pT7-7 asyn WT Citations (25)
Originally described in: Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein.Paleologou KE, Schmid AW, Rospigliosi CC, Kim HY, Lamberto GR, Fredenburg RA, Lansbury PT Jr, Fernandez CO, Eliezer D, Zweckstetter M, Lashuel HA J Biol Chem. 2008 Jun 13;283(24):16895-905. Epub 2008 Mar 14. PubMed Journal
Articles Citing pT7-7 asyn WT
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Role of Sporadic Parkinson Disease Associated Mutations A18T and A29S in Enhanced alpha-Synuclein Fibrillation and Cytotoxicity. Kumar S, Jangir DK, Kumar R, Kumari M, Bhavesh NS, Maiti TK. ACS Chem Neurosci. 2018 Feb 21;9(2):230-240. doi: 10.1021/acschemneuro.6b00430. Epub 2017 Sep 6. PubMed |
On the efficient bio-incorporation of 5-hydroxy-tryptophan in recombinant proteins expressed in Escherichia coli with T7 RNA polymerase-based vectors. Oliveira-Souza WP, Bronze F, Broos J, Marcondes MFM, Oliveira V. Biochem Biophys Res Commun. 2017 Oct 21;492(3):343-348. doi: 10.1016/j.bbrc.2017.08.111. Epub 2017 Aug 30. PubMed |
alpha-Synuclein Aggregation Monitored by Thioflavin T Fluorescence Assay. Wordehoff MM, Hoyer W. Bio Protoc. 2018 Jul 20;8(14). doi: 10.21769/BioProtoc.2941. PubMed |
Probing Alpha-Synuclein Conformations by Electron Paramagnetic Resonance (EPR) Spectroscopy. Cattani J, Braun T, Drescher M. Methods Mol Biol. 2019;1948:247-260. doi: 10.1007/978-1-4939-9124-2_19. PubMed |
Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme. Cliffe R, Sang JC, Kundel F, Finley D, Klenerman D, Ye Y. Cell Rep. 2019 Feb 19;26(8):2140-2149.e3. doi: 10.1016/j.celrep.2019.01.096. PubMed |
Thymoquinone prevents neurodegeneration against MPTP in vivo and modulates alpha-synuclein aggregation in vitro. Ardah MT, Merghani MM, Haque ME. Neurochem Int. 2019 Sep;128:115-126. doi: 10.1016/j.neuint.2019.04.014. Epub 2019 Apr 24. PubMed |
Alpha-Synuclein Is a Target of Fic-Mediated Adenylylation/AMPylation: Possible Implications for Parkinson's Disease. Sanyal A, Dutta S, Camara A, Chandran A, Koller A, Watson BG, Sengupta R, Ysselstein D, Montenegro P, Cannon J, Rochet JC, Mattoo S. J Mol Biol. 2019 May 31;431(12):2266-2282. doi: 10.1016/j.jmb.2019.04.026. Epub 2019 Apr 27. PubMed |
alpha-Synuclein chaperone suppresses nucleation and amyloidogenesis of prion protein. Shirasaka M, Kuwata K, Honda R. Biochem Biophys Res Commun. 2020 Jan 1;521(1):259-264. doi: 10.1016/j.bbrc.2019.10.120. Epub 2019 Oct 18. PubMed |
Partially oxidized DJ-1 inhibits alpha-synuclein nucleation and remodels mature alpha-synuclein fibrils in vitro. Kumar R, Kumar S, Hanpude P, Singh AK, Johari T, Majumder S, Maiti TK. Commun Biol. 2019 Oct 30;2:395. doi: 10.1038/s42003-019-0644-7. eCollection 2019. PubMed |
Real-Time 3D Imaging and Inhibition Analysis of Various Amyloid Aggregations Using Quantum Dots. Lin X, Galaqin N, Tainaka R, Shimamori K, Kuragano M, Noguchi TQP, Tokuraku K. Int J Mol Sci. 2020 Mar 13;21(6). pii: ijms21061978. doi: 10.3390/ijms21061978. PubMed |
Real-time 3D single molecule tracking. Hou S, Exell J, Welsher K. Nat Commun. 2020 Jul 17;11(1):3607. doi: 10.1038/s41467-020-17444-6. PubMed |
Dose-related biphasic effect of the Parkinson's disease neurotoxin MPTP, on the spread, accumulation, and toxicity of alpha-synuclein. Merghani MM, Ardah MT, Al Shamsi M, Kitada T, Haque ME. Neurotoxicology. 2021 May;84:41-52. doi: 10.1016/j.neuro.2021.02.001. Epub 2021 Feb 4. PubMed |
Protein in-cell NMR spectroscopy at 1.2 GHz. Luchinat E, Barbieri L, Cremonini M, Banci L. J Biomol NMR. 2021 Mar;75(2-3):97-107. doi: 10.1007/s10858-021-00358-w. Epub 2021 Feb 12. PubMed |
Identification of Natural Products as Potential Pharmacological Chaperones for Protein Misfolding Diseases. Sharma R, Srivastava T, Pandey AR, Mishra T, Gupta B, Reddy SS, Singh SP, Narender T, Tripathi A, Chandramouli B, Sashidhara KV, Priya S, Kumar N. ChemMedChem. 2021 Jul 6;16(13):2146-2156. doi: 10.1002/cmdc.202100147. Epub 2021 May 4. PubMed |
In situ architecture of neuronal alpha-Synuclein inclusions. Trinkaus VA, Riera-Tur I, Martinez-Sanchez A, Bauerlein FJB, Guo Q, Arzberger T, Baumeister W, Dudanova I, Hipp MS, Hartl FU, Fernandez-Busnadiego R. Nat Commun. 2021 Apr 14;12(1):2110. doi: 10.1038/s41467-021-22108-0. PubMed |
Ellagic Acid Inhibits alpha-Synuclein Aggregation at Multiple Stages and Reduces Its Cytotoxicity. Kumar S, Kumar R, Kumari M, Kumari R, Saha S, Bhavesh NS, Maiti TK. ACS Chem Neurosci. 2021 Jun 2;12(11):1919-1930. doi: 10.1021/acschemneuro.1c00001. Epub 2021 May 20. PubMed |
Molecular insights into alpha-synuclein interaction with individual human core histones, linker histone, and dsDNA. Jos S, Gogoi H, Prasad TK, Hurakadli MA, Kamariah N, Padmanabhan B, Padavattan S. Protein Sci. 2021 Oct;30(10):2121-2131. doi: 10.1002/pro.4167. Epub 2021 Aug 19. PubMed |
Ellagic Acid Prevents alpha-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated alpha-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy. Ardah MT, Eid N, Kitada T, Haque ME. Int J Mol Sci. 2021 Dec 13;22(24). pii: ijms222413398. doi: 10.3390/ijms222413398. PubMed |
Single Molecule Fingerprinting Reveals Different Amplification Properties of alpha-Synuclein Oligomers and Preformed Fibrils in Seeding Assay. Lau D, Magnan C, Hill K, Cooper A, Gambin Y, Sierecki E. ACS Chem Neurosci. 2022 Apr 6;13(7):883-896. doi: 10.1021/acschemneuro.1c00553. Epub 2022 Mar 14. PubMed |
Lipids and EGCG Affect alpha-Synuclein Association and Disruption of Nanodiscs. Sanders HM, Kostelic MM, Zak CK, Marty MT. Biochemistry. 2022 Jun 7;61(11):1014-1021. doi: 10.1021/acs.biochem.2c00160. Epub 2022 May 26. PubMed |
Detection of neuron-derived pathological alpha-synuclein in blood. Kluge A, Bunk J, Schaeffer E, Drobny A, Xiang W, Knacke H, Bub S, Luckstadt W, Arnold P, Lucius R, Berg D, Zunke F. Brain. 2022 Sep 14;145(9):3058-3071. doi: 10.1093/brain/awac115. PubMed |
Translocation of Distinct Alpha Synuclein Species from the Nucleus to Neuronal Processes during Neuronal Differentiation. Pieger K, Schmitt V, Gauer C, Giessl N, Prots I, Winner B, Winkler J, Brandstatter JH, Xiang W. Biomolecules. 2022 Aug 12;12(8):1108. doi: 10.3390/biom12081108. PubMed |
Toward high-throughput oligomer detection and classification for early-stage aggregation of amyloidogenic protein. Tahirbegi B, Magness AJ, Piersimoni ME, Teng X, Hooper J, Guo Y, Knopfel T, Willison KR, Klug DR, Ying L. Front Chem. 2022 Aug 30;10:967882. doi: 10.3389/fchem.2022.967882. eCollection 2022. PubMed |
Kinetic parameters of alpha-synuclein seed amplification assay correlate with cognitive impairment in patients with Lewy body disorders. Brauer S, Rossi M, Sajapin J, Henle T, Gasser T, Parchi P, Brockmann K, Falkenburger BH. Acta Neuropathol Commun. 2023 Oct 9;11(1):162. doi: 10.1186/s40478-023-01653-3. PubMed |
Activation and Purification of ss-Glucocerebrosidase by Exploiting its Transporter LIMP-2 - Implications for Novel Treatment Strategies in Gaucher's and Parkinson's Disease. Dobert JP, Bub S, Machtel R, Januliene D, Steger L, Regensburger M, Wilfling S, Chen JX, Dejung M, Plotz S, Hehr U, Moeller A, Arnold P, Zunke F. Adv Sci (Weinh). 2024 Jul;11(25):e2401641. doi: 10.1002/advs.202401641. Epub 2024 Apr 26. PubMed |
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