pLKO.1-sh-hSOX9-1 Citations (11)

Originally described in: Slug and Sox9 cooperatively determine the mammary stem cell state.
Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zurrer-Hardi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA Cell. 2012 Mar 2;148(5):1015-28. PubMed Journal

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Articles Citing pLKO.1-sh-hSOX9-1

Articles
SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma. Luanpitpong S, Li J, Manke A, Brundage K, Ellis E, McLaughlin SL, Angsutararux P, Chanthra N, Voronkova M, Chen YC, Wang L, Chanvorachote P, Pei M, Issaragrisil S, Rojanasakul Y. Oncogene. 2015 Sep 21. doi: 10.1038/onc.2015.351. PubMed
Iron induces cancer stem cells and aggressive phenotypes in human lung cancer cells. Chanvorachote P, Luanpitpong S. Am J Physiol Cell Physiol. 2016 May 1;310(9):C728-39. doi: 10.1152/ajpcell.00322.2015. Epub 2016 Feb 24. PubMed
SOX9 Elevation Acts with Canonical WNT Signaling to Drive Gastric Cancer Progression. Santos JC, Carrasco-Garcia E, Garcia-Puga M, Aldaz P, Montes M, Fernandez-Reyes M, de Oliveira CC, Lawrie CH, Arauzo-Bravo MJ, Ribeiro ML, Matheu A. Cancer Res. 2016 Nov 15;76(22):6735-6746. doi: 10.1158/0008-5472.CAN-16-1120. Epub 2016 Aug 28. PubMed
SOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin. Carrasco-Garcia E, Lopez L, Aldaz P, Arevalo S, Aldaregia J, Egana L, Bujanda L, Cheung M, Sampron N, Garcia I, Matheu A. Sci Rep. 2016 Aug 30;6:32350. doi: 10.1038/srep32350. PubMed
Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition. Mateo F, Arenas EJ, Aguilar H, Serra-Musach J, de Garibay GR, Boni J, Maicas M, Du S, Iorio F, Herranz-Ors C, Islam A, Prado X, Llorente A, Petit A, Vidal A, Catala I, Soler T, Venturas G, Rojo-Sebastian A, Serra H, Cuadras D, Blanco I, Lozano J, Canals F, Sieuwerts AM, de Weerd V, Look MP, Puertas S, Garcia N, Perkins AS, Bonifaci N, Skowron M, Gomez-Baldo L, Hernandez V, Martinez-Aranda A, Martinez-Iniesta M, Serrat X, Ceron J, Brunet J, Barretina MP, Gil M, Falo C, Fernandez A, Morilla I, Pernas S, Pla MJ, Andreu X, Segui MA, Ballester R, Castella E, Nellist M, Morales S, Valls J, Velasco A, Matias-Guiu X, Figueras A, Sanchez-Mut JV, Sanchez-Cespedes M, Cordero A, Gomez-Miragaya J, Palomero L, Gomez A, Gajewski TF, Cohen EE, Jesiotr M, Bodnar L, Quintela-Fandino M, Lopez-Bigas N, Valdes-Mas R, Puente XS, Vinals F, Casanovas O, Graupera M, Hernandez-Losa J, Ramon Y Cajal S, Garcia-Alonso L, Saez-Rodriguez J, Esteller M, Sierra A, Martin-Martin N, Matheu A, Carracedo A, Gonzalez-Suarez E, Nanjundan M, Cortes J, Lazaro C, Odero MD, Martens JW, Moreno-Bueno G, Barcellos-Hoff MH, Villanueva A, Gomis RR, Pujana MA. Oncogene. 2016 Dec 19. doi: 10.1038/onc.2016.427. PubMed
SOX9 promotes tumor progression through the axis BMI1-p21(CIP). Aldaz P, Otaegi-Ugartemendia M, Saenz-Antonanzas A, Garcia-Puga M, Moreno-Valladares M, Flores JM, Gerovska D, Arauzo-Bravo MJ, Sampron N, Matheu A, Carrasco-Garcia E. Sci Rep. 2020 Jan 15;10(1):357. doi: 10.1038/s41598-019-57047-w. PubMed
Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells. Lopez-Valero I, Davila D, Gonzalez-Martinez J, Salvador-Tormo N, Lorente M, Saiz-Ladera C, Torres S, Gabicagogeascoa E, Hernandez-Tiedra S, Garcia-Taboada E, Mendiburu-Elicabe M, Rodriguez-Fornes F, Sanchez-Dominguez R, Segovia JC, Sanchez-Gomez P, Matheu A, Sepulveda JM, Velasco G. Theranostics. 2020 Apr 6;10(11):5120-5136. doi: 10.7150/thno.41450. eCollection 2020. PubMed
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons. Li A, Cartwright S, Yu A, Ho SM, Schrode N, Deans PJM, Matos MR, Garcia MF, Townsley KG, Zhang B, Brennand KJ. STAR Protoc. 2021 Jun 3;2(2):100580. doi: 10.1016/j.xpro.2021.100580. eCollection 2021 Jun 18. PubMed
SOX9 Triggers Different Epithelial to Mesenchymal Transition States to Promote Pancreatic Cancer Progression. Carrasco-Garcia E, Lopez L, Moncho-Amor V, Carazo F, Aldaz P, Collado M, Bell D, Gaafar A, Karamitopoulou E, Tzankov A, Hidalgo M, Rubio A, Serrano M, Lawrie CH, Lovell-Badge R, Matheu A. Cancers (Basel). 2022 Feb 12;14(4). pii: cancers14040916. doi: 10.3390/cancers14040916. PubMed
High SOX9 Maintains Glioma Stem Cell Activity through a Regulatory Loop Involving STAT3 and PML. Aldaz P, Martin-Martin N, Saenz-Antonanzas A, Carrasco-Garcia E, Alvarez-Satta M, Elua-Pinin A, Pollard SM, Lawrie CH, Moreno-Valladares M, Sampron N, Hench J, Lovell-Badge R, Carracedo A, Matheu A. Int J Mol Sci. 2022 Apr 19;23(9). pii: ijms23094511. doi: 10.3390/ijms23094511. PubMed
Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory. Michelatti D, Beyes S, Bernardis C, Negri ML, Morelli L, Bediaga NG, Poli V, Fagnocchi L, Lago S, D'Annunzio S, Cona N, Gaspardo I, Bianchi A, Jovetic J, Gianesello M, Turdo A, D'Accardo C, Gaggianesi M, Dori M, Forcato M, Crispatzu G, Rada-Iglesias A, Sosa MS, Timmers HTM, Bicciato S, Todaro M, Tiberi L, Zippo A. Nat Commun. 2024 Mar 19;15(1):2198. doi: 10.1038/s41467-024-46524-0. PubMed

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