pCMV-Tag2B EDD Citations (12)

Originally described in: EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response.
Henderson MJ, Russell AJ, Hird S, Munoz M, Clancy JL, Lehrbach GM, Calanni ST, Jans DA, Sutherland RL, Watts CK J Biol Chem. 2002 Jul 19;277(29):26468-78. Epub 2002 May 13. PubMed Journal

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Articles Citing pCMV-Tag2B EDD

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Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages. Song M, Yeku OO, Rafiq S, Purdon T, Dong X, Zhu L, Zhang T, Wang H, Yu Z, Mai J, Shen H, Nixon B, Li M, Brentjens RJ, Ma X. Nat Commun. 2020 Dec 8;11(1):6298. doi: 10.1038/s41467-020-20140-0. PubMed
The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease. Dhingani N, Guo C, Pan J, Li Q, Warner N, Jardine S, Leung G, Kotlarz D, Gonzaga-Jauregui C, Klein C, Snapper SB, Navas-Lopez VM, Muise AM. Sci Rep. 2020 Oct 29;10(1):18648. doi: 10.1038/s41598-020-73482-6. PubMed
Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response. Song M, Wang C, Wang H, Zhang T, Li J, Benezra R, Chouchane L, Sun YH, Cui XG, Ma X. Oncoimmunology. 2020 Apr 14;9(1):1746148. doi: 10.1080/2162402X.2020.1746148. eCollection 2020. PubMed
A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins. Rigogliuso G, Biniossek ML, Goodier JL, Mayer B, Pereira GC, Schilling O, Meese E, Mayer J. Mob DNA. 2019 Aug 22;10:36. doi: 10.1186/s13100-019-0178-z. eCollection 2019. PubMed
Prolactin-inducible EDD E3 ubiquitin ligase promotes TORC1 signalling, anti-apoptotic protein expression, and drug resistance in breast cancer cells. MacDonald TM, Thomas LN, Daze E, Marignani P, Barnes PJ, Too CK. Am J Cancer Res. 2019 Jul 1;9(7):1484-1503. eCollection 2019. PubMed
Stability of the HTLV-1 Antisense-Derived Protein, HBZ, Is Regulated by the E3 Ubiquitin-Protein Ligase, UBR5. Panfil AR, Al-Saleem J, Howard CM, Shkriabai N, Kvaratskhelia M, Green PL. Front Microbiol. 2018 Jan 30;9:80. doi: 10.3389/fmicb.2018.00080. eCollection 2018. PubMed
E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer. Liao L, Song M, Li X, Tang L, Zhang T, Zhang L, Pan Y, Chouchane L, Ma X. Cancer Res. 2017 Apr 15;77(8):2090-2101. doi: 10.1158/0008-5472.CAN-16-2409. Epub 2017 Mar 22. PubMed
Cep78 controls centrosome homeostasis by inhibiting EDD-DYRK2-DDB1(Vpr)(BP). Hossain D, Javadi Esfehani Y, Das A, Tsang WY. EMBO Rep. 2017 Apr;18(4):632-644. doi: 10.15252/embr.201642377. Epub 2017 Feb 27. PubMed
Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin. Matsuura K, Huang NJ, Cocce K, Zhang L, Kornbluth S. Oncogene. 2016 Oct 10. doi: 10.1038/onc.2016.336. PubMed
E3 ligase EDD1/UBR5 is utilized by the HPV E6 oncogene to destabilize tumor suppressor TIP60. Subbaiah VK, Zhang Y, Rajagopalan D, Abdullah LN, Yeo-Teh NS, Tomaic V, Banks L, Myers MP, Chow EK, Jha S. Oncogene. 2015 Aug 3. doi: 10.1038/onc.2015.268. PubMed

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