LAMP1-mGFP Citations (79)
Originally described in: Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.Falcon-Perez JM, Nazarian R, Sabatti C, Dell'Angelica EC J Cell Sci. 2005 Nov 15;118(Pt 22):5243-55. Epub 2005 Oct 25. PubMed Journal
Articles Citing LAMP1-mGFP
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Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway. Das U, Wang L, Ganguly A, Saikia JM, Wagner SL, Koo EH, Roy S. Nat Neurosci. 2016 Jan;19(1):55-64. doi: 10.1038/nn.4188. Epub 2015 Dec 7. PubMed |
Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation. Brennan TV, Lin L, Brandstadter JD, Rendell VR, Dredge K, Huang X, Yang Y. J Clin Invest. 2016 Jan;126(1):207-19. doi: 10.1172/JCI76566. Epub 2015 Dec 7. PubMed |
Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy. Baulies A, Ribas V, Nunez S, Torres S, Alarcon-Vila C, Martinez L, Suda J, Ybanez MD, Kaplowitz N, Garcia-Ruiz C, Fernandez-Checa JC. Sci Rep. 2015 Dec 11;5:18017. doi: 10.1038/srep18017. PubMed |
Imaging organelle transport in primary hippocampal neurons treated with amyloid-beta oligomers. Gan KJ, Silverman MA. Methods Cell Biol. 2016;131:425-51. doi: 10.1016/bs.mcb.2015.06.012. Epub 2015 Sep 2. PubMed |
Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation. Percher A, Ramakrishnan S, Thinon E, Yuan X, Yount JS, Hang HC. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4302-7. doi: 10.1073/pnas.1602244113. Epub 2016 Apr 4. PubMed |
A melanosomal two-pore sodium channel regulates pigmentation. Bellono NW, Escobar IE, Oancea E. Sci Rep. 2016 May 27;6:26570. doi: 10.1038/srep26570. PubMed |
Role of LAMP1 Binding and pH Sensing by the Spike Complex of Lassa Virus. Cohen-Dvashi H, Israeli H, Shani O, Katz A, Diskin R. J Virol. 2016 Oct 28;90(22):10329-10338. Print 2016 Nov 15. PubMed |
Mouse RAGE Variant 4 Is a Dominant Membrane Receptor that Does Not Shed to Generate Soluble RAGE. Peng Y, Horwitz N, Lakatta EG, Lin L. PLoS One. 2016 Sep 21;11(9):e0153657. doi: 10.1371/journal.pone.0153657. eCollection 2016. PubMed |
BECN1/Beclin 1 sorts cell-surface APP/amyloid beta precursor protein for lysosomal degradation. Swaminathan G, Zhu W, Plowey ED. Autophagy. 2016 Dec;12(12):2404-2419. Epub 2016 Oct 7. PubMed |
Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B12-trafficking proteins ABCD4 and LMBD1. Fettelschoss V, Burda P, Sagne C, Coelho D, De Laet C, Lutz S, Suormala T, Fowler B, Pietrancosta N, Gasnier B, Bornhauser B, Froese DS, Baumgartner MR. J Biol Chem. 2017 Jul 14;292(28):11980-11991. doi: 10.1074/jbc.M117.784819. Epub 2017 Jun 1. PubMed |
Intracellular trafficking of particles inside endosomal vesicles is regulated by particle size. Aoyama M, Yoshioka Y, Arai Y, Hirai H, Ishimoto R, Nagano K, Higashisaka K, Nagai T, Tsutsumi Y. J Control Release. 2017 Aug 28;260:183-193. doi: 10.1016/j.jconrel.2017.06.007. Epub 2017 Jun 13. PubMed |
PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes. Bissig C, Hurbain I, Raposo G, van Niel G. Traffic. 2017 Nov;18(11):747-757. doi: 10.1111/tra.12525. PubMed |
New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision.
Wood LA, Larocque G, Clarke NI, Sarkar S, Royle SJ.
J Cell Biol. 2017 Sep 27. pii: jcb.201702188. doi: 10.1083/jcb.201702188.
PubMed
Associated Plasmids |
The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Gaidt MM, Ebert TS, Chauhan D, Ramshorn K, Pinci F, Zuber S, O'Duill F, Schmid-Burgk JL, Hoss F, Buhmann R, Wittmann G, Latz E, Subklewe M, Hornung V. Cell. 2017 Nov 16;171(5):1110-1124.e18. doi: 10.1016/j.cell.2017.09.039. Epub 2017 Oct 12. PubMed |
The trafficking protein, EHD2, positively regulates cardiac sarcolemmal KATP channel surface expression: role in cardioprotection. Yang HQ, Jana K, Rindler MJ, Coetzee WA. FASEB J. 2018 Mar;32(3):1613-1625. doi: 10.1096/fj.201700027R. Epub 2018 Jan 3. PubMed |
Ferroquine, the next generation antimalarial drug, has antitumor activity. Kondratskyi A, Kondratska K, Vanden Abeele F, Gordienko D, Dubois C, Toillon RA, Slomianny C, Lemiere S, Delcourt P, Dewailly E, Skryma R, Biot C, Prevarskaya N. Sci Rep. 2017 Nov 21;7(1):15896. doi: 10.1038/s41598-017-16154-2. PubMed |
Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis. Wong YC, Ysselstein D, Krainc D. Nature. 2018 Feb 15;554(7692):382-386. doi: 10.1038/nature25486. Epub 2018 Jan 24. PubMed |
A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3. Fu R, Deng Q, Zhang H, Hu X, Li Y, Liu Y, Hu J, Luo Q, Zhang Y, Jiang X, Li L, Yang C, Gao N. Cell Death Dis. 2018 Feb 14;9(2):243. doi: 10.1038/s41419-018-0276-8. PubMed |
HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System. Shi J, Xiong R, Zhou T, Su P, Zhang X, Qiu X, Li H, Li S, Yu C, Wang B, Ding C, Smithgall TE, Zheng YH. J Virol. 2018 May 14;92(11). pii: JVI.00196-18. doi: 10.1128/JVI.00196-18. Print 2018 Jun 1. PubMed |
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.
Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV.
Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009. Epub 2018 May 31.
PubMed
Associated Plasmids |
Probing labeling-induced lysosome alterations in living cells by imaging-derived mean squared displacement analysis. Durso W, D'Autilia F, Amodeo R, Marchetti L, Cardarelli F. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2704-2709. doi: 10.1016/j.bbrc.2018.08.028. Epub 2018 Aug 9. PubMed |
Spherical Nucleic Acid Architecture Can Improve the Efficacy of Polycation-Mediated siRNA Delivery. Melamed JR, Kreuzberger NL, Goyal R, Day ES. Mol Ther Nucleic Acids. 2018 Sep 7;12:207-219. doi: 10.1016/j.omtn.2018.05.008. Epub 2018 Jun 2. PubMed |
Polyethylenimine-Spherical Nucleic Acid Nanoparticles against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells. Melamed JR, Ioele SA, Hannum AJ, Ullman VM, Day ES. Mol Pharm. 2018 Nov 5;15(11):5135-5145. doi: 10.1021/acs.molpharmaceut.8b00707. Epub 2018 Oct 11. PubMed |
A platform for assessing outer segment fate in primary human fetal RPE cultures. Zhang Q, Presswalla F, Feathers K, Cao X, Hughes BA, Zacks DN, Thompson DA, Miller JML. Exp Eye Res. 2019 Jan;178:212-222. doi: 10.1016/j.exer.2018.10.008. Epub 2018 Oct 15. PubMed |
Murine Leukemia Virus Glycosylated Gag Reduces Murine SERINC5 Protein Expression at Steady-State Levels via the Endosome/Lysosome Pathway to Counteract SERINC5 Antiretroviral Activity. Li S, Ahmad I, Shi J, Wang B, Yu C, Zhang L, Zheng YH. J Virol. 2019 Jan 4;93(2). pii: JVI.01651-18. doi: 10.1128/JVI.01651-18. Print 2019 Jan 15. PubMed |
Layer-by-layer assembled gold nanoshells for the intracellular delivery of miR-34a. Goyal R, Kapadia CH, Melamed JR, Riley RS, Day ES. Cell Mol Bioeng. 2018 Oct;11(5):383-396. doi: 10.1007/s12195-018-0535-x. Epub 2018 Jun 6. PubMed |
Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility. Yeshaw WM, van der Zwaag M, Pinto F, Lahaye LL, Faber AI, Gomez-Sanchez R, Dolga AM, Poland C, Monaco AP, van IJzendoorn SC, Grzeschik NA, Velayos-Baeza A, Sibon OC. Elife. 2019 Feb 11;8. pii: 43561. doi: 10.7554/eLife.43561. PubMed |
Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis. Fernandez-Mosquera L, Yambire KF, Couto R, Pereyra L, Pabis K, Ponsford AH, Diogo CV, Stagi M, Milosevic I, Raimundo N. Autophagy. 2019 Sep;15(9):1572-1591. doi: 10.1080/15548627.2019.1586256. Epub 2019 Mar 27. PubMed |
Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis. Drews K, Calgi MP, Harrison WC, Drews CM, Costa-Pinheiro P, Shaw JJP, Jobe KA, Nelson EA, Han JD, Fox T, White JM, Kester M. J Virol. 2019 May 29;93(12). pii: JVI.00017-19. doi: 10.1128/JVI.00017-19. Print 2019 Jun 15. PubMed |
A mouse model for SPG48 reveals a block of autophagic flux upon disruption of adaptor protein complex five. Khundadze M, Ribaudo F, Hussain A, Rosentreter J, Nietzsche S, Thelen M, Winter D, Hoffmann B, Afzal MA, Hermann T, de Heus C, Piskor EM, Kosan C, Franzka P, von Kleist L, Stauber T, Klumperman J, Damme M, Proikas-Cezanne T, Hubner CA. Neurobiol Dis. 2019 Jul;127:419-431. doi: 10.1016/j.nbd.2019.03.026. Epub 2019 Mar 28. PubMed |
A novel bungarotoxin binding site-tagged construct reveals MAPK-dependent Kv4.2 trafficking. Tabor GT, Park JM, Murphy JG, Hu JH, Hoffman DA. Mol Cell Neurosci. 2019 Jul;98:121-130. doi: 10.1016/j.mcn.2019.06.007. Epub 2019 Jun 15. PubMed |
Lysosomal Regulation of Inter-mitochondrial Contact Fate and Motility in Charcot-Marie-Tooth Type 2. Wong YC, Peng W, Krainc D. Dev Cell. 2019 Aug 5;50(3):339-354.e4. doi: 10.1016/j.devcel.2019.05.033. Epub 2019 Jun 20. PubMed |
The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover. Juanes MA, Isnardon D, Badache A, Brasselet S, Mavrakis M, Goode BL. J Cell Biol. 2019 Oct 7;218(10):3415-3435. doi: 10.1083/jcb.201904165. Epub 2019 Aug 30. PubMed |
Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5. Scheefhals N, Catsburg LAE, Westerveld ML, Blanpied TA, Hoogenraad CC, MacGillavry HD. Cell Rep. 2019 Oct 8;29(2):258-269.e8. doi: 10.1016/j.celrep.2019.08.102. PubMed |
Abeta modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism. Lee HN, Sim KM, Kim H, Ju J, Pae AN, Park JB, Ryu H, Seong J. Sci Rep. 2019 Oct 29;9(1):15557. doi: 10.1038/s41598-019-51914-2. PubMed |
A reference library for assigning protein subcellular localizations by image-based machine learning.
Schormann W, Hariharan S, Andrews DW.
J Cell Biol. 2020 Mar 2;219(3). pii: 133635. doi: 10.1083/jcb.201904090.
PubMed
Associated Plasmids |
An optimized toolbox for the optogenetic control of intracellular transport.
Nijenhuis W, van Grinsven MMP, Kapitein LC.
J Cell Biol. 2020 Apr 6;219(4). pii: 133834. doi: 10.1083/jcb.201907149.
PubMed
Associated Plasmids |
The Lysosomotropic Activity of Hydrophobic Weak Base Drugs is Mediated via Their Intercalation into the Lysosomal Membrane. Stark M, Silva TFD, Levin G, Machuqueiro M, Assaraf YG. Cells. 2020 Apr 27;9(5). pii: cells9051082. doi: 10.3390/cells9051082. PubMed |
Saikosaponin D inhibits autophagosomelysosome fusion and induces autophagyindependent apoptosis in MDAMB231 breast cancer cells. Fu R, Zhang L, Li Y, Li B, Ming Y, Li Z, Xing H, Chen J. Mol Med Rep. 2020 Aug;22(2):1026-1034. doi: 10.3892/mmr.2020.11155. Epub 2020 May 18. PubMed |
Super-resolution observation of lysosomal dynamics with fluorescent gold nanoparticles. Qiu K, Du Y, Liu J, Guan JL, Chao H, Diao J. Theranostics. 2020 May 15;10(13):6072-6081. doi: 10.7150/thno.42134. eCollection 2020. PubMed |
Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability. Almacellas E, Pelletier J, Day C, Ambrosio S, Tauler A, Mauvezin C. Autophagy. 2021 Mar;17(3):796-813. doi: 10.1080/15548627.2020.1764727. Epub 2020 Jun 23. PubMed |
Thrombin-activated PAR1 membrane expression is regulated by Rab11a-RCP complex dissociation. Alvarez-Arce A, Lee-Rivera I, Lopez E, Lopez-Colome AM. Cell Signal. 2020 Nov;75:109748. doi: 10.1016/j.cellsig.2020.109748. Epub 2020 Aug 27. PubMed |
Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains. Vaillant-Beuchot L, Mary A, Pardossi-Piquard R, Bourgeois A, Lauritzen I, Eysert F, Kinoshita PF, Cazareth J, Badot C, Fragaki K, Bussiere R, Martin C, Mary R, Bauer C, Pagnotta S, Paquis-Flucklinger V, Buee-Scherrer V, Buee L, Lacas-Gervais S, Checler F, Chami M. Acta Neuropathol. 2021 Jan;141(1):39-65. doi: 10.1007/s00401-020-02234-7. Epub 2020 Oct 20. PubMed |
Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses. Houston R, Sekine S, Calderon MJ, Seifuddin F, Wang G, Kawagishi H, Malide DA, Li Y, Gucek M, Pirooznia M, Nelson AJ, Stokes MP, Stewart-Ornstein J, Mullett SJ, Wendell SG, Watkins SC, Finkel T, Sekine Y. PLoS Biol. 2020 Nov 30;18(11):e3000981. doi: 10.1371/journal.pbio.3000981. eCollection 2020 Nov. PubMed |
Inhibition of Wnt signaling by Frizzled7 antibody-coated nanoshells sensitizes triple-negative breast cancer cells to the autophagy regulator chloroquine. Wang J, Dang MN, Day ES. Nano Res. 2020 Jun;13(6):1693-1703. doi: 10.1007/s12274-020-2795-8. Epub 2020 Apr 25. PubMed |
The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes. Lu M, van Tartwijk FW, Lin JQ, Nijenhuis W, Parutto P, Fantham M, Christensen CN, Avezov E, Holt CE, Tunnacliffe A, Holcman D, Kapitein L, Schierle GSK, Kaminski CF. Sci Adv. 2020 Dec 16;6(51). pii: 6/51/eabc7209. doi: 10.1126/sciadv.abc7209. Print 2020 Dec. PubMed |
Mitochondria-lysosome membrane contacts are defective in GDAP1-related Charcot-Marie-Tooth disease. Cantarero L, Juarez-Escoto E, Civera-Tregon A, Rodriguez-Sanz M, Roldan M, Benitez R, Hoenicka J, Palau F. Hum Mol Genet. 2021 Jan 21;29(22):3589-3605. doi: 10.1093/hmg/ddaa243. PubMed |
In situ measurements of intracellular thermal conductivity using heater-thermometer hybrid diamond nanosensors. Sotoma S, Zhong C, Kah JCY, Yamashita H, Plakhotnik T, Harada Y, Suzuki M. Sci Adv. 2021 Jan 15;7(3). pii: 7/3/eabd7888. doi: 10.1126/sciadv.abd7888. Print 2021 Jan. PubMed |
Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation. Khundadze M, Ribaudo F, Hussain A, Stahlberg H, Brocke-Ahmadinejad N, Franzka P, Varga RE, Zarkovic M, Pungsrinont T, Kokal M, Ganley IG, Beetz C, Sylvester M, Hubner CA. Autophagy. 2021 Mar 9:1-17. doi: 10.1080/15548627.2021.1891848. PubMed |
Optogenetic Tools for Manipulating Protein Subcellular Localization and Intracellular Signaling at Organelle Contact Sites. Benedetti L. Curr Protoc. 2021 Mar;1(3):e71. doi: 10.1002/cpz1.71. PubMed |
Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson's disease. Kim S, Wong YC, Gao F, Krainc D. Nat Commun. 2021 Mar 22;12(1):1807. doi: 10.1038/s41467-021-22113-3. PubMed |
TDP-43 and PINK1 mediate CHCHD10(S59L) mutation-induced defects in Drosophila and in vitro. Baek M, Choe YJ, Bannwarth S, Kim J, Maitra S, Dorn GW 2nd, Taylor JP, Paquis-Flucklinger V, Kim NC. Nat Commun. 2021 Mar 26;12(1):1924. doi: 10.1038/s41467-021-22145-9. PubMed |
Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH.
Chin MY, Patwardhan AR, Ang KH, Wang AL, Alquezar C, Welch M, Nguyen PT, Grabe M, Molofsky AV, Arkin MR, Kao AW.
ACS Sens. 2021 Jun 8. doi: 10.1021/acssensors.0c02318.
PubMed
Associated Plasmids |
CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice. Gan L, Liu D, Liu J, Chen E, Chen C, Liu L, Hu H, Guan X, Ma W, Zhang Y, He Y, Liu B, Tang S, Jiang W, Xue J, Xin H. Signal Transduct Target Ther. 2021 Jun 11;6(1):223. doi: 10.1038/s41392-021-00625-0. PubMed |
Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD. George G, Ninagawa S, Yagi H, Furukawa JI, Hashii N, Ishii-Watabe A, Deng Y, Matsushita K, Ishikawa T, Mamahit YP, Maki Y, Kajihara Y, Kato K, Okada T, Mori K. Elife. 2021 Oct 26;10. pii: 70357. doi: 10.7554/eLife.70357. PubMed |
Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A. Creighton BA, Afriyie S, Ajit D, Casingal CR, Voos KM, Reger J, Burch AM, Dyne E, Bay J, Huang JK, Anton ES, Fu MM, Lorenzo DN. Elife. 2021 Nov 23;10. pii: 69815. doi: 10.7554/eLife.69815. PubMed |
A novel live-cell imaging assay reveals regulation of endosome maturation. Podinovskaia M, Prescianotto-Baschong C, Buser DP, Spang A. Elife. 2021 Nov 30;10. pii: 70982. doi: 10.7554/eLife.70982. PubMed |
Engineered HaloTag variants for fluorescence lifetime multiplexing.
Frei MS, Tarnawski M, Roberti MJ, Koch B, Hiblot J, Johnsson K.
Nat Methods. 2021 Dec 16. pii: 10.1038/s41592-021-01341-x. doi: 10.1038/s41592-021-01341-x.
PubMed
Associated Plasmids |
Fluorescence Lifetime Imaging of pH along the Secretory Pathway.
Linders PTA, Ioannidis M, Ter Beest M, van den Bogaart G.
ACS Chem Biol. 2022 Jan 21;17(1):240-251. doi: 10.1021/acschembio.1c00907. Epub 2022 Jan 10.
PubMed
Associated Plasmids |
USP17 is required for peripheral trafficking of lysosomes. Lin J, McCann AP, Sereesongsaeng N, Burden JM, Alsa'd AA, Burden RE, Micu I, Williams R, Van Schaeybroeck S, Evergren E, Mullan P, Simpson JC, Scott CJ, Burrows JF. EMBO Rep. 2022 Apr 5;23(4):e51932. doi: 10.15252/embr.202051932. Epub 2022 Jan 26. PubMed |
ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice. Kouzu H, Tatekoshi Y, Chang HC, Shapiro JS, McGee WA, De Jesus A, Ben-Sahra I, Arany Z, Leor J, Chen C, Blackshear PJ, Ardehali H. J Clin Invest. 2022 May 16;132(10). pii: 154491. doi: 10.1172/JCI154491. PubMed |
Live cell microscopy of mitochondria-lysosome contact site formation and tethering dynamics. Belton TB, Leisten ED, Cisneros J, Wong YC. STAR Protoc. 2022 Mar 18;3(2):101262. doi: 10.1016/j.xpro.2022.101262. eCollection 2022 Jun 17. PubMed |
Overexpression of progranulin increases pathological protein accumulation by suppressing autophagic flux. Tanaka Y, Kusumoto SY, Honma Y, Takeya K, Eto M. Biochem Biophys Res Commun. 2022 Jun 30;611:78-84. doi: 10.1016/j.bbrc.2022.04.064. Epub 2022 Apr 16. PubMed |
Abemaciclib and Vacuolin-1 induce vacuole-like autolysosome formation - A new tool to study autophagosome-lysosome fusion. Tanaka Y, Hino H, Takeya K, Eto M. Biochem Biophys Res Commun. 2022 Jul 23;614:191-197. doi: 10.1016/j.bbrc.2022.05.027. Epub 2022 May 14. PubMed |
Therapeutic advantage of targeting lysosomal membrane integrity supported by lysophagy in malignant glioma. Jing Y, Kobayashi M, Vu HT, Kasahara A, Chen X, Pham LT, Kurayoshi K, Tadokoro Y, Ueno M, Todo T, Nakada M, Hirao A. Cancer Sci. 2022 Aug;113(8):2716-2726. doi: 10.1111/cas.15451. Epub 2022 Jun 27. PubMed |
Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation.
Kuey C, Sittewelle M, Larocque G, Hernandez-Gonzalez M, Royle SJ.
Elife. 2022 Jul 19;11. pii: 78929. doi: 10.7554/eLife.78929.
PubMed
Associated Plasmids |
A phosphoinositide signalling pathway mediates rapid lysosomal repair. Tan JX, Finkel T. Nature. 2022 Sep;609(7928):815-821. doi: 10.1038/s41586-022-05164-4. Epub 2022 Sep 7. PubMed |
Restoration of Cathepsin D Level via L-Serine Attenuates PPA-Induced Lysosomal Dysfunction in Neuronal Cells. Jeon H, Kim YJ, Hwang SK, Seo J, Mun JY. Int J Mol Sci. 2022 Sep 13;23(18):10613. doi: 10.3390/ijms231810613. PubMed |
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA. Sen A, Kallabis S, Gaedke F, Jungst C, Boix J, Nuchel J, Maliphol K, Hofmann J, Schauss AC, Kruger M, Wiesner RJ, Pla-Martin D. Nat Commun. 2022 Nov 7;13(1):6704. doi: 10.1038/s41467-022-34205-9. PubMed |
Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage. Raj N, Greune L, Kahms M, Mildner K, Franzkoch R, Psathaki OE, Zobel T, Zeuschner D, Klingauf J, Gerke V. Adv Sci (Weinh). 2023 May;10(13):e2300244. doi: 10.1002/advs.202300244. Epub 2023 Mar 20. PubMed |
Tamoxifen Affects Aquaporin-3 Expression and Subcellular Localization in Rat and Human Renal Collecting Ducts. Tingskov SJ, D'Agostino M, Login FH, Tamma G, Nejsum LN, Norregaard R. Cells. 2023 Apr 12;12(8):1140. doi: 10.3390/cells12081140. PubMed |
Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence. Soha SA, Santhireswaran A, Huq S, Casimir-Powell J, Jenkins N, Hodgson GK, Sugiyama M, Antonescu CN, Impellizzeri S, Botelho RJ. Mol Biol Cell. 2023 Sep 1;34(10):ar96. doi: 10.1091/mbc.E22-06-0200. Epub 2023 Jul 5. PubMed |
Parkin regulates amino acid homeostasis at mitochondria-lysosome (M/L) contact sites in Parkinson's disease. Peng W, Schroder LF, Song P, Wong YC, Krainc D. Sci Adv. 2023 Jul 21;9(29):eadh3347. doi: 10.1126/sciadv.adh3347. Epub 2023 Jul 19. PubMed |
Pre-T cell receptor localization and trafficking are independent of its signaling. Smid AI, Garforth SJ, Obaid MS, Bollons HR, James JR. J Cell Biol. 2023 Oct 2;222(10):e202212106. doi: 10.1083/jcb.202212106. Epub 2023 Jul 26. PubMed |
Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages. Pellegrino E, Aylan B, Bussi C, Fearns A, Bernard EM, Athanasiadi N, Santucci P, Botella L, Gutierrez MG. J Cell Biol. 2023 Dec 4;222(12):e202303066. doi: 10.1083/jcb.202303066. Epub 2023 Sep 22. PubMed |
Lysosomal proteomics reveals mechanisms of neuronal apoE4associated lysosomal dysfunction. Krogsaeter EK, McKetney J, Marquez A, Cakir Z, Stevenson E, Jang GM, Rao A, Zhou A, Huang Y, Krogan NJ, Swaney DL. bioRxiv [Preprint]. 2023 Oct 2:2023.10.02.560519. doi: 10.1101/2023.10.02.560519. PubMed |
Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux. Tanaka Y, Kozuma L, Hino H, Takeya K, Eto M. Biochem Biophys Rep. 2024 Apr 1;38:101705. doi: 10.1016/j.bbrep.2024.101705. eCollection 2024 Jul. PubMed |
Impaired mitochondrial morphological plasticity and failure of mitophagy associated with the G11778A mutation of LHON. Pasqualotto BA, Nelson A, Deheshi S, Sheldon CA, Vogl AW, Rintoul GL. Biochem Biophys Res Commun. 2024 Aug 20;721:150119. doi: 10.1016/j.bbrc.2024.150119. Epub 2024 May 14. PubMed |
Mitochondrial alterations in fibroblasts from sporadic Alzheimer's disease (AD) patients correlate with AD-related clinical hallmarks. Eysert F, Kinoshita PF, Lagarde J, Lacas-Gervais S, Xicota L, Dorothee G, Bottlaender M, Checler F, Potier MC, Sarazin M, Chami M. Acta Neuropathol Commun. 2024 Jun 8;12(1):90. doi: 10.1186/s40478-024-01807-x. PubMed |
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