pCEFL3xHAmGli2 Citations (3)
Originally described in: Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus.Kim J, Kato M, Beachy PA Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21666-71. Epub 2009 Dec 8. PubMed Journal
Articles Citing pCEFL3xHAmGli2
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Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics. Moore BS, Stepanchick AN, Tewson PH, Hartle CM, Zhang J, Quinn AM, Hughes TE, Mirshahi T. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13069-13074. Epub 2016 Oct 31. PubMed |
Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway. Liu Y, Kim HG, Dong E, Dong C, Huang M, Liu Y, Liangpunsakul S, Dong XC. Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1;1865(10):2685-2693. doi: 10.1016/j.bbadis.2019.07.011. Epub 2019 Jul 24. PubMed |
Prostaglandin E1 Inhibits GLI2 Amplification-Associated Activation of the Hedgehog Pathway and Drug Refractory Tumor Growth. Wu F, Zhang C, Zhao C, Wu H, Teng Z, Jiang T, Wang Y. Cancer Res. 2020 Jul 1;80(13):2818-2832. doi: 10.1158/0008-5472.CAN-19-2052. Epub 2020 May 5. PubMed |
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