, Yu L, Chen Q, Yu CL, Liu J, Qin DL, Zhou XG, Wu AG. Free Radic Biol Med. 2022 Feb 1;179:76-94. doi: 10.1016/j.freeradbiomed.2021.12.263. Epub 2021 Dec 20. PubMed
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease. Chen J, Mao K, Yu H, Wen Y, She H, Zhang H, Liu L, Li M, Li W, Zou F. J Neuroinflammation. 2021 Dec 20;18(1):295. doi: 10.1186/s12974-021-02349-y. PubMed

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